Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2016 / Cilt: 62 - Sayı: 2

Zoledronik asit infüzyonu sonrası gelişen inme: Tedavinin yan etkisi mi tesadüf mü?

Stroke following zoledronic acid infusion: effect of treatment or coincidence?

Pages
170–173
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case report highlights the possibility of zoledronic acid infusion-induced stroke with unusual side effects in geriatric patients

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Zoledronic acid is a parenteral aminobisphosphonate which is administered annually in the treatment of osteoporosis.
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Key Findings & Data:The most common side effects include post-dose reaction, renal dysfunction, and mild to moderate hypocalcemia.
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Conclusion & Impact:This case report highlights the possibility of zoledronic acid infusion-induced stroke with unusual side effects in geriatric patients
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Zoledronic acid is a parenteral aminobisphosphonate which is administered annually in the treatment of osteoporosis. It is an alternative to oral bisphosphonates, particularly in elderly patients with multiple comorbidities, because of its efficacy and intravenous route of administration. The most common side effects include post-dose reaction, renal dysfunction, and mild to moderate hypocalcemia. In this article, we report a 67-year-old male case of stroke during osteoporosis treatment of zoledronic acid within a day. Stroke development may be a coincidence, as the patient had stroke history and other risk factors for recurrent stroke. This case report highlights the possibility of zoledronic acid infusion-induced stroke with unusual side effects in geriatric patients

Özet

Zoledronik asit, osteoporoz tedavisinde yıllık olarak uygulanan parenteral bir aminobisfosfonattır. Özellikle birden fazla komorbiditesi olan yaşlı hastalarda, etkinliği ve intravenöz yolla uygulanmasından dolayı oral bifosfonatlara alternatiftir. En sık görülen yan etkileri doz sonrası reaksiyon, böbrek fonksiyon bozukluğu ve hafif ila orta şiddette hipokalsemidir. Bu yazıda zoledronik asit ile osteoporoz tedavisi sırasında bir gün içinde inme gelişen 67 yaşında bir erkek olgu sunuldu. Hastanın inme öyküsü ve tekrarlayan inme için diğer risk faktörleri olduğundan, inme gelişimi bir tesadüf olabilir. Bu olgu, geriatrik hastalarda olağan dışı yan etkiler ile zoledronik asit infüzyonuna bağlı inme olasılığına dikkat çekmektedir

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Cite This Article

ÇELİK, C., EROL, A. M., YALBUZDAĞ, S. A., ŞENTÜRK, B. (2022). Zoledronik asit infüzyonu sonrası gelişen inme: Tedavinin yan etkisi mi tesadüf mü?. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 62 - Sayı: 2, 170–173. https://ajindex.com/articles/628673

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