Journals / Türkiye Acil Tıp Dergisi / 2014 / Cilt: 14 - Sayı: 4

Methemoglobinemia Güzelliğin Bedeli; Prilokaine Bağlı Gelişen Methemoglobinemi Olgusu

Cost of Beauty; Prilocaine Induced Methemoglobinemia

Pages
185–187
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Emergency physician should consider methemoglobinemia in presentation of dispnea and cyanosis after injection of prilocaine.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Prilocaine induced methemoglobinemia is a rare entity.
📊
Key Findings & Data:A 30-year-old female presented to Emergency Department with headache, dispnea and cyanosis.
💡
Conclusion & Impact:Emergency physician should consider methemoglobinemia in presentation of dispnea and cyanosis after injection of prilocaine.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Prilocaine induced methemoglobinemia is a rare entity. In the pres- ent paper, the authors aim to draw attention to the importance of this rare condition by reporting this case. A 30-year-old female presented to Emergency Department with headache, dispnea and cyanosis. The patient has a history of 1000-1200 mg of prilocaine subcutaneous injection for hair removal at a beauty center, 5 hours ago. Tension arterial: 130/73 mmHg, pulse: 103/minute, body tem- perature: 37 °C and respiratory rate: 20/minute. The patient had ac- ral and perioral cyanosis. Methemoglobin was measured 14.1% in venous blood gas test. The patient treated with 3 gr ascorbic acid intravenously. The patient was discharged free of symptoms after 48 hours of observation. Emergency physician should consider methemoglobinemia in presentation of dispnea and cyanosis after injection of prilocaine.

Özet

Prilokaine bağlı gelişen methemoglobinemi nadir görülen bir du- rumdur. Bu yazıda epilasyon öncesi kullanılan prilokaine sekonder gelişen methemoglobinemi olgusunu sunarak nadir görülen bu durumun önemine işaret etmek istiyoruz. Otuz yaşında kadın acil servise baş ağrısı, dispne ve siyanoz şikayetleri ile başvurdu. Hasta- ya beş saat öncesinde bir güzellik merkezinde epilasyon öncesinde yaklaşık 1000-1200 mg prilokain subkutan enjeksiyonu yapıldığı öğrenildi. Başvuruda kan basıncı 130/73 mmHg, nabız 103/dk, vü- cut ısısı 37 °C ve solunum sayısı 20/dk olarak kaydedilmişti. Hasta- nın akral siyanozu belirgindi. Venöz kan gazında methemoglobin düzeyi %14.1 olarak ölçüldü. Hastaya 3 g intravenöz askorbik asit uygulandı. Tedavi sonrası semptomları gerileyen ve komplikasyon geliştirmeyen hasta 48 saat sonra taburcu edildi. Acil servis doktor- ları, prilokain enjeksiyonu sonrası gelişen dispne ve siyanoz ayırıcı tanısında mutlaka methemoglobinemiyi akla getirmelidirler.

🔖

Cite This Article

AKSEL, G., KILIÇLI, E., ÖZEL, B. A., ARTUK, D. S., KAVALCI, C. (2022). Methemoglobinemia Güzelliğin Bedeli; Prilokaine Bağlı Gelişen Methemoglobinemi Olgusu. Türkiye Acil Tıp Dergisi, Cilt: 14 - Sayı: 4, 185–187. https://ajindex.com/articles/625930

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Honig GR. Hemoglobin disorder. In: Behrman RE, Kleigman RM, Jenson HB, editors. Nelson textbook of pediatrics. Phila- delpiha: Saunders; 2004. p. 1478-88
  2. Aygencel SG, Akinci E, Pamukcu G. Prilocaine induced methe- moglobinemia. Saudi Med J 2006;27:111-3
  3. Tabel Y, Sandikkaya A, Gungor S, Ozgen U. Methemoglobin- emia after injection of prilocaine for pre-medication of cir- cumcision. [Article in Turkish] J Dicle Med School 2009:36:53- 4. Coleman MD, Coleman NA. Drug-induced methaemoglobi- naemia. Treatment issues. Drug Saf 1996;14:394-405
  4. Kreutz RW, Kinni ME. Life-threatening toxic methemoglobin- emia induced by prilocaine. Oral Surg Oral Med Oral Pathol 1983;56:480-2
  5. Warren RE, Van de Mark TB, Weinberg S. Methemoglobinemia induced by high doses of prilocaine. Oral Surg Oral Med Oral Pathol 1974;37:866-71
  6. Guay J. Methemoglobinemia related to local anesthetics: a summary of 242 episodes. Anesth Analg 2009;108:837-45
  7. Mansouri A, Lurie AA. Concise review: methemoglobinemia. Am J Hematol 1993;42:7-12
  8. Akıncı E, Yüzbaşıoğlu E, Aslay S, Coşkun F. Incidence of meto- clopramide-induced methemoglobinemia. Turk J Emerg Med 2011;11:49-53
  9. Ryoo S, Sohn Ch, Oh B, Kim W, Lim K. A case of severe methe- moglobinemia caused by hair dye poisoning. Hum Exp Toxi- col 2014;33:103-5
  10. Gülgün M, Kul M, Sarıcı S. Prilocaine-induced methemoglo- binemia: report of two cases and review of literature. Erciyes Tıp Dergisi (Erciyes Medical Journal) 2007;29:322-5
  11. Öztürk E, Aktaş BT, Öztarhan K, Adal E. Lokal anestezik uygulaması sonrası gelişen methemoglobinemi. Jopp Rerg 2010;2:46-8
  12. Aydogan M, Toprak DG, Turker G, Zengin E, Arisoy ES, Go- kalp AS. Intravenous ascorbic acid treatment in prilocaine- induced methemoglobinemia: report of two cases. [Article in Turkish] Cocuk Sagligi ve Hastaliklari Dergisi 2005;48:65-8. 14. den Boer PJ, Bleeker WK, Rigter G, Agterberg J, Stekkinger P, Kannegieter LM, et al. Intravascular reduction of methemo- globin in plasma of the rat in vivo. Biomater Artif Cells Immo- bilization Biotechnol 1992;20:647-50
  13. Ballin A, Brown EJ, Koren G, Zipursky A. Vitamin C-in- duced erythrocyte damage in premature infants. J Pediatr 1988;113:114-20
  14. Tekbas G, Oguzkurt L, Ozkan U, Gurel K. Prilocain-induced methemoglobinemia after endovenous laser ablation. J Vasc Interv Radiol 2010;21:758-9.