Journals / Türkiye Parazitoloji Dergisi / 2014 / Cilt: 38 - Sayı: 3

Uludağ Üniversitesi Hastanesi ELISA Laboratuvarına 2002-2008 Yılları Arasında Toxoplasmosis Şüphesi ile Başvuran Hastaların Serolojik Sonuçlarının Değerlendirilmesi

Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008

Pages
141–146
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Results showed that the prevalence of anti-T. gondii IgG and IgM among women (29.2% and 2.02%, respectively) was higher than that of men (21.2% and 1.7%, respectively).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of this study is to investigate the distribution of anti-Toxoplasma gondii IgG and IgM antibodies in patients with suspected toxoplasmosis referred to the Uludağ University Medical School, Department of Medical Microbiology Enzyme-Linked Immunosorbent Assay (ELISA) laboratory over a 72-month period (March 2002-December 2008).
📊
Key Findings & Data:Results: Results showed that the prevalence of anti-T. gondii IgG and IgM among women (29.2% and 2.02%, respectively) was higher than that of men (21.2% and 1.7%, respectively).
💡
Conclusion & Impact:Conclusion: Although the study data may not reflect our entire province, it virtually turns out that the risk of toxoplasmosis must be seriously taken into account, particularly when approaching some risk groups, such as seronegative women of fertile age, pregnant women, and immunocompromised patients
🔬Design:Research Article
📍Scope:2002 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study is to investigate the distribution of anti-Toxoplasma gondii IgG and IgM antibodies in patients with suspected toxoplasmosis referred to the Uludağ University Medical School, Department of Medical Microbiology Enzyme-Linked Immunosorbent Assay (ELISA) laboratory over a 72-month period (March 2002-December 2008). Methods: The samples were analyzed using VIDAS (BioMérieux, France) IgG-avidity tests and the fluorescent enzyme-linked assay (ELFA) technique. Results: Results showed that the prevalence of anti-T. gondii IgG and IgM among women (29.2% and 2.02%, respectively) was higher than that of men (21.2% and 1.7%, respectively). The seroprevalence of anti-T. gondii IgG was 30.7% in childbearing-aged women, with rates ranging from 35.8% and 27.4% over the years. Avidity was found to be high, borderline, and lower (81.9%, 10.2%, and 7.9%, respectively) in the fertile age group of 166 women receiving the IgG avidity test. Conclusion: Although the study data may not reflect our entire province, it virtually turns out that the risk of toxoplasmosis must be seriously taken into account, particularly when approaching some risk groups, such as seronegative women of fertile age, pregnant women, and immunocompromised patients

Özet

Amaç: Bu çalışma, Uludağ Üniversitesi Tıp Fakültesi Tıbbi Mikrobiyoloji Anabilim Dalı ELISA laboratuvarına 72 aylık (Mart 2002 - Aralık 2008 tarihleri arasında) dönemde başvuran toksoplasmoz şüpheli hastalarda anti- Toxoplasma gondii IgG ve IgM antikorlarının dağılımını belirlemek amacıyla yapılmıştır. Yöntemler: Örnekler VIDAS (BioMérieux, France) IgG-avidite testi ve Fluorescent Enzyme-Linked Assay (ELFA) tekniği ile çalışılmıştır. Bulgular: Kadınlarda anti-T. gondii IgG ve IgM prevalansının (sırasıyla %29,2 ve %2,02) erkeklerdekinden (sırasıyla %21,2 ve %1,7) daha yüksek olduğu belirlenmiştir. Doğurgan dönemdeki kadınlarda anti-T. gondii IgG seroprevalansının %30,7 olduğu ve oranların %35,8 ile %27,4 arasında değiştiği izlenmiştir. IgG avidite testi çalışılmış doğurgan dönemdeki 166 kadının %81,9'unda yüksek, %10,2'sinde şüpheli sınırlar içinde, %7,9'unda düşük avidite değerlerine sahip olduğu saptanmıştır.Sonuç: Çalışma verileri ilimizin tamamını yansıtmamasına rağmen özellikle doğurgan dönemdeki seronegatif kadınlar, gebe kadınlar ve immünkompromize hastalar gibi risk gruplarında toksoplazmozun gözardı edilmemesi gerektiği düşünülmüştür

🔖

Cite This Article

ERCAN, İ., ALVER, O., GÖRAL, G. (2022). Uludağ Üniversitesi Hastanesi ELISA Laboratuvarına 2002-2008 Yılları Arasında Toxoplasmosis Şüphesi ile Başvuran Hastaların Serolojik Sonuçlarının Değerlendirilmesi. Türkiye Parazitoloji Dergisi, Cilt: 38 - Sayı: 3, 141–146. https://ajindex.com/articles/630254

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Joiner KA, Dubremetz JF. Toxoplasma gondii: a protozoan for the nineties. Infect Immun 1993; 61: 1169-72
  2. Montoya JG, Boothroyd JC, Kovacs JA. Toxoplasma gondii. Mandell GL, Bennett JE, Dolin R, edıtors. Mandell, Douglas, and Bennett’s Principles and Preactice of Infectious Diseases. Churchill Philidelphia: Livingstone Elsevier; 2010. p. 3495-526
  3. Alkan MZ, Tamer GS. Toxoplasma gondii. Topçu AW, Söyletir G, Doğanay M, edıtors. Enfeksiyon Hastalıkları ve Mikrobiyolojisi. İstanbul: Nobel Tıp Kitapevleri; 2008. p. 2534-51
  4. Montoya JG, Liesenfeld O. Toxoplasmosis. Lancet 2004; 363: 1965-76. [CrossRef] 5. Belsey MA. The epidemiology of infertility: a review with particular reference to sub-Saharan Africa. Bull World Health Organ 1976; 54: 319-41
  5. Tenter AM, Heckeroth AR, Weiss LM. Toxoplasma gondii: from animals to humans. Int J Parasitol 2000; 30: 1217-58. [CrossRef] 7. Swisher CN, Boyer K, McLeod R. Congenital toxoplasmosis. The Toxoplasmosis Study Group 1994; 1: 4-25
  6. Sabin AB, Feldman HA. Dyes as Microchemical Indicators of a New Immunity Phenomenon Affecting a Protozoon Parasite (Toxoplasma). Science 1948; 108: 660-3. [CrossRef] 9. Barker KF, Holliman RE. Laboratory techniques in the investigation of toxoplasmosis. Genitourin Med 1992; 68: 55-9
  7. Garcia JL, Navarro IT, Ogawa L, de Oliveira RC, Kobilka E. Seroprevalence, epidemiology and ocular evaluation of human toxoplasmosis in the rural zone Jauguapitã (Paraná) Brazil. Rev Panam Salud Publica 1999; 6: 157-63. [CrossRef] 11. Diza E, Frantzidou F, Souliou E, Arvanitidou M, Gioula G, Antoniadis A. Seroprevalence of Toxoplasma gondii in northern Greece during the last 20 years. Clin Microbiol Infect 2005; 11: 719-23. [CrossRef] 12. Babür C, Kılıç S, Taylan ÖA, Esen B. Evaluation of the Results of SabinFeldman Dye Tests at the Refik Saydam National Hygiene Center between 1995 and 2000. Turkiye Parazitol Derg 2002; 26: 124-8
  8. Tanyüksel M, Gun H, Erdal N, Haznedaroğlu T, Babur C, Baysallar M, et al. Comparison of Serological Tests In Diagnosis of Toxoplasmosis. Turkiye Parazitol Derg 1994; 18: 266-76
  9. Kılıçturgay K, Göral G, Gökırmak F, Töre O, Daregenli Ö, Gelişken Ö, et al. Distribution of Anti-toxoplasma antibodies in the general population of Bursa. Turkiye Parazitol Derg 1989; 13: 23-32
  10. Yiğit N, Aktaş AE, Uslu H, Aydın F, Babacan M. Investigation of AntiToxoplasma gondii Antibodies in the Sera of Patients Suspected of Having Toxoplasmosis Coming to the Department of Micro