Journals / Türk Hijyen ve Deneysel Biyoloji Dergisi / 2008 / Cilt: 65 - Sayı: 2

Scorpion antivenom production

Akrep antivenom üretimi

Pages
97–108
Publication Date
2022-11-03
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The protocol of scorpion antivenom production was explained in this study.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Scorpions do not harbor agents of disease but, they cause envenomations by stinging humans and animals, most of the time to protect themselves.
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Key Findings & Data:Plasma was separated from collected blood.
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Conclusion & Impact:The protocol of scorpion antivenom production was explained in this study.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Scorpions do not harbor agents of disease but, they cause envenomations by stinging humans and animals, most of the time to protect themselves. Scorpion antivenom treatment is still the only method used for therapy of scorpionism cases. Antivenom is produced by injecting a small amount of the venom into an animal such as horse, sheep, goat, or camel. These animals develop an immune response against the venom's active molecule. Antibodies produced in animal's blood were taken in regular intervals. Plasma was separated from collected blood. It purified by different chemical process and used to treat of scorpion stings. In Turkey, scorpion antivenom has been produced in Refik Saydam Hygiene Center since 1942. The protocol of scorpion antivenom production was explained in this study.

Özet

Akrepler hastalık etkenlerini taşımazlar, ancak çoğu zaman kendilerini korumak amacıyla, insan ve hayvanları sokarak zehirlenmeye neden olurlar. Skorpionizm vakalarının tedavisinde halen kullanılan tek metot akrep antivenom tedavisidir. Antivenom at, koyun, keçi veya deve gibi hayvanlara küçük miktarlarda venom enjeksiyonu ile üretilmektedir. Bu hayvanlarda venomun aktif molekülüne karşı immun bir yanıt gelişir. Hayvanların kanında üretilen antikorlar hayvanlardan düzenli aralıklarla alınır. Toplanan kandan plazma ayrılır. Farklı kimyasal yöntemlerle saflaştırılır ve akrep sokmalarının tedavisinde kullanılır. Türkiye'de, akrep antivenomu 1942 yılından beri Refik Saydam Hıfzısıhha Merkez Başkanlığı'nda üretilmektedir. Bu derlemede, akrep antivenom üretim protokolü hakkında bilgi verilmesi amaçlanmıştır.

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Cite This Article

ÖZKAN, Ö. (2022). Scorpion antivenom production. Türk Hijyen ve Deneysel Biyoloji Dergisi, Cilt: 65 - Sayı: 2, 97–108. https://ajindex.com/articles/625210

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