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Journals / Türkiye Parazitoloji Dergisi / 2002 / Cilt: 26 - Sayı: 3

Ascaris lumbricoides ile enfekte kişilerde bazı sitokilerin seviyesi

The level of some cytokines in persons infected with Ascaris lumbricoides

Mohammed Rafiq TAWFIQ
Mehmet S. TEKEREKOĞLU
Nihayet MEHMET
Barış OTLU
Rıza DURMAZ
Pages
271–273
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The elevated ratios of TNF-$alpha$, IL-2, IL-2R and IL-6 levels were significantly different (p

📌 3 Key Takeaways

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Objective & Hypothesis:The levels of some cytokines were determined in 64 sera collected from 34 persons (13 male and 21 female) infected with Ascaris lumbricoides and 30 healthy controls (12 male, 18 female).
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Key Findings & Data:Serum levels of TNF-$alpha$, IL-lß$beta$, IL-2R, IL6, and IL8 were determined by a solid-phase two site chemiluminescent enzyme immunometric assay, while IL-2, IL-4, and IL-10 levels were measured by the enzyme-linked immunosorbent assay (ELISA).
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Conclusion & Impact:The elevated ratios of TNF-$alpha$, IL-2, IL-2R and IL-6 levels were significantly different (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The levels of some cytokines were determined in 64 sera collected from 34 persons (13 male and 21 female) infected with Ascaris lumbricoides and 30 healthy controls (12 male, 18 female). Serum levels of TNF-$alpha$, IL-lß$beta$, IL-2R, IL6, and IL8 were determined by a solid-phase two site chemiluminescent enzyme immunometric assay, while IL-2, IL-4, and IL-10 levels were measured by the enzyme-linked immunosorbent assay (ELISA). The cytokine, which was increased the most, was IL-2R with an elevated level in 88.23% of the subjects infected with Ascaris lumbricoides. This was followed by IL-2 and TNF-$alpha$ (85.29%), IL-6 (32.35%), IL-8 (20.58%), IL-l$beta$ and IL-4 (14.71%), and IL-10 (5.88%). The elevated ratios of TNF-$alpha$, IL-2, IL-2R and IL-6 levels were significantly different (p

Özet

Ascaris lumbricoides ile enfekte 34 (13 erkek ve 21 kadın) ve 30 sağlılıkla kontrol grubundan (12 erkek ve 18 kadın) alınan toplam 64 serum örneği bazı sitokinlerinin seviyelerini tespit etmek için test edildi. TNF-$alpha$, IL-l$beta$, IL-2R, IL6 ve IL8 'in serum seviyeleri solid faz kemilüminisans enzim immunometrik assay ile tespit edilirken IL-2, IL-4 ve IL-10 seviyeleri Enzim Lynked immunosorbent Assay (ELISA) ile ölçüldü. En çok artan sitokin IL-2R idi, Ascaris lumbricoides ile enfekte olan kişilerin %88.23' ünde yükselmiştir. Bunu IL-2 ve TNF-$alpha$ (%85.29), IL-6 (%32.35), IL-8 (%20.58), IL-l$beta$ ve IL-4 (%14.71) ve IL-10 (%5.88) takip ettiği görülmüştür. TNF-$alpha$, IL-2, IL-2R ve IL-6 seviyelerindeki artış oranları belirgin olarak farklı olmuştur (p

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Cite This Article

TAWFIQ, M. R., TEKEREKOĞLU, M. S., MEHMET, N., OTLU, B., DURMAZ, R. (2022). Ascaris lumbricoides ile enfekte kişilerde bazı sitokilerin seviyesi. Türkiye Parazitoloji Dergisi, Cilt: 26 - Sayı: 3, 271–273. https://ajindex.com/articles/631014

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