Journals / Türkiye Parazitoloji Dergisi / 2015 / Cilt: 39 - Sayı: 3

An Autopsy Case of Sudden Death Caused by Cerebral Malaria Infection

Serebral Malarya Enfeksiyonuna Bağlı Ani Ölümle Sonuçlanan Otopsi Olgusu

Pages
234–237
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although domestic malaria cases has been decreasing in our country, it should be kept in mind that the malaria infection can be seen in persons travelling abroad to high endemic malarial regions and an appropriate antimalarial prophylaxis should be recommended to those overseas travellers

📌 3 Key Takeaways

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Objective & Hypothesis:Malaria is a lethal protozoan infection which is generally diagnosed antemortem and rarely diagnosed postmortem in a few cases.
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Key Findings & Data:A fifty five year old, Turkish citizen male has been referred for autopsy.
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Conclusion & Impact:Although domestic malaria cases has been decreasing in our country, it should be kept in mind that the malaria infection can be seen in persons travelling abroad to high endemic malarial regions and an appropriate antimalarial prophylaxis should be recommended to those overseas travellers
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Malaria is a lethal protozoan infection which is generally diagnosed antemortem and rarely diagnosed postmortem in a few cases. A fifty five year old, Turkish citizen male has been referred for autopsy. It has been found that he has gone abroad to work a month ago, however, quitted malaria prophylaxis before the intended end and brought into the emergecy department in an unconscious state.Following quinine and clindamycin treatment with the initial diagnosis of cerebral malaria, the case was reported to have died due to his general condition got worsened at the end of the third day of therapy.Histopathological evaluation of postmortem tissues was revealed haphazardly arranged minor bleedings and central vascular necrotic foci in the cerebrum, cerebelum and brain stem; light brown pigment containing cells around vasculature; and pigment containing cells in the spleen and bone marrow. Cerebral malaria has a rapid course and is rare but one of the lethal complications of infections with Plasmodium. Although domestic malaria cases has been decreasing in our country, it should be kept in mind that the malaria infection can be seen in persons travelling abroad to high endemic malarial regions and an appropriate antimalarial prophylaxis should be recommended to those overseas travellers

Özet

Sıtma genellikle antemortem, az sayıda vakada postmortem tanısı koyulabilen ölümcül bir protozoon enfeksiyonudur. Elli beş yaşında Türk vatandaşı olan erkek, Ekvator Ginesi'nden otopsi için gönderilmiştir. Bir ay önce yurt dışına çalışmak için gittiği ancak sıtma için proflaksisini yarım bıraktığı, orada bulunan bir hastanenin acil servisine bilinci kapalı halde götürüldüğü öğrenilmiştir. Serebral sıtma ön tanısıyla kinin ve klindamisin tedavisine başlanan vakanın 3. günün sonunda durumunun kötüleşmesi üzerine ex olduğu bildirilmiştir. Postmortem dokuların histopatolojik incelemesinde; beyin, beyincik ve beyin sapında; dağınık odaklar halinde küçük çaplı kanamalar, ortasında nekrotik vasküler yapılar, damar yapıları çevresinde açık kahverenkli pigment yüklü hücreler görüldüğü, dalak ve kemik iliğinde; pigment yüklü hücreler görüldüğü bildirilmiştir. Serebral malarya; Plasmodium enfeksiyonlarının nadir görülen hızlı seyirli ölümcül komplikasyonlarından biridir. Ülkemizde yerli sıtma olguları azalmasına rağmen, yurt dışına endemik bölgelere seyahat eden kişilerde sıtma enfeksiyonun görülebileceği unutulmamalı, bu bölgelere seyahat edeceklere uygun sıtma profilaksisi önerilmelidir

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Cite This Article

KOÇ, S., KARAYEL, F., YAĞMUR, G., ŞAHİN, M. F., GÜRLER, A. S., APAYDIN, N. (2022). An Autopsy Case of Sudden Death Caused by Cerebral Malaria Infection. Türkiye Parazitoloji Dergisi, Cilt: 39 - Sayı: 3, 234–237. https://ajindex.com/articles/630208

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