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Journals / Türk Geriatri Dergisi / 2013 / Cilt: 16 - Sayı: 3

Postmenopozal meme kanserli hastalarda geriatrik ve geriatrik olmayan hasta gurupları: lenfovasküler invazyon önemli olarak farklıdır

Gerıatrıc versus non-gerıatrıc groups ın postmenopausal breast cancer patıents: lymphovascular ınvasıon ıs sıgnıfıcantly dıfferent

Abdullah BÜYÜKÇELİK
Yasemin CİHAN BENDERLİ
Abdülsamet ERDEN
Tuncay ASLAN
Zeki AKÇA
Hasan MUTLU
Pages
305–308
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The two groups were compared with regard to age, stage, histology, hormone receptor status, grade, lymphovascular invasion and disease free and overall survival.Results: The lymphovascular invasion rate was much higher in non-geriatric patients compared to geriatric patients (p=0.008).

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Women 65 years of age or older make up one half of all new breast cancer patients.
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Key Findings & Data:In this retrospective analysis we evaluated whether geriatric postmenopausal breast cancer patients are different from non-geriatric patients, regarding prognostic factors and survival rates.Materials and Method: A total of 291 patients with postmenopausal breast cancer were included.
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Conclusion & Impact:The two groups were compared with regard to age, stage, histology, hormone receptor status, grade, lymphovascular invasion and disease free and overall survival.Results: The lymphovascular invasion rate was much higher in non-geriatric patients compared to geriatric patients (p=0.008).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Women 65 years of age or older make up one half of all new breast cancer patients. These patients are called geriatric patients. Their prognosis is better than the younger patients. Generally, they are offered less intensive treatment. In this retrospective analysis we evaluated whether geriatric postmenopausal breast cancer patients are different from non-geriatric patients, regarding prognostic factors and survival rates.Materials and Method: A total of 291 patients with postmenopausal breast cancer were included. Of these, 108 patients were in the geriatric group while 183 were in the non-geriatric group. The two groups were compared with regard to age, stage, histology, hormone receptor status, grade, lymphovascular invasion and disease free and overall survival.Results: The lymphovascular invasion rate was much higher in non-geriatric patients compared to geriatric patients (p=0.008). Disease free survival and overall survival were similar.Conclusion: Geriatric patients have more favorable prognostic factors than non-geriatric patients with postmenopausal breast cancer.

Özet

Giriş: Yeni meme kanserli kadınların yarısı 65 yaş ve üzeridir. Geriatrik hasta gurubu olarak adlandırılan (65 yaş ve üzeri) bu gurubun prognozu daha genç hastalara göre daha iyidir. Genel olarak daha az toksik kemoterapi rejimleri önerilmektedir. Bu çalışmada postmenopozal meme kanserli hastalarda geriatrik hasta gurubu ile geriatrik olmayan hasta gurubu prognostik faktörler ve sağkalım açısından karşılaştırılması amaçlanmıştır.Gereç ve Yöntem: Toplam 291 postmenopozal meme kanserli hastanın hastane kayıtları geriye dönük olarak incelendi. 108 hasta geriatrik, 183 hasta geriatrik olmayan gurupta idi. Yaş, evre, histoloji, reseptör durumu, tümör greydi, lenfovasküler invazyon, hastalıksız ve genel sağkalım açısından guruplar karşılaştırıldı.Bulgular: Prognostik faktörler açısından bakıldığında lenfovasküler invazyon oranı geriatrik olmayan hasta grubunda daha fazla idi (p=0.008). Sağkalım süreleri her iki gurupta benzerdi.Sonuç: Geriatrik meme kanserli hastaların postmenopozal meme kanserli hastalardan daha iyi prognostik faktörlere sahip olduğu düşünülebilir.

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Cite This Article

BÜYÜKÇELİK, A., BENDERLİ, Y. C., ERDEN, A., ASLAN, T., AKÇA, Z., MUTLU, H. (2022). Postmenopozal meme kanserli hastalarda geriatrik ve geriatrik olmayan hasta gurupları: lenfovasküler invazyon önemli olarak farklıdır. Türk Geriatri Dergisi, Cilt: 16 - Sayı: 3, 305–308. https://ajindex.com/articles/623930

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