AI Summary & Key Takeaways
AI InsightHe was not able to take vasopressin because of side effects, but the treatment with cytosine arabinoside and idarubicine resulted in marked improvement of clinical and laboratory findings.
📌 3 Key Takeaways
Abstract
Central nervous system infiltration by leukemic cells is a well-known phenomenon. Clinical presentation and diagnosis differ, but the effective therapy is early chemotherapy with appropriate drugs. In this report, we describe a patient who, at the onset of acute myelomonocytic leukemia, presented with marked polyuria, polydipsia and laboratory findings consistent with diabetes insipidus. He was not able to take vasopressin because of side effects, but the treatment with cytosine arabinoside and idarubicine resulted in marked improvement of clinical and laboratory findings.
Özet
Santral sinir sisteminin, lösemik hücrelerle infiltrasyonu iyi bilinen bir kavramdır. Klinik yansıması ve teşhisi farklılık gösterse de, etkin tedavi erken ve uygun ilaçlarla yapılacak olan kemoterapi olmalıdır. Bu yazıda, poliüri, polidipsi ve laboratuvar bulguları ile diabetes insipidus düşünülen ve incelemeler sonucu akut myelomonositik lösemi tanısı alan bir olgu sunulmaktadır. Olgu, yan etkileri nedeni ile desmopressin kullanamamış, sitozin arabinosid ve idarubisinden oluşan kemoterapi protokolü ile belirgin klinik ve laboratuvar iyileşme sağlanmıştır.