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Journals / Türk Hijyen ve Deneysel Biyoloji Dergisi / 2001 / Cilt: 58 - Sayı: 2

Chronic effects of linear alkyl benzene sulphonate (LAS) given by oral route on the levels of glucose, total bilirubine and urea in serum and liver of rats

Ratlarda oral olarak verilen linear alkil benzen sulfonatın (LAS) serum ve karaciğerdeki üre, glukoz ve total bilirubin düzeyleri üzerine kronik etkilerinin araştırılması

Meryem ŞAKAR
Ahmet MENGİ
Pages
39–47
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was concluded that LAS in doses of 0.002 % (0.14 mg/kg) and 0.005 % (0.35 mg/kg) may be unimportant in rats because it created non-toxic chronic effects and chronic toxicologic effects of LAS for rats occur in doses of 0.01 % (0.7 mg/kg) and 0.03 % (2.1 mg/kg) and 120. days after the application.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, it was examined the chronic effects of Linear Alkyl Benzene Sulphonate (LAS) given by oral route, on the levels of glucose, total bilirubine and urea in serum and liver of rats.
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Key Findings & Data:In this study, it was examined the chronic effects of Linear Alkyl Benzene Sulphonate (LAS) given by oral route, on the levels of glucose, total bilirubine and urea in serum and liver of rats.
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Conclusion & Impact:It was concluded that LAS in doses of 0.002 % (0.14 mg/kg) and 0.005 % (0.35 mg/kg) may be unimportant in rats because it created non-toxic chronic effects and chronic toxicologic effects of LAS for rats occur in doses of 0.01 % (0.7 mg/kg) and 0.03 % (2.1 mg/kg) and 120. days after the application.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, it was examined the chronic effects of Linear Alkyl Benzene Sulphonate (LAS) given by oral route, on the levels of glucose, total bilirubine and urea in serum and liver of rats. It was concluded that LAS in doses of 0.002 % (0.14 mg/kg) and 0.005 % (0.35 mg/kg) may be unimportant in rats because it created non-toxic chronic effects and chronic toxicologic effects of LAS for rats occur in doses of 0.01 % (0.7 mg/kg) and 0.03 % (2.1 mg/kg) and 120. days after the application.

Özet

Bu araştırmada ratlara oral olarak verilen Linear Alkil Benzen Sülfonat (LAS)'ın serum ve karaciğerdeki glukoz, total bilirubin ve üre düzeyleri üzerine kronik etkileri incelenmiştir. Bu çalışmada LAS'ın %0.002 (0.14mg/kg)'lık ve %0.005 (0.35mg/kg)'lık dozlarının ratlarda kronik olarak herhangi bir toksisiteye neden olmayacağı ve ratlar için LAS'ın kronik etkilerinin %0.01 (0.7mg/kg) ile %0.03 (2.1mg/kg) dozlarında ve 120.günden itibaren gerçekleştiği sonucuna varılmıştır.

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Cite This Article

ŞAKAR, M., MENGİ, A. (2022). Chronic effects of linear alkyl benzene sulphonate (LAS) given by oral route on the levels of glucose, total bilirubine and urea in serum and liver of rats. Türk Hijyen ve Deneysel Biyoloji Dergisi, Cilt: 58 - Sayı: 2, 39–47. https://ajindex.com/articles/625277

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