Journals / Türkiye Parazitoloji Dergisi / 2009 / Cilt: 33 - Sayı: 4

Case report: Two Imported plasmodium falciparum cases

Olgu sunumu: Yurtdışı kaynaklı iki plasmodium falciparum olgusu

Pages
280–282
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, two cases with different clinical manifestations were presented to emphasize the importance of timing in starting the correct treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:A 23 year-old Pakistani man presented at the emergency clinic of Tepecik Research and Training Hospital with the symptoms such as fever (39.3º C), blurred consciousness, subicteric sclera and splenomegalia.
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Key Findings & Data:In the laboratory examination, a slightly increase of the liver enzymes and anemia were detected.
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Conclusion & Impact:In this study, two cases with different clinical manifestations were presented to emphasize the importance of timing in starting the correct treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 23 year-old Pakistani man presented at the emergency clinic of Tepecik Research and Training Hospital with the symptoms such as fever (39.3º C), blurred consciousness, subicteric sclera and splenomegalia. In the laboratory examination, a slightly increase of the liver enzymes and anemia were detected. The gametocytes and trophozoites of Plasmodium falciparum were seen in a bone marrow aspiration and treatment was started with quinine and doxycycline but since resistance was detected to these medicines, mefloquine was chosen as alternative therapy. He was cured and discharged. The second case was also a Pakistani 20-year old man and he was a friend of first case. He presented at our hospital with the symptoms such as fever (39.4º C), closed consciousness, icteric sclera and systolic soufflé in all cardiac foci. During the laboratory examination, severe anemia and trombocytopenia, and an increase in the liver enzymes were found. P. falciparum gametocytes and young trophozoites were seen in a blood smear stained with Giemsa. For treatment, mefloquine was used but unfortunately the patient died due to an adult respiratory distress syndrome (ARDS) complication. In this study, two cases with different clinical manifestations were presented to emphasize the importance of timing in starting the correct treatment.

Özet

23 yaşında Pakistanlı erkek olgu ateş yüksekliği, bilinç bulanıklığı ile Tepecik Eğitim ve Araştırma Hastanesi acil servisine başvurusunda 39.3 ºC ateş, bilinç bulanıklığı, subikterik skleralar ve splenomegali bulguları saptanmıştır. Laboratuar tetkiklerinde karaciğer testlerinde hafif yükseklik ve anemi olduğu görülmüştür. Yapılan kemik iliği aspirasyonunda P. falciparum gametosit ve trofozoitleri görülerek falciparum sıtması tanısı konulmuş, kinin ve doksisiklin tedavisine başlanmış ancak dirençli bulunarak meflokin ile devam edilmiştir. Yine Pakistan'lı ve 20 yaşındaki ikinci olguda ise acil servise başvurusunda 39.4 ºC ateş, kapalı bilinç, ikterik skleralar ve tüm kardiyak odaklarda 2/6 sistolik üfürüm saptanmıştır. Laboratuar tetkiklerinde derin anemi ve trombositopeni, karaciğer testlerinde yükseklik saptanan olgunun kalın damla preparatında P. falciparum gametositleri görülmesi ile tanı konulmuştur. Her iki olguya uygun tedavi başlanmasına rağmen birinci olgu iyileşerek taburcu olurken ikinci olgu ARDS komplikasyonu nedeniyle kaybedildi. Bu çalışmada P. falciparum sıtması nedeniyle gelişen iki farklı klinik tablo sunulmuştur. Zamanında başlanan tedavi ile yanıt yüz güldürücü olurken, tersi durumda morbidite ve mortalitenin arttığının hatırlatılması amaçlanmıştır.

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Cite This Article

KIRAKLI, C., ÇEVİKEL, N., KUZUCU, L., TÖZ, Ö. S., KÖSE, Ş., AKKOÇLU, G. (2022). Case report: Two Imported plasmodium falciparum cases. Türkiye Parazitoloji Dergisi, Cilt: 33 - Sayı: 4, 280–282. https://ajindex.com/articles/630586

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