Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2011 / Cilt: 57 - Sayı: 4

Primer ve sekonder huzursuz bacak sendromunun tedavisinde pregabalin:Üç olgu sunumu

Pregabalin in the treatment of primary and secondary restless legs syndrome: Three case reports

Pages
242–244
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, pregabalin may be a different treatment option for both idiopathic and secondary RLS.

📌 3 Key Takeaways

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Objective & Hypothesis:Restless legs syndrome (RLS) is a sensorimotor disease characterized by a sense of discomfort in the legs and involuntary movements of the legs before falling asleep and while resting.
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Key Findings & Data:The first two cases were considered secondary RLS, whereas the 3rd case was considered idiopathic RLS.
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Conclusion & Impact:In conclusion, pregabalin may be a different treatment option for both idiopathic and secondary RLS.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Restless legs syndrome (RLS) is a sensorimotor disease characterized by a sense of discomfort in the legs and involuntary movements of the legs before falling asleep and while resting. Dopamine receptor agonists, L-dopa, dopamine agonists, opioids, benzodiazepines, and gabapentin are commonly used in the treatment of RLS. However, a treatment model that is most effective for RLS has not yet been defined. In the present case series, the successful results of administering pregabalin for neuropathic pain and fibromyalgia syndrome (FMS) are presented in three patients with RLS. The first two cases were considered secondary RLS, whereas the 3rd case was considered idiopathic RLS. Iron deficiency anemia and FMS accompanied RLS in the 1st case (42- year-old female). Both FMS and RLS symptoms were improved with pregabalin. The 2nd case (38-year-old female) had type 1 diabetes mellitus (DM) and diabetic neuropathy. Both the symptoms of diabetic neuropathy and RLS were relieved with pregabalin. The 3rd case (48-year-old female) was idiopathic, and RLS has been completely taken under control with pregabalin treatment. In conclusion, pregabalin may be a different treatment option for both idiopathic and secondary RLS.

Özet

Huzursuz bacak sendromu (HBS) dinlenme sırasında ya da uykuya dalmadan önce bacaklarda istemsiz hareketler ve rahatsızlık hissiyle karakterize, sensorimotor bir hastalıktır. HBS’nin tedavisinde dopamin reseptör agonistleri, L-dopa, dopamin agonistleri, opioidler, benzodiyazepinler ve gabapentin yaygın olarak kullanılmaktadır. Bununla beraber, HBS’de çok etkili bir tedavi yöntemi belirlenmemiştir. Buradaki vaka serisinde HBS’li üç hastada nöropatik ağrı ve fibromiyalji sendromu (FMS) için pregabalin verilmesinin başarılı sonuçları sunulmaktadır. İlk iki vaka sekonder HBS, 3. vaka ise idiyopatik HBS olarak belirlenmiştir. İlk vakada (42 yaşında kadın hasta) HBS, demir eksikliği anemisi ve FMS ile birliktedir. FMS ve HBS semptomlarının her ikisi de pregabalinle rahatlamıştır. İkinci vaka (38 yaşında kadın hasta) tip-1 DM ve diyabetik nöropatiye sahiptir. Diyabetik nöropati ve HBS semptomları pregabalinle azalmıştır. Üçüncü vaka (48 yaşında kadın hasta) idiyopatik olup HBS semptomları pregabalin tedavisiyle kontrol altına alınmıştır. Sonuç olarak, pregabalin hem idiyopatik hem de sekonder HBS için farklı bir tedavi seçeneği olabilir.

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Cite This Article

KARATAY, S., YILDIRIM, K., OKUR, Ç. S. (2022). Primer ve sekonder huzursuz bacak sendromunun tedavisinde pregabalin:Üç olgu sunumu. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 57 - Sayı: 4, 242–244. https://ajindex.com/articles/628986

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