Investigating demodex folliculorum in patients with urological cancer

Objective & Hypothesis:Objective: In this study, it was aimed to determine frequency of Demodex folliculorum infestation in patients with urological cancers.

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Key Findings & Data:Methods: This study evaluated 49 patients with urological cancers; 31 sex-matched healthy individuals as a control group were included in the study between March 2011 and April 2012 at the Hospital of Mustafa Kemal University, School of Medicine, Urology Clinic.

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Conclusion & Impact:It was found that D. folliculorum frequency was significantly higher in the cancer group compared to the control group.

🔬Design:Research Article

📍Scope:2011 Verileri

⚙️Variables:Domain Parameters

Abstract

Objective: In this study, it was aimed to determine frequency of Demodex folliculorum infestation in patients with urological cancers. Methods: This study evaluated 49 patients with urological cancers; 31 sex-matched healthy individuals as a control group were included in the study between March 2011 and April 2012 at the Hospital of Mustafa Kemal University, School of Medicine, Urology Clinic. The demographic characteristics of the patients were recorded. Samples from the perineal region of the subjects were taken by standard method of superficial skin biopsy and evaluated by microscopy. Presence of five or more Demodex sp. in a cm2 was considered as positive.Results: Mean age was found to be 60.2±18.6 years. D. folliculorum was found to be positive in 11 (22.4%) of the patients with cancer and in 1 (3.2%) of the subjects in the control group. It was found that D. folliculorum frequency was significantly higher in the cancer group compared to the control group. No significant difference was found among the cancer groups in terms of D. folliculorum detection. In the cancer group, mean age was significantly higher in D. folliculorum positive patients than negative ones.Conclusion: It should be kept in mind that D. folliculorum incidence may increase in immunosuppressive states, such as cancer.

Özet

Amaç: Bu çalışmada, ürolojik kanserli hastalarda Demodex folliculorum sıklığının belirlenmesi amaçlandı. Yöntemler: Çalışmaya Mustafa Kemal Üniversitesi Tıp Fakültesi Hastanesi Üroloji Kliniği’ne Mart 2011-Nisan 2012 tarihleri arasında başvuran 49 ürolojik kanserli hasta ve kontrol grubu olarak yaş ve cinsiyeti uyumlu 31 sağlıklı birey dahil edildi. Hastaların demografik özellikleri kaydedildi. Bireylerin perine bölgesinden standart yüzeyel deri biyopsisi yöntemiyle örnek alındı ve mikroskobik olarak incelendi. Her bir cm2’de 5 ve daha fazla D. folliculorum görülmesi pozitif olarak değerlendirildi. Bulgular: Çalışmaya dahil edilen hastaların yaş ortalaması 60.2±18.6 olarak belirlendi. Kanser hastalarının 11’inde (%22.4), kontrol grubunun ise 1’inde (%3.2) D. folliculorum pozitif olarak değerlendirildi. Kanser tanısı olan grupta D. folliculorum sıklığının kontrol grubuna kıyasla anlamlı oranda yüksek olduğu saptandı. Kanser grupları arasında D. folliculorum saptanma yönünden istatistiksel olarak anlamlı bir farklılık bulunmadı. Kanserli grupta D. folliculorum pozitif olan hastaların yaş ortalamasının negatif olanlardan anlamlı oranda yüksek olduğu belirlendi. Sonuç: Kanser gibi immünsüpresyon durumlarında D. folliculorum görülme oranının artabileceği hatırda tutulmalıdır. (Turkiye Pa

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Cite This Article

YENGİL, E., GÖKÇE, H., İNCİ, M., RİFAİOĞLU, M. M., DEMİRTAŞ, O., İNCİ, M., YULA, E., KAYA, Ö. A. (2022). Investigating demodex folliculorum in patients with urological cancer. Türkiye Parazitoloji Dergisi, Cilt: 36 - Sayı: 4, 208–210. https://ajindex.com/articles/630406

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