Journals / Türkiye Parazitoloji Dergisi / 2019 / Cilt: 43 - Sayı: 1

Lophomonas blattarum Associated Broncho- Pulmonary Infection After Immunotherapy: A Case Report and A Smart-phone Based Video of Trophozoite

İmmünoterapi Sonrasında Lophomonas blattarum ile İlişkili Bronkopulmoner Enfeksiyon: Bir Olgu Sunumu ve Trofozoitin Akıllı Telefon Kamerası ile Çekilmiş Videosu

Pages
44–46
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The morphologicalfeatures of L. blattarum were demonstrated by examining the bronchoalveolar lavage fluid of the patient under light microscopy.Additionally, URL (https://youtu.be/EQIAsFl6AJY) of a smart-phone based video of trophozoite of this patient was added intothis report.

📌 3 Key Takeaways

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Objective & Hypothesis:The frequency of bronchopulmonary protozoan infections has raised due to increased number of immunosuppressed patientsin recent years.
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Key Findings & Data:The drug regimens commonly used in bronchopulmonary infections are not effective against L. blattarum.Therefore, rapid and accurate diagnosis of L. blattarum infection is of great importance in the treatment success.
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Conclusion & Impact:The morphologicalfeatures of L. blattarum were demonstrated by examining the bronchoalveolar lavage fluid of the patient under light microscopy.Additionally, URL (https://youtu.be/EQIAsFl6AJY) of a smart-phone based video of trophozoite of this patient was added intothis report.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The frequency of bronchopulmonary protozoan infections has raised due to increased number of immunosuppressed patientsin recent years. One of them is Lophomonas blattarum which is a multi-flagellated protozoan parasite of termites and severalcockroach species. The drug regimens commonly used in bronchopulmonary infections are not effective against L. blattarum.Therefore, rapid and accurate diagnosis of L. blattarum infection is of great importance in the treatment success. The laboratorydiagnosis of L. blattarum infection is made on the basis of observation of the characteristic trophozoite in various samples. It isof a great importance to distinguish the protozoon from ciliated respiratory epithelium to avoid wrong positivity. The presentedcase developed an acute respiratory distress syndrome a short while after taking nivolumab immunotherapy. The morphologicalfeatures of L. blattarum were demonstrated by examining the bronchoalveolar lavage fluid of the patient under light microscopy.Additionally, URL (https://youtu.be/EQIAsFl6AJY) of a smart-phone based video of trophozoite of this patient was added intothis report.

Özet

Bronkopulmoner protozoon enfeksiyonlarının sıklığı son yıllarda immün yetmezlikli hastaların sayısındaki artışa bağlı olarak artmıştır. Bunlardan biri de termitlerin ve çeşitli hamam böceği türlerinin çoklu kamçılı protozoon paraziti olan Lophomonas blattarum’dur. Bronkopulmoner enfeksiyonlarda yaygın olarak kullanılan ilaç rejimleri L. blattarum’a karşı etkili değildir. Bu nedenle tedavi başarısında L. blattarum enfeksiyonunun hızlı ve doğru tanısı büyük öneme sahiptir. Lophomonas blattarum enfeksiyonunun laboratuvar tanısı karakteristik trofozoitin çeşitli örneklerde gözlenmesine dayanır. Yalancı pozitiflikten kaçınmak için protozoonun silli solunum epitelinden ayırt edilmesi büyük öneme sahiptir. Sunulan olgu nivolumab immünoterapisinden hemen sonra gelişen bir akut respiratuvar distress sendromu olgusudur. Hastanın bronkoalveolar lavaj sıvısı ışık mikroskobunda incelenerek L. blattarum’un morfolojik özellikleri ortaya konmuştur. Ek olarak, hastanın trofozoitinin akıllı telefon kamerası ile elde edilmiş video URL’si (https://youtu.be/EQIAsFl6AJY) olgu sunumuna eklenmiştir.

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Cite This Article

TURGAY, N., TÖZ, S., ZORBOZAN, O., UYSAL, A., BACAKOĞLU, F. (2022). Lophomonas blattarum Associated Broncho- Pulmonary Infection After Immunotherapy: A Case Report and A Smart-phone Based Video of Trophozoite. Türkiye Parazitoloji Dergisi, Cilt: 43 - Sayı: 1, 44–46. https://ajindex.com/articles/630042

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