Journals / Türk Geriatri Dergisi / 2015 / Cilt: 18 - Sayı: 1

GERİATRİK HEMODİYALİZ HASTALARINDA MALNÜTRİSYON İNFLAMASYON SKORU, ANTROPOMETRİK BELİRTEÇLER VE ERİTROPOİETİN İHTİYACI

MALNUTRITION-INFLAMMATION SCORE, ANTHROPOMETRIC INDICES, AND ERYTHROPOIETIN REQUIREMENT IN GERIATRIC HEMODIALYSIS PATIENTS

Pages
3–9
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Malnutrition-inflammation score was determined incorrelation with weekly erythropoietin dose per weight in both geriatric and adult patient groups (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Studies have demonstrated that there is a correlation between malnutrition,inflammation, and erythropoietin requirement in adult hemodialysis patients.
📊
Key Findings & Data:Results: Mean age of 154 patients included in the study was 59.5±14.5 years; 81 were male and 68 were geriatric (age >=65 years).
💡
Conclusion & Impact:Malnutrition-inflammation score was determined incorrelation with weekly erythropoietin dose per weight in both geriatric and adult patient groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Studies have demonstrated that there is a correlation between malnutrition,inflammation, and erythropoietin requirement in adult hemodialysis patients. However, in geriatric hemodialysis patients, no evident data has been found associated with this relationship. Thepurpose of this study is to investigate the relation between malnutrition-inflammation score, erythropoietin requirement, and erythropoietin resistance in geriatric hemodialysis patients. Materials and Method: One hundred fifty-four adult hemodialysis patients were includedin this cross-sectional study. Erythropoietin resistance index, weekly erythropoietin dose, weeklyerythropoietin dose per weight, and malnutrition-inflammation score were calculated for all patients. Measurements of laboratory and anthropometric parameters associated with nutritionand inflammation were performed. Results: Mean age of 154 patients included in the study was 59.5±14.5 years; 81 were male and 68 were geriatric (age >=65 years). The median duration of dialysis was 36 months (interquartile range, 18-76). Mean malnutrition-inflammation score was found to be higher in geriatric patients than in adult patients (p=0.004). Malnutrition-inflammation score was determined incorrelation with weekly erythropoietin dose per weight in both geriatric and adult patient groups (p

Özet

Giriş: Çalışmalarda erişkin hemodiyaliz hastalarında malnütrisyon ve inflamasyon ile eritropoietin ihtiyacı arasında korelasyon olduğu gösterilmiştir. Fakat geriatrik hemodiyaliz hastalarındabu ilişki ile ilgili belirgin veriler bulunmamaktadır. Bu çalışmanın amacı geriatrik hemodiyaliz hastalarında malnutrisyon inflamasyon skoru, eritropoietin ihtiyacı ve eritropoietin direnci ilişkisininaraştırılmasıdır.Gereç ve Yöntem: Bu kesitsel çalışmaya yüz elli dört erişkin hemodiyaliz hastası alındı. Hastaların eritropoietin direnç indeksi, haftalık eritropoietin dozu, haftalık kilo başına eritropoietin dozu ve malnutrisyon inflamasyon skoru hesaplandı. Hastaların nütrisyon ve inflamasyon ilişkili laboratuar ve antropometrik parametreleri ölçüldü. Bulgular: Çalışmaya alınan 154 hastanın yaş ortalaması 59,5±14,5 yıl, 81'i erkek, 68'i geriatrik (yaş >=65 yıl) idi. Ortalama diyaliz süresi 36 aydı . Geriatrik hastalarda, malnutrisyon inflamasyon skoru ortalaması daha yüksek bulundu (p=0,004). Malnutrisyon inflamasyon skoru, geriatrik ve erişkin hasta gruplarının her ikisinde de haftalık kilo başına eritropoietin dozu ile korele bulundu (sırasıyla p

🔖

Cite This Article

NALBANT, A., KARACAER, C., SİPAHİ, S., CİNEMRE, H., TAMER, A., VARIM, C., KAYA, T. (2022). GERİATRİK HEMODİYALİZ HASTALARINDA MALNÜTRİSYON İNFLAMASYON SKORU, ANTROPOMETRİK BELİRTEÇLER VE ERİTROPOİETİN İHTİYACI. Türk Geriatri Dergisi, Cilt: 18 - Sayı: 1, 3–9. https://ajindex.com/articles/623852

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. Canaud B, Tong L, Tentori F, et al. Clinical practices and out- comes in elderly hemodialysis patients: results from the dialysis outcomes and practice patterns study (DOPPS). Clin J Am Soc Nephrol 2011;6(7):1651-62. (PMID:21734085). Kidney Disease: Improving Global Outcomes (KDIGO) Ane- mia Work Group. KDIGO Clinical Practice Guideline for Ane- mia in Chronic Kidney Disease. Kidney Int Suppl 2012;2(4):279-335. (PMID:25018943). Kanbay M, Perazella MA, Kasapoglu B, Koroglu M, Covic A. Erythropoiesis stimulatory agent- resistant anemia in dialysis patients: review of causes and management. Blood Purif 2010;29(1):1-12. (PMID:19816014). Demir M, Kucuk A, Sezer MT, Altuntas A, Kaya S. Malnutri- tion-inflammation score and endothelial dysfunction in hemo- dialysis patients. J Ren Nutr 2010;20(6):377-83. (PMID:20663689). Rambod M, Bross R, Zitterkoph J, et al. Association of malnut- rition-inflammation score with quality of life and mortality in hemodialysis patients: a 5-year prospective cohort study. Am J Kidney Dis 2009;53(2):298-309. (PMID:19070949). Akgul A, Bilgic A, Sezer S, et al: Effect of protein-energy mal- nutrition on erythropoietin requirement in maintenance hemo- dialysis patients. Hemodial Int 2007;11(2):198-203. (PMID:17403171). Kalantar-Zadeh K, McAllister CJ, Lehn RS, Lee GH, Nissenson AR, Kopple JD. Effect of malnutrition-inflammation complex syndrome on EPO hyporesponsiviness in maintenance hemodi- alysis patients. Am J Kidney Dis 2003;42(4):761-73. (PMID:14520627). Pang WW, Schrier SL. Anemia in the elderly. Curr Opin He- matol 2012;19(3):133-40. (PMID:22495692). Barnett AL, Cremieux PY. Dose conversion from epoetin alfa to darbepoetin alfa for patients with chronic kidney disease recei- ving hemodialysis. Pharmacotherapy 2003;23(5):690-4. (PMID:12741447). National Kidney Foundation-Kidney Disease Outcome Quality Initiative Committee. Adult guidelines. American Journal of Kidney Diseases Suppl 2000;35(6):s17-104. [Internet] Ava- ilable from: http://www.ajkd.org/article/S0272-6386(00) 44537-3/pdf. Accessed:25.08.2014.
  2. Kilpatrick RD, Critchlow CW, Fishbane S, et al. Greater epoe- tin alfa responsiveness is associated with improved survival in hemodialysis patients. Clin J Am Soc Nephrol 2008;3(4):1077- 83. (PMID:18417744). Priyadarshi A, Shapiro JI. Erythropoietin resistance in the tre- atment of the anemia of chronic renal failure. Semin Dial 2006;19(4):273-8. (PMID:16893403). Kalantar-Zadeh K, Abbott KC, Salahudeen AK, Kilpatrick RD, Horwich