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Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2013 / Cilt: 59 - Sayı: 4

Platelet-rich plasma applications

Plateletten zengin plazma uygulamaları

Serdar KESİKBURUN
Bilge YILMAZ
Pages
338–344
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we present basic principles of PRP and its application in the musculoskeletal disorders.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Platelet-rich plasma (PRP) has been utilized with its effect of inducing tissue healing in medicine primarily in maxillofacial and cardiovascular surgery for 20 years; it has been started to be applied recently in the treatment of musculoskeletal injuries as well.
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Key Findings & Data:High concentrated autologous platelet injection grafts stimulate healing in chronic non-healing bone and soft tissue injuries.
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Conclusion & Impact:In this review, we present basic principles of PRP and its application in the musculoskeletal disorders.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Platelet-rich plasma (PRP) has been utilized with its effect of inducing tissue healing in medicine primarily in maxillofacial and cardiovascular surgery for 20 years; it has been started to be applied recently in the treatment of musculoskeletal injuries as well. Growth factors and bioactive proteins that platelets contain have a crucial role in the healing process. High concentrated autologous platelet injection grafts stimulate healing in chronic non-healing bone and soft tissue injuries. A limitation of repair mechanism has been indicated in chronic enthesopathies, rather than an inflammatory response. Instead of anti-inflammatory treatments that have conflicting long-term results, PRP injections are aimed to provide a promising alternative to surgery by promoting safe and natural healing in such cases resistant to therapy. In this review, we present basic principles of PRP and its application in the musculoskeletal disorders.

Özet

Plateletten zengin plazma (platelet rich plasma - PRP), doku iyileşmesiniarttırıcı etkisiyle başlıca maksillofasiyal ve kardiyovasküler cerrahi olmak üzere yaklaşık 20 senedir tıpta kullanılmakta olup, son dönemlerde kasiskelet sistemi yaralanmaları tedavisinde de uygulanmaya başlanmıştır. Plateletlerin içerdiği büyüme faktörleri ve biyoaktif proteinler iyileşmesürecinde önemli role sahiptirler. Yüksek konsantrasyonlu otolog platelet enjeksiyon greftleri ile kronik, iyileşmeyen kemik ve yumuşak dokuyaralanmalarında iyileşmenin stimüle edilmesi sağlanmaktadır. Kronik entezopatilerde, inflamatuvar bir yanıttan ziyade, tamir mekanizmalarındayetersizlik olduğu gösterilmiştir. Uzun dönem sonuçları konusunda çekinceler bulunan antiinflamatuvar tedaviler yerine kullanılan PRPenjeksiyonları ile doğal iyileşmeyi arttırarak kalıcı tedavi amaçlanmaktadır.PRP, dirençli entezopati vakalarında cerrahi öncesi bir alternatif olarak öneçıkmaktadır. Bu derlemede, PRP’nin temel prensipleri ve kas iskelet sistemihastalıklarında uygulama alanları hakkındaki bilgiler sunulmaktadır.

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Cite This Article

KESİKBURUN, S., YILMAZ, B. (2022). Platelet-rich plasma applications. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 59 - Sayı: 4, 338–344. https://ajindex.com/articles/628864

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