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Journals / Türkiye Çocuk Hastalıkları Dergisi / 2017 / Cilt: 11 - Sayı: 1

Traumatic Hyphema Successfully Treated with Recombinant Factor VIIa in Glanzmann Thrombasthenia with Platelet

Trombosit Refrakterliği Olan Glanzmann Trombastenili Hastada Travmatik Hifemanın Rekombinan Faktör VIIa ile Başarılı Tedavisi

Neşe YARALI
Abdurrahman KARA
Bahattin TUNÇ
İkbal OK BOZKAYA
Pages
74–76
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we report a case of GT with traumatic hyphema who was successfully treated with rFVIIa

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Glanzmann thrombasthenia (GT) is a congenital disorder of platelet aggregation characterized by a lifelong bleeding tendency.
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Key Findings & Data:Standard therapy consists of platelet transfusions; however repeated transfusions may result in antiplatelet antibodies and platelet refractoriness.
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Conclusion & Impact:Here we report a case of GT with traumatic hyphema who was successfully treated with rFVIIa
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Glanzmann trombastenisi · Hifema · Trombosit refrakterliği

Abstract

Glanzmann thrombasthenia (GT) is a congenital disorder of platelet aggregation characterized by a lifelong bleeding tendency. Standard therapy consists of platelet transfusions; however repeated transfusions may result in antiplatelet antibodies and platelet refractoriness. Recombinant activated factor VII (rFVIIa) is an effective alternative therapy in GT patients, particularly in those with antiplatelet antibodies and/or platelet refractoriness. Ocular manifestations of GT are very rare. Here we report a case of GT with traumatic hyphema who was successfully treated with rFVIIa

Özet

Glanzmann trombastenisi (GT) yaşam boyu kanamaya yatkınlıkla karakterize olan trombosit agregasyonunun kalıtımsal bozukluğudur. Glanzmann Trombastenisinin göz bulgularıyla nadiren karşılaşılır. Standart tedavi trombosit transfüzyonudur; bununla birlikte tekrarlanan transfüzyonlar trombosite karşı antikor oluşumu ve trombosit refrakterliği ile sonuçlanmaktadır. Rekombinan aktif faktör VIIa (rFVIIa) trombosit antikoru ve/veya trombosit refrakterliği olan GT hastalarda efektif alternatif bir tedavidir. Burada rFVIIa ile başarılı bir şekilde tedavi edilen travmatik hifeması olan GT’li bir hastayı sunduk.

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Cite This Article

YARALI, N., KARA, A., TUNÇ, B., BOZKAYA, İ. O. (2022). Traumatic Hyphema Successfully Treated with Recombinant Factor VIIa in Glanzmann Thrombasthenia with Platelet. Türkiye Çocuk Hastalıkları Dergisi, Cilt: 11 - Sayı: 1, 74–76. https://ajindex.com/articles/627722

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