Journals / Türk Geriatri Dergisi / 2010 / Cilt: 13 - Sayı: 1

Urinary incontinence in the elderly and its pharmacological treatment

Yaşlılarda üriner inkontinans ve farmakolojik tedavisi

Pages
59–66
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Each has demonstrated efficacy for the treatment however, their pharmacokinetic and adverse event profiles differ somewhat due to structural differences, muscarinic receptor subtype selectivities, and organ selectivities.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Urinary incontinence, which may lead serious psychological and social complications such as depression, anxiety, embarrassment, and social isolation is an important and common health care problem affecting the elderly population.
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Key Findings & Data:Successful management of urinary incontinence in this population requires an understanding of the anatomical and physiological changes due to the aging process.
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Conclusion & Impact:Each has demonstrated efficacy for the treatment however, their pharmacokinetic and adverse event profiles differ somewhat due to structural differences, muscarinic receptor subtype selectivities, and organ selectivities.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Urinary incontinence, which may lead serious psychological and social complications such as depression, anxiety, embarrassment, and social isolation is an important and common health care problem affecting the elderly population. Successful management of urinary incontinence in this population requires an understanding of the anatomical and physiological changes due to the aging process. Different therapeutic modalities often lead to an appreciable improvement of the symptoms, and sometimes a cure even in old patients. Pharmacologic therapy may be an option, however when selecting a drug therapy for the management of an elderly patient, in addition to considering evidence of clinical efficacy and tolerability, issues of safety specific to this age group should be borne in mind. Anticholinergic agents are important in the treatment of urinary incontinence. Each has demonstrated efficacy for the treatment however, their pharmacokinetic and adverse event profiles differ somewhat due to structural differences, muscarinic receptor subtype selectivities, and organ selectivities.

Özet

Üriner inkontinans yaşlı popülasyonu etkileyen, depresyon, anksiyete, utanma ve sosyal izolasyon gibi ciddi psikolojik ve sosyal komplikasyonlara neden olabilecek önemli ve yaygın bir sağlık problemidir. Bu popülasyonda üriner inkontinansın başarılı bir şekilde tedavi etmek için yaşa bağlı gelişen anatomik ve fizyolojik değişiklikleri bilmek şarttır. Değişik tedavi modaliteleri ile kabul edilebilir iyileşme hatta tamamen kuruluk elde edilebilmektedir. Farmakolojik tedavi bir tedavi seçeneği olmakla beraber yaşlı hastalarda ilaç tedavisini seçerken klinik etkinlik ve tolere edilebilirliğin yanı sıra bu yaş grubuna özel güvenilirlik de göz önünde bulundurulmalıdır. Antikolinerjikler üriner inkontinansın tedavisinde kullanılan önemli ilaçlardandır. Antikolinerjikler tedavide etkin ajanlardır ancak her birinin yapısal değişiklikler, muskarinik reseptör alt tip selektiviteleri ve organ selektivitelerinden kaynaklanan farklı farmakokinetik ve yan etki profili vardır.

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Cite This Article

İNCİ, K., ERGEN, A. (2022). Urinary incontinence in the elderly and its pharmacological treatment. Türk Geriatri Dergisi, Cilt: 13 - Sayı: 1, 59–66. https://ajindex.com/articles/624141

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References (15)

  1. Abrams P, Cardozo L, Fall M, et al. The standardisation of terminology in lower urinary tract function: Report from the standardisation sub-committee of the international continence society. Urology 2003
  2. 49 2. Diokno AC, Estanol MV, Mallett V. Epidemiology of lower urinary tract dysfunction. Clin Obstet Gynecol 2004
  3. Gray ML. Gender, race, and culture in research on ui: Sensitivity and screening are integral to adequate patient care. Am J Nurs 2003 (Suppl)
  4. Vandoninck V, Bemelmans BL, Mazzetta C, et al. The prevalence of urinary incontinence in community-dwelling married women: A matter of definition. BJU Int 2004
  5. Thomas TM, Plymat KR, Blannin J, Meade TW. Prevalence of urinary incontinence. Br Med J 1980
  6. Malmsten UG, Milsom I, Molander U, Norlen LJ. Urinary incontinence and lower urinary tract symptoms: An epidemiological study of men aged 45 to 99 years. J Urol 1997
  7. Adedokun AO, Wilson MM. Urinary incontinence: Historical, global, and epidemiologic perspectives. Clin Geriatr Med 2004
  8. Adelmann PK. Prevalence and detection of urinary incontinence among older medicaid recipients. J Health Care Poor Underserved 2004
  9. Ar›kan E, Özcan E, Bardak A, Ketenci A. Huzurevinde yaflayan bir grup kad›nda üriner enkontinans. Turkish Journal of Geriatrics 2002
  10. Aslan E, Beji NK, Erkan HA, Yalcin O, Gungor F. Urinary incontinence (ui) and quality of life (qol) of the elderly residing in residential homes in turkey. Arch Gerontol Geriatr 2009
  11. Sykes D, Castro R, Pons ME, et al. Characteristics of female outpatients with urinary incontinence participating in a 6-month observational study in 14 european countries. Maturitas 2005
  12. 52 (Suppl 2):S13-23. 12. Perry S, Shaw C, Assassa P, et al. An epidemiological study to establish the prevalence of urinary symptoms and felt need in the community: The leicestershire mrc incontinence study. Leicestershire mrc incontinence study team. J Public Health Med 2000
  13. Stoddart H, Donovan J, Whitley E, Sharp D, Harvey I. Urinary incontinence in older people in the community: A neglected problem? Br J Gen Pract 2001
  14. Stothers L, Thom D, Calhoun E. Urologic diseases in america project: Urinary incontinence in males—demographics and economic burden. J Urol 2005
  15. Gavira Iglesias FJ, Caridad Y, Ocerin JM, et al. Prevalence and psychosocial impact of urinary incontinen