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Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2004 / Cilt: 50 - Sayı: 4

The effects of acute phase reactants and lesion size on functional outcome in stroke patients

Akut faz reaktanları ve lezyon büyüklüğünün inmeli hastalarda fonksiyonel prognoza etkileri

Ertuğrul BOLAYIR
Aytekin AKYÜZ
Suat TOPAKTAŞ
Ayşenur TAŞ
Kerim YILMAZ
Ece KAPTANOĞLU
Pages
17–20
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was also a positive correlation between the C-reactive protein level and the lesion size (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Lesion size and acute phase reactants have been claimed to predict the prognosis in stroke, recently.
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Key Findings & Data:The aim of this study was to evaluate the relationship between the lesion size, acute phase reactants, and early functional outcome after ischemic stroke.In 64 patients with acute ischemic stroke, serum C-reactive protein, fibrinogen and ceruloplasmin levels were studied in the first 24 hours of the event.
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Conclusion & Impact:There was also a positive correlation between the C-reactive protein level and the lesion size (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Lesion size and acute phase reactants have been claimed to predict the prognosis in stroke, recently. However, there are contradictory results in the literature. The aim of this study was to evaluate the relationship between the lesion size, acute phase reactants, and early functional outcome after ischemic stroke.In 64 patients with acute ischemic stroke, serum C-reactive protein, fibrinogen and ceruloplasmin levels were studied in the first 24 hours of the event. All patients underwent brain scanning with tomography. Functional status of the patients were evaluated with Barthel Index in the first 24 hours and after 3 months. There was a positive correlation between the 3rd month and 1st day Barthel Index, whereas there was a negative correlation between the 3rd month Barthel Index and C-reactive protein, ceruloplasmin, lesion size and age. There was also a positive correlation between the C-reactive protein level and the lesion size (p

Özet

Son yıllarda, inmeli hastalarda prognozun akut faz reaktanları ve lezyon büyüklüğü ile ilişkili olabileceği öne sürülmüştür, ancak literatürde bu konuda birbirinden farklı sonuçlar vardır. Bu çalışmanın amacı inmeli hastalarda, erken dönemdeki fonksiyonel prognozun lezyon büyüklüğü ve akut faz reaktanları ile ilişkisini araştırmaktır. Akut iskemik inme tanısı konmuş olan 64 hastada ilk 24 saat içinde serum C-reaktif protein, fibrinojen, ve serüloplazmin düzeyleri ölçüldü. Tüm hastalara beyin tomografisi çekildi. Hastaların fonksiyonel durumları yatışlarının ilk 24 saati içinde ve olaydan 3 ay sonra Barthel İndeksi ile değerlendirildi. Üçüncü ay Barthel indeksi ile birinci gün Barthel indeksi arasında pozitif, üçüncü ay Barthel indeksi ile C-reaktif protein, serüloplazmin, lezyon büyüklüğü ve yaş arasında ise negatif korelasyon bulundu. Lezyon büyüklüğü ile C-reaktif protein arasında da pozitif korelasyon saptandı (p

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Cite This Article

BOLAYIR, E., AKYÜZ, A., TOPAKTAŞ, S., TAŞ, A., YILMAZ, K., KAPTANOĞLU, E. (2022). The effects of acute phase reactants and lesion size on functional outcome in stroke patients. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 50 - Sayı: 4, 17–20. https://ajindex.com/articles/629299

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