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Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2013 / Cilt: 21 - Sayı: 2

Effects of mean platelet volume on survival of the patients undergoing below-knee bypass

Diz altı baypas yapılan hastalarda ortalama trombosit hacminin sağkalım üzerindeki etkileri

Berk ARAPİ
Caner ARSLAN
Berra Zümrüt TAN
Hayriye VEHİD ERTEM
Kamil Hasan TÜZÜN
Safa GÖDE
Kazım BEŞİRLİ
Pages
353–357
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The second MPV group (7.5 fl≤MPV≤9.4 fl) had longer survival than third MPV group (9.5 fl≤MPV≤11.4 fl) patients (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: This study aims to investigate the relationship of the mean platelet volume (MPV) values, risk factors, treatment protocols with the mortality in patients undergoing below-knee bypass.
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Key Findings & Data:Methods: A total of 117 patients (96 males, 21 females; mean age 60.6 years; range 45 to 84 years) who underwent belowknee bypass were enrolled in this study.
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Conclusion & Impact:The second MPV group (7.5 fl≤MPV≤9.4 fl) had longer survival than third MPV group (9.5 fl≤MPV≤11.4 fl) patients (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: This study aims to investigate the relationship of the mean platelet volume (MPV) values, risk factors, treatment protocols with the mortality in patients undergoing below-knee bypass. Methods: A total of 117 patients (96 males, 21 females; mean age 60.6 years; range 45 to 84 years) who underwent belowknee bypass were enrolled in this study. Patients with one of the risk factors at least including diabetes mellitus, hypertension, hyperlipidemia, smoking and obesity were accepted as highrisk patients. After surgery, patients were divided into four groups according to the MPV values. These groups were compared with each other in terms of survival time. Age, the amount of cigarette smoking, platelet count, treatment protocol, sex and risk status parameters were statistically analyzed.Results: There was no statistically significant difference in term of age (p=0.074), the amount of cigarette (p= 0.882) platelet count (p= 0.496), and treatment protocol (p=0.278) between survivors and ex-patient. No statistically significant difference was observed in terms of sex (p=0.303) and risk (p=0.550) parameters between the mortality groups. The second MPV group (7.5 fl≤MPV≤9.4 fl) had longer survival than third MPV group (9.5 fl≤MPV≤11.4 fl) patients (p

Özet

Amaç: Bu çalışmada diz altı baypas yapılan hastalardaki ortalama trombosit hacmi (OTH) değerleri, risk faktörleri ve tedavi protokollerinin mortalite ile olan ilişkisi araştırıldı. Çalışma planı: Diz altı baypas ameliyatı yapılan toplam 117 hasta (96 erkek, 21 kadın; ort. yaş 60.6 yıl; dağılım 45-84 yıl) çalışmaya alındı. Diyabet, hipertansiyon, hiperlipidemi, sigara ve obezite risklerinden en az birini taşıyan hastalar riskli olarak kabul edildi. Ameliyat sonrası hastalar OTH değerlerine göre dört gruba ayrıldı. Gruplar, sağkalım süreleri açısından birbirleriyle karşılaştırıldı. Yaş, sigara içme miktarı, trombosit sayısı, tedavi protokolü, cinsiyet ve risk durumu parametreleri de istatistiksel olarak incelendi.Bulgular: Halen hayatta olan ve kaybedilen hastalar arasında; yaş (p=0.074), sigara miktarı (p=0.882), trombosit sayısı (p=0.496) ve tedavi protokolü (p=0.278) açısından istatistiksel olarak anlamlı bir fark saptanmadı. Cinsiyet (p=0.303) ve risk (p=0.550) parametrelerine göre, mortalite grupları açısından istatistiksel olarak anlamlı bir farklılık gözlenmedi. İkinci OTH grubundaki (7.5 fl≤OTH≤9.4 fl) hastaların, üçüncü OTH grubundaki (9.5 fl≤OTH≤11.4 fl) hastalara kıyasla, anlamlı olarak daha uzun yaşadığı gözlendi (p

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Cite This Article

ARAPİ, B., ARSLAN, C., TAN, B. Z., ERTEM, H. V., TÜZÜN, K. H., GÖDE, S., BEŞİRLİ, K. (2022). Effects of mean platelet volume on survival of the patients undergoing below-knee bypass. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 21 - Sayı: 2, 353–357. https://ajindex.com/articles/624600

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References (15)

  1. Davì G, Patrono C. Platelet activation and atherothrombosis. N Engl J Med 2007;357:2482-94
  2. Michelson AD. Platelet function testing in cardiovascular diseases. Circulation 2004;110:e489-93
  3. Karpatkin S. Heterogeneity of human platelets. II. Functional evidence suggestive of young and old platelets. J Clin Invest 1969;48:1083-7
  4. Kamath S, Blann AD, Lip GY. Platelet activation: assessment and quantification. Eur Heart J 2001;22:1561-71
  5. Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 1996;7:157-61
  6. Papanas N, Symeonidis G, Maltezos E, Mavridis G, Karavageli E, Vosnakidis T, et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets 2004;15:475-8
  7. Huczek Z, Kochman J, Filipiak KJ, Horszczaruk GJ, Grabowski M, Piatkowski R, et al. Mean platelet volume on admission predicts impaired reperfusion and long-term mortality in acute myocardial infarction treated with primary percutaneous coronary intervention. J Am Coll Cardiol 2005;46:284-90
  8. Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. J Thromb Haemost 2010;8:148-56. doi: 10.1111/j.1538- 7836.2009.03584.x
  9. O’Malley T, Langhorne P, Elton RA, Stewart C. Platelet size in stroke patients. Stroke 1995;26:995-9
  10. Martin JF, Trowbridge EA, Salmon GL, Slater DN. The relationship between platelet and megakaryocyte volumes. Thromb Res 1982;28:447-59
  11. Berger JS, Eraso LH, Xie D, Sha D, Mohler ER 3rd. Mean platelet volume and prevalence of peripheral artery disease, the National Health and Nutrition Examination Survey, 1999-2004. Atherosclerosis 2010;213:586-91. doi: 10.1016/j. atherosclerosis.2010.09.010
  12. Vizioli L, Muscari S, Muscari A. The relationship of mean platelet volume with the risk and prognosis of cardiovascular diseases. Int J Clin Pract 2009;63:1509-15. doi: 10.1111/j.1742- 1241.2009.02070.x
  13. Kaplan KL, Owen J. Plasma levels of beta-thromboglobulin and platelet factor 4 as indices of platelet activation in vivo. Blood 1981;57:199-202
  14. Martin JF, Shaw T, Heggie J, Penington DG. Measurement of the density of human platelets and its relationship to volume. Br J Haematol 1983;54:337-52
  15. Guthikonda S, Alviar CL, Vaduganathan M, Arikan M, Tellez A, DeLao T, et al. Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antipl