Journals / Türk Hijyen ve Deneysel Biyoloji Dergisi / 2012 / Cilt: 69 - Sayı: 2

Investigation of Francisella tularensis antibodies in dogs in Kars and Ankara Region

Kars ve Ankara Yöresine ait köpeklerde Francisella tularensis antikorlarının araştırılması

Pages
83–88
Publication Date
2022-11-05
DOI
—
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CONCLUSION: It was concluded that dogs may play a role at transmission of tularaemia to people, such studies would benefit for the elucidation of the epidemiology of the disease and should be increased of the number of them.

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Objective & Hypothesis:OBJECTIVE: Tularemia, is a zoonotic disease with a wide variety of hosts caused by Francisella tularensis, that affects many animal species including mammals, birds and insects.
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Key Findings & Data:METHODS: One hundred seventy one sheepdog blood serum samples from Kars region and 99 pet dog blood serum samples from Ankara region were examined in terms of F. tularensis antibodies with microagglutination test (MAT).
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Conclusion & Impact:CONCLUSION: It was concluded that dogs may play a role at transmission of tularaemia to people, such studies would benefit for the elucidation of the epidemiology of the disease and should be increased of the number of them.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Tularemia, is a zoonotic disease with a wide variety of hosts caused by Francisella tularensis, that affects many animal species including mammals, birds and insects. Small rodents are the natural hosts, and blood-sucking ectoparasites are the most important vectors. Sheep are the most susceptible species to tularemia in domestic animals. Dogs play an important role in the epidemiology of tularemia, both as a reservoir carrying of the bacteria and as a host of ticks. In this study it was aimed to investigate of F. tularensis antibodies in sheepdog from the Kars region and pet dog from the Ankara region. METHODS: One hundred seventy one sheepdog blood serum samples from Kars region and 99 pet dog blood serum samples from Ankara region were examined in terms of F. tularensis antibodies with microagglutination test (MAT). F. tularensis antigen containing 0.005% safranin-O was used as the test antigen. Antibody titer of 1/80 or higher was considered as diagnostic titer with MAT. RESULTS: F. tularensis antibody titers were found as 1/80 and above in total of 11 (4.07%) dogs including 9 (5.3%) sheepdogs and 2 (2.0%) pet dogs. These serum samples were examined with Brucella canis antigen and were found negative for brucellosis. The difference of F. tularensis antibodies incidence between sheepdogs and pet dogs was found statistically insignificant (p>0.05). CONCLUSION: It was concluded that dogs may play a role at transmission of tularaemia to people, such studies would benefit for the elucidation of the epidemiology of the disease and should be increased of the number of them.

Özet

AMAÇ: Tularemi, Francisella tularensis tarafından oluşturulan memeliler, kuşlar ve böcekler dahil birçok hayvan türünü etkileyen geniş konak çeşitliliğine sahip zoonotik bir hastalıktır. Tularemi için küçük kemiriciler doğal konakçı; kan emen ektoparazitler ise en önemli vektörlerdir. Evcil hayvanlar içerisinde tularemiye en duyarlı tür koyunlardır. Köpekler ise gerek bakteriyi taşımakla rezervuar olarak gerekse kenelere konakçılık yaparak tulareminin epidemiyolojisinde önemli rol oynarlar. Bu çalışmada; Kars Yöresine ait çoban köpekleri ve Ankara Yöresine ait pet köpeklerinde F. tularensis antikorlarının araştırılması amaçlanmıştır. YÖNTEMLER: Kars Yöresine ait 171 çoban köpeği ve Ankara yöresine ait 99 pet köpeğinin kan serum örneği F. tularensis antikorları yönünden mikroaglütinasyon testi (MAT) ile incelenmiştir. Test antijeni olarak %0,005 safranin-O içeren F. tularensis antijeni kullanılmıştır. MAT ile 1/80 ve üzeri antikor titresi tanısal titre olarak dikkate alınmıştır. BULGULAR: Çoban köpeklerinin dokuz (%5,3)ü ve pet köpeklerinin iki (%2,0)ı olmak üzere toplamda 11 (%4,1) köpekte 1/80 ve üzeri titrede F. tularensis antikoru saptanmıştır. Bu serum örnekleri Brucella canis antijeni ile incelenerek brusellozis yönünden negatif oldukları belirlenmiştir. Çoban köpekleri ve pet köpeklerinde F. tularensis antikorlarının görülme sıklığı arasındaki fark istatistiksel olarak önemsiz (p>0,05) bulunmuştur. SONUÇ: Tulareminin insanlara bulaşmasında köpeklerin rol oynayabileceği, hastalığın epidemiyolojisinin aydınlatılmasına yönelik bu tür çalışmaların yarar sağlayacağı ve sayılarının artırılması gerektiği kanısına varılmıştır.

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Cite This Article

MOR, N., ÇELEBİ, B., ÇELEBİ, Ö., BÜYÜK, F., ŞAHİN, M. (2022). Investigation of Francisella tularensis antibodies in dogs in Kars and Ankara Region. Türk Hijyen ve Deneysel Biyoloji Dergisi, Cilt: 69 - Sayı: 2, 83–88. https://ajindex.com/articles/625152

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