Journals / Türk Geriatri Dergisi / 2008 / Cilt: 11 - Sayı: 2

Kronik myeloid lösemili bir hastada gelişen osteomyelitis: Vaka raporu ve literatür değerlendirmesi

Chronic myelogenous leukemia presenting with osteomyelitis: A case report and revıew of literature

Pages
88–93
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To avoid secondary infections and complications, it is imperative that elderly patients have regular examinations and not wait for problems to occur.

📌 3 Key Takeaways

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Objective & Hypothesis:Chronic myelogenous leukemia (CML), osteomyelitis, and chronic periodontal diseases affect elderly people in common.
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Key Findings & Data:CML is a pluripotential stem cell disease and usually presents as an increased incidence of infections, generalized gingival hypertrophy, and gingival bleeding.
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Conclusion & Impact:To avoid secondary infections and complications, it is imperative that elderly patients have regular examinations and not wait for problems to occur.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Chronic myelogenous leukemia (CML), osteomyelitis, and chronic periodontal diseases affect elderly people in common. These disorders also have direct/indirect associations between them. CML is a pluripotential stem cell disease and usually presents as an increased incidence of infections, generalized gingival hypertrophy, and gingival bleeding. These may be the initial presenting features of the disease. Osteomyelitis is an inflammation of the bone and bone marrow in which reduced vascularity and osteocyte destruction occur. The clinical presentation and course depend on the virulence of the micro-organism involved and the patient's resistance. The reason that osteomyelitis varies in elderly is chronically impaired immune host response. We report an 83-year-old man with severe gingival bleeding who was referred to periodontology clinic for consultation. He had uncontrolled gingival bleeding from buccal side of lower right second molar. We extracted involved tooth and removed granulation tissues from cavity. Healing was satisfactory. Our preliminary diagnosis of osteomyelitis was confirmed by CT, and on pathological examination, he was also diagnosed as having CML. Treatment procedures must be individually designed, especially for elderly patients. To avoid secondary infections and complications, it is imperative that elderly patients have regular examinations and not wait for problems to occur.

Özet

Kronik myeloid lösemi (KML), osteomyelit ve kronik periodontal hastalıklar, ileri yaştaki bireyleri daha fazla etkilemektedir. Bu hastalıkların, birbirlerini üzerine de olumsuz yönde, dolaylı ve dolaysız etkileri vardır. KML, bir kök hücre hastalığıdır ve genellikle enfeksiyon sıklığında artış, generalize dişeti büyümesi ve dişeti kanaması ile seyretmektedir. Bu bulgular hastalığın erken dönem belirtileri olabilir. Kemik ve kemik iliğinin inflamasyonu olan osteomyelitis, vasküleritede azalmaya ve osteosit yıkımına neden olmaktadır. Hastalığın klinik görüntüsü ve ilerlemesi, etken mikroorganizmaya ve hastanın bu mikroorganizmaya karşı direncine bağlıdır. Yaşlı hastalarda osteomyelitisin farklı formlarının görülmesinin nedeni, sürekli olarak bozuk olan konak savunma sistemidir. Bu olgu sunumunda, şiddetli dişeti kanaması nedeni ile kliniğimize konsültasyon amacıyla yönlendirilen 83 yaşındaki erkek anlatılmaktadır. Yapılan muayenede, hastanın sağ alt ikinci molar dişinin, bukkal yüzeyinde kontrol edilemeyen dişeti kanaması mevcuttu. Söz konusu diş çekilerek, enfekte bölge kürete edildi. Klinik bulgular ışığında konulan osteomyelit teşhisi, BT ve patolojik değerlendirmelerle doğrulanırken, aynı örneklerde yapılan laboratuvar tetkiklerle hastaya KML teşhisi konuldu. Yaşlı bireylerde, tedavi prosedürleri, ikincil enfeksiyonları ve komplikasyonları en aza indirmek amacıyla bireysel olarak oluşturulmalıdır. Hastalar, herhangi bir şikayetlerinin tedavisi için hastanelere başvurduklarında, hekimleri tarafından uzman diş hekimlerine yönlendirilmeli ve kümülatif olarak ortaya çıkabilecek dental ve periodontal sorunları erken teşhis ve müdahale ile önlenmelidir.

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Cite This Article

GÜZELDEMİR, E., TOYGAR, U. H., BAL, N., BOGA, C. (2022). Kronik myeloid lösemili bir hastada gelişen osteomyelitis: Vaka raporu ve literatür değerlendirmesi. Türk Geriatri Dergisi, Cilt: 11 - Sayı: 2, 88–93. https://ajindex.com/articles/624212

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