Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2016 / Cilt: 62 - Sayı: 4

Progresif subakut kombine dejenerasyon: B12 vitamini tedavisinin bırakılmasıyla oluşan şiddetli bir nüks olgusu

Progressive subacute combined degeneration: a severe relapse with discontinuation of vitamin B12 treatment

Pages
369–372
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Following the discontinuation of treatment, we took the patient admitted to our clinic with spastic paraplegia to the inpatient physical therapy program and we applied B12 replacement; we follow-up the patient who can ambulate with the aid of a walker upon discharge

📌 3 Key Takeaways

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Objective & Hypothesis:Subacute combined degeneration is a rare clinical manifestation characterized by dysesthesia, deep sensory impairment and spastic paraparesis.
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Key Findings & Data:A 62-year-old male patient was admitted to the outpatient clinic with the complaint of difficulty in walking.
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Conclusion & Impact:Following the discontinuation of treatment, we took the patient admitted to our clinic with spastic paraplegia to the inpatient physical therapy program and we applied B12 replacement; we follow-up the patient who can ambulate with the aid of a walker upon discharge
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Subacute combined degeneration is a rare clinical manifestation characterized by dysesthesia, deep sensory impairment and spastic paraparesis. A 62-year-old male patient was admitted to the outpatient clinic with the complaint of difficulty in walking. We detected he had position and vibration loss in all extremities, bilateral weakness in legs, spasticity and increase in deep tendon reflexes. History of the patient revealed that he was previously examined in a neurology clinic for sensory disturbance and his complaints declined after vitamin B12 deficiency was detected and treated. Following the discontinuation of treatment, we took the patient admitted to our clinic with spastic paraplegia to the inpatient physical therapy program and we applied B12 replacement; we follow-up the patient who can ambulate with the aid of a walker upon discharge

Özet

Subakut kombine dejenerasyon dizestezi, derin duyu bozukluğu ve spastik parapareziyle karakterize nadir bir klinik tablodur. Altmış iki yaşında erkek hasta polikliniğe yürüme güçlüğü yakınmasıyla başvurdu. Tüm ekstremitelerde pozisyon ve vibrasyon kaybı, bacaklarda iki taraflı güçsüzlük, spastisite ve derin tendon reflekslerinde artış saptandı. Hastanın öyküsünden duyusal yakınmalar nedeniyle daha önce nöroloji kliniğinde incelendiği, B12 vitamini eksikliği saptanarak tedavi uygulandığı ve yakınmalarının gerilediği öğrenildi. Tedaviyi bırakmasının ardından spastik parapleji tablosu ile polikliniğimize başvuran hasta yatarak fizik tedavi programına alındı ve B12 replasmanı uygulandı, taburculuğunda walker ile ambule olabilen olgu takibe alındı

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Cite This Article

BOY, F. N. S., ÖZKAN, F. Ü., KAYSIN, M. Y., AKTAŞ, İ., ÜSTÜN, I. (2022). Progresif subakut kombine dejenerasyon: B12 vitamini tedavisinin bırakılmasıyla oluşan şiddetli bir nüks olgusu. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 62 - Sayı: 4, 369–372. https://ajindex.com/articles/628668

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References (12)

  1. Briani C, Dalla Torre C, Citton V, Manara R, Pompanin S, Binotto G, et al. Cobalamin deficiency: clinical picture and radiological findings. Nutrients 2013;5:4521-39
  2. Cabrerizo-García JL, Sebastián-Royo M, Montes N, ZalbaEtayo B. Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency. Sao Paulo Med J 2012;130:259-62
  3. Green R, Kinsella LJ. Current concepts in the diagnosis of cobalamin deficiency. Neurology 1995;45:1435-40
  4. Healton EB, Savage DG, Brust JC, Garrett TJ, Lindenbam J. Neurologic aspects of cobalamin deficiency. Medicine (Baltimore) 1991;70:229-45
  5. Lindenbaum J, Healton EB, Savage DG, Brust JC, Garrett TJ, Podell ER, et al. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med 1988;318:1720-8
  6. Matchar DB, McCrory DC, Millington DS, Feussner JR. Performance of the serum cobalamin assay for diagnosis of cobalamin deficiency. Am J Med Sci 1994;308:276-83
  7. Berg RL, Shaw GR. Laboratory evaluation for vitamin B12 deficiency: the case for cascade testing. Clin Med Res 2013;11:7-15
  8. Larner AJ. Visual failure caused by vitamin B12 deficiency optic neuropathy. Int J Clin Pract 2004;58:977-8
  9. Bou-Haidar P, Peduto AJ, Karunaratne N. Differential diagnosis of T2 hyperintense spinal cord lesions: part B. J Med Imaging Radiat Oncol 2009;53:152-9
  10. Ravina B, Loevner LA, Bank W. MR findings in subacute combined degeneration of the spinal cord: a case of reversible cervical myelopathy. AJR Am J Roentgenol 2000;174:863-5
  11. Larner AJ, Zeman AZ, Allen CM, Antoun NM. MRI appearances in subacute combined degeneration of the spinal cord due to vitamin B12 deficiency. J Neurol Neurosurg Psychiatry 1997;62:99-100
  12. Katsaros VK, Glocker FX, Hemmer B, Schumacher M. MRI of spinal cord and brain lesions in subacute combined degeneration. Neuroradiology 1998;40:716-9.