Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2013 / Cilt: 59 - Sayı: 3

Arthritis at advanced age: Rheumatoid arthritis and differential diagnosis

İleri yaşta artrit: Romatoid artrit ve ayırıcı tanısı

Pages
242–249
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the epidemiologicaland clinical features, laboratory findings, radiological characteristics, anddifferential diagnosis of EORA are discussed along with the associatedtreatment difficulties and recently reported alternative therapy options.Turk J Phys Med Rehab 2013;59:242-9.

📌 3 Key Takeaways

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Objective & Hypothesis:In recent decades, the prevalence of rheumatoid arthritis (RA) hasgradually decreased, but the age at onset has increased.
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Key Findings & Data:Currently, it isthought that RA has become a disease of the elderly, and has taken itsimportant place in the category of inflammatory arthritis at advanced ages.Determining an accurate diagnose of elderly-onset RA (EORA) is not aseasy as diagnosing young-onset RA due to insufficient laboratory findingsand the presence of distinct clinical features.
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Conclusion & Impact:In this review, the epidemiologicaland clinical features, laboratory findings, radiological characteristics, anddifferential diagnosis of EORA are discussed along with the associatedtreatment difficulties and recently reported alternative therapy options.Turk J Phys Med Rehab 2013;59:242-9.
🔬Design:Review & Systematic Survey
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

In recent decades, the prevalence of rheumatoid arthritis (RA) hasgradually decreased, but the age at onset has increased. Currently, it isthought that RA has become a disease of the elderly, and has taken itsimportant place in the category of inflammatory arthritis at advanced ages.Determining an accurate diagnose of elderly-onset RA (EORA) is not aseasy as diagnosing young-onset RA due to insufficient laboratory findingsand the presence of distinct clinical features. Furthermore, the incidenceof malignant diseases leading to paraneoplastic arthritis also increaseswith advanced age. Moreover, the lack of a widely accepted algorithmto diagnose paraneoplastic arthritis, which usually appears as elderly-onset arthritis, is an ongoing problem. In this review, the epidemiologicaland clinical features, laboratory findings, radiological characteristics, anddifferential diagnosis of EORA are discussed along with the associatedtreatment difficulties and recently reported alternative therapy options.Turk J Phys Med Rehab 2013;59:242-9.

Özet

Son 50 yılda romatoid artrit (RA) prevalansı giderek azalırken, hastalığın başlangıç yaşı gün geçtikçe yükselmektedir. Bu nedenle de RAnın ileri yaşın hastalığı haline geldiği düşünülmektedir. İleri yaşta enflamatuvarartritler içerisinde RAnın çok önemli bir yeri bulunmaktadır. Ancak yaşlı başlangıçlı romatoid artritte (YBRA), genç yaşa göre laboratuvar bulgularının yetersizliği, klinik tablonun farklı özelliklerinin bulunması, RA tanısı konulmasını güçleştirmektedir. İleri yaşta malign hastalıkların ve buna bağlı gelişebilecek paraneoplastik artritlerin görülme sıklığı artar. İleri yaş başlangıçlı artritlerde paraneoplastik artritler için yaygın kabul görmüş bir ayırıcı tanı algoritmasının olmaması da önemli bir sorun olmaya devam etmektedir. Bu derlemede YBRAnın epidemiyolojik, klinik ve radyolojik özellikleri, laboratuvar bulguları ve diğer ileri yaşta görülebilecek artrit tablolarından ayırıcı tanısı tartışılırken, ileri yaşta RAnın tedavisindeki zorluklar ve son yıllarda bildirilmiş öncelikli tedavi seçenekleri sunulmuştur. Türk Fiz T p Re­hab Derg 2013;59:242-9.

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Cite This Article

KİBAR, S., ERGİN, E. S. (2022). Arthritis at advanced age: Rheumatoid arthritis and differential diagnosis. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 59 - Sayı: 3, 242–249. https://ajindex.com/articles/628850

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