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Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2013 / Cilt: 59 - Sayı: 1

Romatoid artritte serum melatonin düzeyleri

Melatonin serum levels in rheumatoid arthritis

Akın ERDAL
Mahir UĞUR
Kazım ŞENEL
Meltem MELİKOĞLU ALKAN
Tuba BAYKAL
Hamit Hakan ALP
Pages
42–44
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The Mann-Whitney U-test was used to compare the data between the two groups.Results: MLT concentrations were significantly higher in RA patients thanin the controls (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Recent studies suggest that endogenous melatonin (MLT)production might play a role in the etiology of rheumatoid arthritis (RA).However, the role of MLT in RA pathogenesis remains unclear.
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Key Findings & Data:This studywas performed to determine MLT serum levels in RA patients.Materials and Methods: Twenty nine patients with RA and in 25 age- andsex-matched healthy controls were included in our study.
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Conclusion & Impact:The Mann-Whitney U-test was used to compare the data between the two groups.Results: MLT concentrations were significantly higher in RA patients thanin the controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Recent studies suggest that endogenous melatonin (MLT)production might play a role in the etiology of rheumatoid arthritis (RA).However, the role of MLT in RA pathogenesis remains unclear. This studywas performed to determine MLT serum levels in RA patients.Materials and Methods: Twenty nine patients with RA and in 25 age- andsex-matched healthy controls were included in our study. Blood samplesof the participants collected at 8AM. MLT was measured by enzyme-linkedimmunosorbent assay (ELISA). The MLT levels of the patients with RAwere compared with healthy age- and sex-matched controls. The Mann-Whitney U-test was used to compare the data between the two groups.Results: MLT concentrations were significantly higher in RA patients thanin the controls (p

Özet

Amaç: Son çalışmalar endojen melatonin (MLT) üretiminin romatoid artrit (RA) etyolojisinde rol oynayabileceğini ileri sürmektedir. Ancak MLT’nin RA patogenezindeki rolü açık değildir. Bu çalışma RA’lı hastalarda MLT düzeylerini belirlemek için düzenlenmiştir. Gereç ve Yöntem: Çalışmamıza 29 RA hastası ile yaş ve cins olarak eşleştirilmiş 25 sağlıklı kontrol dahil edildi Katılımcıların kan örnekleri sabah 8:00’da alındı. MLT enzyme-linked immunosorbent assay (ELISA) yöntemiyle ölçüldü. RA hastalarının MLT düzeyleri yaş ve cins olarak eşleştirilmiş kontroller ile karşılaştırıldı. Gruplar arasındaki verilerin karşılaştırılmasında Mann-Whitney U test kullanıldı. Bulgular: MLT düzeyleri RA hastalarında kontrol grubundan anlamlı olarak daha yüksekti (p

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Cite This Article

ERDAL, A., UĞUR, M., ŞENEL, K., ALKAN, M. M., BAYKAL, T., ALP, H. H. (2022). Romatoid artritte serum melatonin düzeyleri. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 59 - Sayı: 1, 42–44. https://ajindex.com/articles/628853

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