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Journals / Türk Hijyen ve Deneysel Biyoloji Dergisi / 2014 / Cilt: 71 - Sayı: 3

The effect of pine oil on the some alterations in liver tissue of experimental diabetes

Deneysel diyabetin karaciğer dokusunda oluşturduğu bazı değişiklikler üzerine çam yağının etkisi

Ökkeş YILMAZ
Ersin DEMİR
Pages
113–124
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

RESULTS: It was observed that MDA and total protein levels were significantly increased (p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: The present study was designed to evaluate the impact of pine oil on MDA (malondialdehyde), GSH (glutathione), total protein, fatty acid composition, ADEK vitamins, cholesterol and some sterols parameters in liver tissue of experimental diabetes in rats.
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Key Findings & Data:Diabetes induced in rats by a single intraperitoneal injection of streptozotocin (45 mg/kg). 1 mL/kg dose pine oil was intraperitoneally injected twice in a week to the streptozotocin (STZ) + pine oil (PO), and additionally 0.5 mL /500 mL dose of pine oil was added to drinking water of this group.
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Conclusion & Impact:RESULTS: It was observed that MDA and total protein levels were significantly increased (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: The present study was designed to evaluate the impact of pine oil on MDA (malondialdehyde), GSH (glutathione), total protein, fatty acid composition, ADEK vitamins, cholesterol and some sterols parameters in liver tissue of experimental diabetes in rats. METHODS: The rats were divided into three groups: control (C) streptozotocin (STZ), streptozotocin (STZ) + pine oil (PO) groups. Diabetes induced in rats by a single intraperitoneal injection of streptozotocin (45 mg/kg). 1 mL/kg dose pine oil was intraperitoneally injected twice in a week to the streptozotocin (STZ) + pine oil (PO), and additionally 0.5 mL /500 mL dose of pine oil was added to drinking water of this group. The experiment continued for eight weeks. RESULTS: It was observed that MDA and total protein levels were significantly increased (p

Özet

AMAÇ: Bu çalışma; deneysel diyabet oluşturulan sıçanlarda çam yağının karaciğer dokusunda yağ asidi bileşimi, malondialdehit (MDA), glutatyon (GSH), total protein, ADEK vitaminleri, kolesterol ve bazı sterol parametreleri üzerinde etkisinin araştırılması için tasarlandı. YÖNTEMLER: Sıçanlar; kontrol (K), streptozotosin (STZ) ve streptozotosin (STZ) + çam yağı (ÇY) olmak üzere üç grubu ayrıldı. STZ gruplarına intraperitoneal enjeksiyonla streptozotosin (45 mg/kg) verilerek diyabet oluşturuldu. Çam yağı grubundaki sıçanlara haftada iki gün 1 mL/kg dozunda intraperitoneal enjeksiyonla çam yağı ve ayrıca 0,5 mL çam yağı 500 mL içme suyuna ilave edilerek verildi. Bu uygulamalar sekiz hafta boyunca sürdürüldü. BULGULAR: Kontrol grubuna göre; STZ grubunun karaciğer dokusunda MDA ve total protein düzeyinin anlamlı bir şekilde (p

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Cite This Article

YILMAZ, Ö., DEMİR, E. (2022). The effect of pine oil on the some alterations in liver tissue of experimental diabetes. Türk Hijyen ve Deneysel Biyoloji Dergisi, Cilt: 71 - Sayı: 3, 113–124. https://ajindex.com/articles/625107

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