Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2011 / Cilt: 57 - Sayı: 2

Fibromyaljide otonom sinir sistemi disfonksiyonunun değerlendirilmesi

Evaluation of autonomic nervous system dysfunction in fibromyalgia

Pages
62–65
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It can be possible to determine the role of ANS in FM etiopathogenesis by studies evaluating the subsystems of ANS (cardiovascular reflex pathway, sympathetic cholinergic activity etc.) in which chronic symptoms of FM, especially anxiety and depression, are also considered.Turk J Phys Med Rehab 2011;57:62-5.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: There have been conflicting results of studies on autonomic nervous system (ANS) dysfunction in fibromyalgia (FM).
📊
Key Findings & Data:Materials and Methods: Twenty-seven female patients with FM and 18 healthy volunteer females as controls were included in the study.
💡
Conclusion & Impact:It can be possible to determine the role of ANS in FM etiopathogenesis by studies evaluating the subsystems of ANS (cardiovascular reflex pathway, sympathetic cholinergic activity etc.) in which chronic symptoms of FM, especially anxiety and depression, are also considered.Turk J Phys Med Rehab 2011;57:62-5.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: There have been conflicting results of studies on autonomic nervous system (ANS) dysfunction in fibromyalgia (FM). The aim of this study was to evaluate the sympathetic nervous system dysfunction via sympathetic skin response (SSR) recordings in patients with FM. Materials and Methods: Twenty-seven female patients with FM and 18 healthy volunteer females as controls were included in the study. All participant were administered the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI) and were questioned about chronic symptoms that are characteristic for FM. Right palmar SSRs were evoked by electrical stimulation of the median nerve at the wrist. Results: The FM patients had higher rates of most of the chronic symptoms of FM. There was no significant difference in SSR latency and amplitude between patients and controls (p>0.05). The patients with FM had no depression and anxiety according to the BDI and BAI mean scores. Conclusion: We did not find ANS dysfunction in the patients with FM. SSR may be an insufficient way of determining the whole ANS dysfunction as it only evaluates the sudomotor component. ANS dysfunction may be responsible for some of the chronic symptoms of FM and accompanying depression and anxiety (not observed in the present study) rather than taking part in the etiopathogenesis. It can be possible to determine the role of ANS in FM etiopathogenesis by studies evaluating the subsystems of ANS (cardiovascular reflex pathway, sympathetic cholinergic activity etc.) in which chronic symptoms of FM, especially anxiety and depression, are also considered.Turk J Phys Med Rehab 2011;57:62-5.

Özet

Amaç: Fibromyaljide (FM) otonom sinir sistemi (OSS) disfonksiyonu hakkındaki çalışmaların farklı sonuçları vardır. Bu çalışmadaki amacımız sempatik deri yanıtı (SDY) cevaplarını kullanarak FM hastalarında sempatik sinir sistemi disfonksiyonunu değerlendirmektir. Gereç ve Yöntem: Çalışmaya 27 fibromyaljili kadın hasta ve 18 sağlıklı gönüllü kadın kontrol alındı. FM hastaları ve sağlıklı kişiler Beck Depresyon Envanteri (BDE), Beck Anksiyete Envanteri (BAE) ve FM için karakteristik olan kronik semptomlar yönünden sorgulandı. Sağ el palmar SDY, median sinirin bilek hizasında elektriksel olarak uyarılması ile elde edildi. Bulgular: FM hastalarında kronik semptomların çoğu yüksek orandaydı. Hastaların ve kontrollerin SDY amplitüd ve latansları arasında istatistiksel olarak anlamlı bir fark yoktu (p>0,05). BDE ve BAE ortalama değerlerine göre FM hastalarında anksiyete ve depresyon yoktu. Sonuç: Bu çalışmada FM’de OSS disfonksiyonu tesbit edilmedi. SDY sadece sudomotor aktiviteyi gösterdiği için OSS’nin tamamını değerlendirmede yetersiz bir yöntem olabilir. OSS disfonksiyonu FM’nin etyopatogenezinden ziyade FM’de gözlenen bazı kronik semptomlardan, eşlik eden depresyon ve anksiyeteden sorumlu olabilir. FM hastalarının kronik semptom, anksiyete ve depresyon durumları da gözönünde bulundurularak, OSS’nin alt sistemlerini (kardiyovasküler refleks yol, sempatik kolinerjik aktivite gibi) inceleyen çalışmalar ile OSS’nin FM etyopatogenezindeki rolünü belirlemek mümkün olabilir.Türk Fiz Tıp Rehab Derg 2011;57:62-5.

🔖

Cite This Article

YILDIZ, N., ŞAHİN, Ö., YILDIZ, S., YAŞAR, M. F., KAPTANOĞLU, E. (2022). Fibromyaljide otonom sinir sistemi disfonksiyonunun değerlendirilmesi. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 57 - Sayı: 2, 62–65. https://ajindex.com/articles/629000

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 1990;33:160-72
  2. Ulas UH, Unlu E, Hamamcioglu K, Odabasi Z, Cakci A, Vural O. Dysautonomia in fibromyalgia syndrome: sympathetic skin responses and RR Interval analysis. Rheumatol Int 2006;26:383-7
  3. Qiao ZG, Vaeroy H, Morkrid L. Electrodermal and microcirculatory activity in patients with fibromyalgia during baseline, acoustic stimulation and cold pressor tests. J Rheumatol 1991;18:1383-9
  4. Unlu E, Ulas UH, Gurcay E, Tuncay R, Berber S, Cakci A, et al. Genital sympathetic skin responses in fibromyalgia syndrome. Rheumatol Int 2006;26:1025-30
  5. Vaeroy H, Qiao ZG, Morkrid L, Forre O. Altered sympathetic nervous system response in patients with fibromyalgia (fibrositis syndrome). J Rheumatol 1989;16:1460-5
  6. Thieme K, Turk DC. Heterogeneity of psychophysiological stress responses in fibromyalgia syndrome patients. Arthritis Res Ther 2006;8:R9
  7. Martinez-Lavin M. Management of dysautonomia in fibromyalgia. Rheum Dis Clin North Am 2002;28:379-87
  8. Martinez-Lavin M, Hermosillo AG. Autonomic nervous system dysfunction may explain the multisystem features of fibromyalgia. Semin Arthritis Rheum 2000;29:197-9
  9. Bengtsson A, Bengtsson M. Regional sympathetic blockade in primary fibromyalgia. Pain 1988;33:161-7
  10. Backman E, Bengtsson A, Bengtsson M, Lennmarken C, Henriksson KG. Skeletal muscle function in primary fibromyalgia. Effect of regional sympathetic blockade with guanethidine. Acta Neurol Scand 1988;77:187-91
  11. Elam M, Johansson G, Wallin BG. Do patients with primary fibromyalgia have an altered muscle sympathetic nerve activity? Pain 1992;48:371-5
  12. Zimmermann KP, Monga TN, Darouiche RO, Lawrence SA. Post-stroke autonomic nervous system function: Palmar sympathetic skin responses thirty or more days after cerebrovascular accident. Arch Phys Med Rehabil 1995;76:250-6
  13. Balci N, Balci MK, Beyazova M. Sympathetic skin response and R-R interval variation in diabetic patients. J Rheumatol Med Rehabil 1998;9:166-71
  14. Fagius J, Wallin BG. Sympathetic reflex latencies and conduction velocities in normal man. J Neurol Sci 1980;47:433-48
  15. Kucera P, Goldenberg Z, Kurca E. Sympathetic skin response: review of the method and its clinical use. Bratisl Lek Listy 2004;105:108-16
  16. Beck AT, Ward CH, Mendelso