Journals / Türk Geriatri Dergisi / 2017 / Cilt: 20 - Sayı: 3

KRONİK DİRENÇLİ DERMATOZ: ASİTRETİN VE TOPİKAL TAKROLİMUS İLE TEDAVİ EDİLMİŞ SKALPİN EROZİV PÜSTÜLER DERMATOZU

CHRONIC RECALCITRANT DERMATOSIS: EROSIVE PUSTULAR DERMATOSIS OF THE SCALP TREATED WITH ACITRETIN AND TOPICAL TACROLIMUS

Pages
249–253
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The use of oral acitretin 50 mg/day and tacrolimus ointment led to a complete and permanent remission

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Erosive pustular dermatosis of the scalp is an uncommon disorder of the scalp, which causes chronic sterile pustules and non-healing erosions, leading to cicatricial alopecia and skin cancer.
📊
Key Findings & Data:In this report, we describe the case of a 78-year-old male patient having chronic recalcitrant ulceration on the scalp for 4 years, which was misdiagnosed and inappropriately treated with various topical agents.
💡
Conclusion & Impact:The use of oral acitretin 50 mg/day and tacrolimus ointment led to a complete and permanent remission
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Erosive pustular dermatosis of the scalp is an uncommon disorder of the scalp, which causes chronic sterile pustules and non-healing erosions, leading to cicatricial alopecia and skin cancer. The disease usually affects older individuals. The exact pathogenesis of erosive pustular dermatosis of the scalp is unknown but microscopic examination reveals inflammation with neutrophils. As a result of limited efficacy of various medical and surgical modalities, erosive pustular dermatosis of the scalp patients present a therapeutic challenge. In this report, we describe the case of a 78-year-old male patient having chronic recalcitrant ulceration on the scalp for 4 years, which was misdiagnosed and inappropriately treated with various topical agents. The use of oral acitretin 50 mg/day and tacrolimus ointment led to a complete and permanent remission

Özet

Skalpin Eroziv Püstüler Dermatozu, skatrisyel alopesi ve deri kanseri ile sonuçlanabilen kronik steril püstüllere ve iyileşmeyen erozyonlara neden olan skalpte yerleşim gösteren nadir bir hastalıktır. Hastalık genellikle yaşlı kişileri etkilemektedir. Skalpin Eroziv Püstüler Dermatozu hastalığının esas patogenezi bilinmemektedir ancak mikroskopik muayenede nötrofilik inflamasyon izlenir. Çeşitli medikal ve cerahi tedavilerin sınırlı etkinlik göstermeleri sebebi ile, Skalpin Eroziv Püstüler Dermatozu hastalarının tedavilerinde güçlük yaşanabilmektedir. Bu çalışmada dört yıldan beri mevcut olan skalp yerleşimli, yanlış tanı almış ve çeşitli topikal ajanlarla uygun olmayan şekillerde tedavi edilmiş kronik dirençli ülserasyonu olan 78 yaşında bir erkek hastayı sunmaktayız. Oral asitretin (50 mg/gün) ve takrolimus pomad kullanımı tam ve devamlı remisyonu sağlamıştır

🔖

Cite This Article

YALÇIN, B., BOZDOĞAN, Ö., ÜNAL, D. T., İNCEL, P. U. (2022). KRONİK DİRENÇLİ DERMATOZ: ASİTRETİN VE TOPİKAL TAKROLİMUS İLE TEDAVİ EDİLMİŞ SKALPİN EROZİV PÜSTÜLER DERMATOZU. Türk Geriatri Dergisi, Cilt: 20 - Sayı: 3, 249–253. https://ajindex.com/articles/623732

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Kim KR, Lee JY, Kim MK, Yoon TY. Erosive pustular dermatosis of the scalp following herpes zoster: successful treatment with topical tacrolimus. Ann Dermatol 2010;22(2):232-4. (PMID:20548924)
  2. Tavares-Bello R. Erosive pustular dermatosis of the scalp. A chronic recalcitrant dermatosis developed upon CO2 laser treatment. Dermatology 2009;219(1):71-2. (PMID:26243684)
  3. Guarneri C, Vaccaro M. Erosive pustular dermatosis of the scalp following topical methylaminolaevulinate photodynamic therapy. J Am Acad Dermatol 2009;60(3):521-2. Epub 2009/02/24. (PMID:19231656)
  4. Pernet C, Bessis D, Dereure O, Raison-Peyron N. Erosive pustular dermatosis of the scalp developing after a burn from a hair-bleaching procedure. Clin Exp Dermatol 2017;42(2):233-4. (PMID:27862169)
  5. Watanabe S, Takizawa K, Hashimoto N, Ishibashi Y. Pustular dermatosis of the scalp associated with autoimmune diseases. J Dermatol 1989;16(5):383-7. (PMID:2574730)
  6. Darwich E, Munoz-Santos C, Mascaro JM, Jr. Erosive pustular dermatosis of the scalp responding to acitretin. Arch Dermatol 2011;147(2):252-3. (PMID:19094119)
  7. Ikeda M, Arata J, Isaka H. Erosive pustular dermatosis of the scalp successfully treated with oral zinc sulphate. Br J Dermatol 1982;106(6):742-3. (PMID:20548924)
  8. Di Lernia V, Ricci C. Familial erosive pustular dermatosis of the scalp and legs successfully treated with ciclosporin. Clin Exp Dermatol 2016;41(3):334-5. (PMID:16205074)
  9. Broussard KC, Berger TG, Rosenblum M, Murase JE. Erosive pustular dermatosis of the scalp: a review with a focus on dapsone therapy. J Am Acad Dermatol 2012;66(4):680-6. (PMID:24173187)
  10. Marzano AV, Ghislanzoni M, Zaghis A, Spinelli D, Crosti C. Localized erosive pustular dermatosis of the scalp at the site of a cochlear implant: successful treatment with topical tacrolimus. Clin Exp Dermatol 2009;34(5):e157-9. (PMID:19094119)
  11. Tardio NB, Daly TJ. Erosive pustular dermatosis and associated alopecia successfully treated with topical tacrolimus. J Am Acad Dermatol 2011;65(3):e93-4. (PMID:21839311)
  12. Zahdi MR, Seidel GB, Soares VC, Freitas CF, Mulinari-Brenner FA. Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus. An Bras Dermatol 2013;88(5):796- 8. (PMID:18480944)
  13. Petersen BO, Bygum A. Erosive pustular dermatosis of the scalp: a case treated successfully with isotretinoin. Acta Derm Venereol 2008;88(3):300-1. (PMID:16205074)
  14. Mastroianni A, Cota C, Ardigo M,