Journals / Türkiye Parazitoloji Dergisi / 2007 / Cilt: 31 - Sayı: 2

Investigation of the germicidal effect of usnic acid, betadine, savlosol, and desderman on the protoscolexes of lung hydatid cysts

Akciğer hidatik kistlerinde usnik asit, betadine savlasol ve desderman'ın protoskoleksler üzerine germisid etkinliğinin araştırılması

Pages
101–104
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that usnic acid did not completely kill the scolexes in 15 minutes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Injecting scolicidal agents into the intact hydatid cyst and packing the operative field with sponges soaked in scolicidal agents have been used to avoid dissemination of the parasite into the pleural cavity and bronchial system during surgery.
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Key Findings & Data:For this reason, usnic acid, betadine® (%10 povidine iodine), savlosol® (15% cetrimide 1.5% chlorhexidine), and desderman® (96% ethanol and 2-biphenylol) and their various dilutions were used.
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Conclusion & Impact:It was found that usnic acid did not completely kill the scolexes in 15 minutes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Injecting scolicidal agents into the intact hydatid cyst and packing the operative field with sponges soaked in scolicidal agents have been used to avoid dissemination of the parasite into the pleural cavity and bronchial system during surgery. The aim of this study was to determine the scolicidal property of different concentrations and exposure times of various agents on the protoscolexes. For this reason, usnic acid, betadine® (%10 povidine iodine), savlosol® (15% cetrimide 1.5% chlorhexidine), and desderman® (96% ethanol and 2-biphenylol) and their various dilutions were used. Protoscolexes were obtained from lungs containing cysts of the naturally infected sheep and viability was determined by dye uptake (0.1% Eosin). It was found that usnic acid did not completely kill the scolexes in 15 minutes. Betadine®, savlosol®, and desderman® was strongly germicidal in 15 minutes. Savlosol® was found to have a germicidal effect at the lowest concentration among the agents studied

Özet

İntakt hidatik kistlerde kist içine germisid ajan injeksiyonu ve germisid ajan emdirilmiş tamponlar ile kist etrafının sarılması cerrahi sırasında parazitin plevral aralık ve bronşial sisteme yayılmasını engellemek için kullanılan bir yöntemdir. Bu çalışmada farklı konsantrasyon ve zamanlarda çeşitli ajanların protoskoleksler üzerine germisid etkilerini saptamayı amaçladık. Bu amaçla; Usnik asit, Betadine® (%10 povidine iodine), Savlosol® (%15 cetrimide - %1,5 chlorhexidine), Desderman® (%96 ethanol ve 2-biphenylol) ve dilüe formları kullanıldı. Protoskoleksler doğal infekte koyunların hidatik kistli akciğerlerinden elde edildi ve canlılık oranları %0.1 eosin ile saptandı. Usnik asit 15. dakikada yeterli germisid etkiye sahip değildi. Betadine®, Savlosol® ve Desderman® 15. dakikada güçlü germisid etkiye sahipti. Savlosol® bu ajanlar içinde en düşük konsantrasyonda germisid etkiye sahip olan ajandı.

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Cite This Article

ÇİFTÇİ, İ. H., DİLEK, O. N., SOLAK, O., ESME, H. (2022). Investigation of the germicidal effect of usnic acid, betadine, savlosol, and desderman on the protoscolexes of lung hydatid cysts. Türkiye Parazitoloji Dergisi, Cilt: 31 - Sayı: 2, 101–104. https://ajindex.com/articles/630736

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References (13)

  1. Altındiş M, Arıkan Y, Çetinkaya Z, Polat C, Yılmaz S, Akbulut G, Dilek ON, Gökçe O, 2004. Octenidine hydrochloride in hydatid disease. J Invest Surg, 17: 41-44
  2. Baraks A, Wakra N, Yamout F, 1980. Methemoglobinemia during surgical excision of hydatid cysts. Middle East J Anaesthesiol, 5: 509-513
  3. Besim H, Karayalçın K, Hamamcı O, Güngör C, Korkmaz A, 1998. Scolicidal agents in hydatid cyst surgery. HPB Surg, 10: 347-351
  4. Castellano G, Moreno-Sanchez D, Gutierrez J, Moreno- Gonzalez E, Colina F, Solis-Herruzo JA, 1994. Caustic sclerosing cholangitis. Report of four cases and a cumulative review of the literature. Hepatogastroenterology, 41: 458-470
  5. Doğan R,Yüksel M, Çetin G, Süzer K, Alp M, Kaya S, Unlu M, Moldibi B, 1989. Surgical treatment of hydatid cysts of the lung: report on 1055 patients. Thorax, 44: 192-199
  6. Filice C, Pirola F, Brunetti E, Dughetti S, Strosselli M, Foglieni CS, 1990. A new therapeutic approach for hydatid liver cysts. Aspiration and alcohol injection under sonographic guidance. Gastroenterology, 98: 1366-1368
  7. Fournet A, Ferreira ME, Rojas de Arias A, Torres de Ortiz S, Inchausti A, Yaluff G, Quilhot W, Fernandez E, Hidalgo ME, 1997. Activity of compounds isolated from Chilean lichens againts experimental cutaneous leishmaniasis. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol, 116: 51–54
  8. Giorgio A, Tarantino L, Francica G, Mariniello N, Aloisio T, Soscia E, Pierri G, 1992. Unilocular hydatid liver cysts: treatment with US guided, double percutaneous aspiration and alcohol injection. Radiology, 184: 705-710
  9. Ingolfsdottir K, Chung GA, Skulason VG, Gissurarson SR, Vilhelmsdottir M, 1998. Antimycobacterial activity of lichen metabolites in vitro. Eur J Pharm Sci, 6: 141–144
  10. Kayaalp C, Balkan M, Aydin C, Ozgurtas T, Tanyuksel M, Kirimlioglu V, Akoglu M, Oner K, Pekcan M, 2001. Hypertonic saline in hydatid disease. World J Surg, 25: 975-979
  11. Kilani T, El Hammami S, 2002. Pulmonary hydatid and other lung parasitic infections. Curr Opin Pulm Med, 8: 218-223
  12. Landa Garcia JI, Alonso E, Gonzales-Uriarte J, Rodriguez Romano A, 1997. Evaluation of scolicidal agents in an experimental hydatid disease model. Eur Surg Res, 29: 202–208
  13. Montaggian H, Saidi F, 1978. Postoperative recurrence of hydatid disease. Br J Surg, 165: 237-242 14. Odabaşoğlu F, Çakır A, Süleyman H, Aslan A, Bayır Y, Halıcı M, Kazaz C, 2006. Gastroprotective and antioxidant effects of usnic acid on indomethacin induced gastric