Journals / Türkiye Acil Tıp Dergisi / 2008 / Cilt: 8 - Sayı: 1

Analysis of 13 patients with hypokalemic periodic paralysis

Hipokalemik periyodik paralizili 13 olgunun analizi

Pages
1–5
Publication Date
2022-11-03
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In our study, the most common secondary cause was thyrotoxicosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Hypokalemic periodic paralysis is characterized by intermittent episodes of muscle weakness or paralysis.
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Key Findings & Data:Materials and Methods: In this retrospective study, 13 patients with hypokalemic periodic paralysis were evaluated according to the etiologies, clinical and laboratory findings in the light of the literature.
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Conclusion & Impact:In our study, the most common secondary cause was thyrotoxicosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Hypokalemic periodic paralysis is characterized by intermittent episodes of muscle weakness or paralysis. The attacks may occur everyday or once a year and may last for a few hours to several days. The serum potassium level is low during the attack. However, the serum potassium levels are normal between two attacks. In this study, we aimed to point out the clinical and etiological features of hypokalemic periodic paralysis. Materials and Methods: In this retrospective study, 13 patients with hypokalemic periodic paralysis were evaluated according to the etiologies, clinical and laboratory findings in the light of the literature. Results: In this study; thirteen patients (11 males, 2 females; mean age 31.1±11.2 years) were evaluated. The most common etiological cause was thyrotoxic hypokalemic periodic paralysis. The other causes were familial factors, distal renal tubular acidosis, and gastroenteritis respectively. Thyrotoxicosis was diagnosed in 2 cases during the first hypokalemic attack. Six cases had already hyperthyroidism diagnosis and had been taken therapy for hyperthyroidism. Conclusion: Hypokalemic periodic paralysis occurs depending on primary and secondary etiologies. In our study, the most common secondary cause was thyrotoxicosis.

Özet

Gi r i ş: Hipokalemik periyodik paralizi, periyodik kas güçsüzlüğü veya paralizi atakları ile kendini gösteren bir hastalı ktır. Ataklar günde veya yılda bir olup birkaç saat veya birkaç gün sürebilir. Atak sırasında serumdaki potasyum seviyesi düşüktür. Ancak ataklar arasında serum potasyum seviyeleri normaldir. Bu yazıdaki amaç, hipokalemik periyodik paralizinin klinik ve etiyolojik özelliklerine dikkat çekmektir. Gereç ve Yöntem: Bu geriye dönük çalışmada, jeneralize güçsüzlük yakınması ile acil polikliniğe başvuran ve hipokalemik periyodik paralizi olarak tanınan 13 olgu etyoloji, klinik ve laboratuvar özelliklerine göre literatür ışığında tartışıldı. Bulgular: On bir erkek, iki kadından oluşan olgu serisinde olguların yaş ortalaması 31.1±11.2 idi. En sık etyolojik neden tirotoksikoz olup diğer nedenler sırasıyla familyal nedenler, distal renal tubuler asidoz ve gastroenterit idi. Tirotoksikoz tanısı 2 olguda ilk hipokalemik atak sırasında konuldu. Altı olgu daha önce hipertiroidizm tanısı almış ve tedavi gören olgular olup bu olgular güçsüzlük yakınması ile kliniğimize başvurmuşlardı. Sonuç: Hipokalemik periyodik paralizi birincil ve ikincil nedenlere bağlı olarak ortaya çıkar. Bizim çalışmamızda ikincil periyodik paralizinin en sık tirotoksikoza bağlı olarak meydana geldiği saptanmıştır.

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Cite This Article

KOÇ, F. (2022). Analysis of 13 patients with hypokalemic periodic paralysis. Türkiye Acil Tıp Dergisi, Cilt: 8 - Sayı: 1, 1–5. https://ajindex.com/articles/626109

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