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Journals / Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi / 2016 / Cilt: 62 - Sayı: 1

Omurilik yaralanması D vitamini eksikliği için bir risk faktörü müdür?

Is spinal cord injury a risk factor for vitamin D deficiency?

Neşe ÖZGİRGİN
Özlem TAŞOĞLU
Engin KOYUNCU
Didem YENİGÜN
Güldal Funda NAKİPOĞLU YÜZER
Pages
57–63
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Therefore, serum 25(OH)D levels should be analyzed on a routine basis in SCI patients and adequate supplementation should be performed in case of deficiency or insufficiency

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The aim of this study was to investigate whether spinal cord injury (SCI) is a risk factor for vitamin D deficiency.Patients and methods: A total of 125 patients with SCI as the patient group and 142 patients with neurologically intact patients as the control group admitted to the inpatient or outpatient clinics of our Physical Medicine and Rehabilitation Hospital between January 2013 and December 2014 were included in the study.
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Key Findings & Data:Serum 25-hydroxyvitamin D [25(OH)D] levels >30 ng/mL were accepted as normal, 20 to 30 ng/mL as insufficiency, and 0.005).
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Conclusion & Impact:Therefore, serum 25(OH)D levels should be analyzed on a routine basis in SCI patients and adequate supplementation should be performed in case of deficiency or insufficiency
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: The aim of this study was to investigate whether spinal cord injury (SCI) is a risk factor for vitamin D deficiency.Patients and methods: A total of 125 patients with SCI as the patient group and 142 patients with neurologically intact patients as the control group admitted to the inpatient or outpatient clinics of our Physical Medicine and Rehabilitation Hospital between January 2013 and December 2014 were included in the study. Data were retrospectively analyzed using the patient’s electronic medical records. Serum 25-hydroxyvitamin D [25(OH)D] levels >30 ng/mL were accepted as normal, 20 to 30 ng/mL as insufficiency, and 0.005). The median serum 25(OH)D level of the SCI group was 12.6 ng/mL and 14.4 ng/mL of the control group. A total of 95.2% of SCI patients and 95% of the controls were vitamin D deficient or insufficient. Serum 25(OH)D levels in the study group were statistically significantly lower than the control group (p=0.006), although it did not reach clinical significance. In both groups, serum 25(OH)D levels were independent from sex and blood sample collection season (p>0.05). Only ambulation status of SCI patients was found to be a significant factor affecting serum 25(OH)D levels in SCI group.Conclusion: Although it is difficult to conclude that SCI is a risk factor for vitamin D deficiency or insufficiency based on the results of our study, vitamin D insufficiency and deficiency are common among non-ambulated SCI patients, in particular. Therefore, serum 25(OH)D levels should be analyzed on a routine basis in SCI patients and adequate supplementation should be performed in case of deficiency or insufficiency

Özet

Amaç: Bu çalışmada omurilik yaralanmasının (OY) D vitamini eksikliği için risk faktörü olup olmadığı araştırıldı.Hastalar ve yöntemler: Çalışmaya Ocak 2013 - Aralık 2014 tarihleri arasında Fizik Tedavi ve Rehabilitasyon Hastanemizin yatan hasta veya polikliniklerine başvuran 125 OY'li hasta hasta grubu olarak ve nörolojik olarak sağlam 142 hasta kontrol grubu olarak alındı. Hastaların elektronik tıbbi kayıtları kullanılarak veriler retrospektif olarak incelendi. Serum 25-hidroksivitamin D [25(OH)D] düzeyi >30 ng/mL normal, 20-30 arası yetersizlik ve 0.005). Omurilik yaralanması olan grupta medyan serum 25(OH)D düzeyi 12.6 ng/mL ve kontrol grubunda 14.4 ng/mL olarak saptandı. Omurilik yaralanması olan hastaların toplam %95.2'sinde ve kontrollerin %95'inde D vitamini eksikliği veya yetersizliği vardı. Çalışma grubunda serum 25(OH)D düzeyleri, kontrol grubuna kıyasla, istatistiksel olarak anlamlı düzeyde daha düşük olmasına karşın (p=0.006), bu fark klinik olarak anlamlı değildi. Her iki grupta da, serum 25(OH)D düzeyleri cinsiyet ve kan örneği alınma mevsiminden bağımsızdı (p>0.05). Yalnızca OY hastalardaki ambulasyon durumu, serum 25(OH)D düzeylerini etkileyen anlamlı bir faktördü.Sonuç: Çalışma bulgularımıza göre OY'nin D vitamini eksikliği veya yetersizliğinin bir risk faktörü olduğu sonucuna varılması güç olmakla birlikte, D vitamini yetersizliği veya eksikliği, özellikle ambule olmayan OY'li hastalarda yaygındır. Bu nedenle, OY'li hastalarda serum 25(OH)D düzeyleri rutin olarak incelenmeli ve eksiklik veya yetersizlik durumunda gerekli destek verilmelidir

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Cite This Article

ÖZGİRGİN, N., TAŞOĞLU, Ö., KOYUNCU, E., YENİGÜN, D., YÜZER, G. F. N. (2022). Omurilik yaralanması D vitamini eksikliği için bir risk faktörü müdür?. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, Cilt: 62 - Sayı: 1, 57–63. https://ajindex.com/articles/628656

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