Journals / Türk Geriatri Dergisi / 2018 / Cilt: 21 - Sayı: 4

ASSOCIATION BETWEEN VITAMIN D LEVEL AND TOTAL COMORBIDITY STATUS IN GERIATRIC PATIENTS

GERİATRİ YAŞ GRUBUNDAKİ HASTALARDA D VİTAMİNİ DÜZEYİ İLE TOTAL KOMORBİDİTE DURUMU ARASINDAKİ İLİŞKİ

Pages
536–543
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

This result suggests that vitamin D deficiency may be a risk factor for comorbiditiesin geriatric patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Vitamin D is known as an anti-inflammatory, antitumor, and immunemodulating hormone, which plays an important role in common diseases in the geriatricpopulation, such as hypertension and cerebrovascular disorders.
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Key Findings & Data:Geriatric patients (aged≥65 years) who underwent serum 25(OH)D evaluation to determine the vitamin D statusduring the last 3 months were assessed for eligibility.
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Conclusion & Impact:This result suggests that vitamin D deficiency may be a risk factor for comorbiditiesin geriatric patients.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Vitamin D is known as an anti-inflammatory, antitumor, and immunemodulating hormone, which plays an important role in common diseases in the geriatricpopulation, such as hypertension and cerebrovascular disorders. Vitamin D deficiency has beenlinked to various diseases in the literature. However, the association between vitamin D andmultiple comorbidities remains unclear due to limited published data. The aim of the presentstudy was to evaluate the association between vitamin D levels and multiple comorbidities inelderly patients.Materials and Method: The study design was cross-sectional. Geriatric patients (aged≥65 years) who underwent serum 25(OH)D evaluation to determine the vitamin D statusduring the last 3 months were assessed for eligibility. Demographic data and 25(OH)D levelsof patients were obtained from the electronic database of the hospital and a telephonicinterview. In addition, a comorbidity questionnaire was completed via telephonic interviews.The correlation between comorbidity scores, demographic data, and vitamin D levels in elderlypatients was analyzed.Results: Data on 25(OH)D levels in 685 geriatric patients was obtained. Among thesepatients, 211 (169 female, 42 male) who were contacted over telephone were enrolled. Themean values for age, vitamin D level, and comorbidity scores were 70.4±5.0 years, 16.8±9.2ng/ml, and 11.3±4.7, respectively. A moderate-good negative correlation was found between25(OH)D levels and comorbidity scores (r=−0.503).Conclusion: Low vitamin D levels were associated with total comorbidity status in geriatricpatients. This result suggests that vitamin D deficiency may be a risk factor for comorbiditiesin geriatric patients.

Özet

Giriş: Vitamin D, anti-inflamatuvar, anti-tümör ve immünmodulatuvar etkileri nedeniyle; hipertansiyon ve serebrovasküler hastalıklar gibi, geriatrik popülasyonda sık görülen bazı sağlık problemlerinde önemli role sahiptir. Literatürde farklı hastalıklarda vitamin D eksikliğinin rolü gösterilmiştir. Ancak, birden fazla sağlık probleminin olduğu ileri yaş grubunda, vitamin D seviyesi ile komorbidite arasındaki ilişki net değildir. Bu çalışmada, yaşlı hastalarda, vitamin D seviyesi ile komorbidite arasındaki ilişkinin saptanması amaçlanmıştır. Gereç ve Yöntem: Çalışma dizaynı kesitseldir. Son 3 ay içinde 25(OH)D seviyeleri bakılmış olan geriatrik hastalar (≥65 yaş) uygunluk açısından değerlendirildi. Hastane veri tabanından ve telefon görüşmesi ile, hastaların demografik verileri ve 25(OH)D seviyeleri kaydedildi. Ayrıca, telefon görüşmesi ile hastaların komorbidite anketi dolduruldu. Geriatrik hastaların, komorbidite skoru, demografik özellikleri ve serum 25(OH)D düzeyi arasındaki korelasyon değerlendirildi. Bulgular: Veri tabanında 65 yaş ve üzeri toplam 685 hastanın 25(OH)D seviyeleri mevcuttu. Bu hastalardan telefon aracılığıyla ulaşılabilen 211 hasta (169 kadın, 42 erkek) çalışmaya dahil edildi. Hastaların yaş, 25(OH)D düzeyi ve komorbidite skoru için ortalama değerleri sırasıyla; 70.4±5.0 yıl, 16.8±9.2 ng/ml ve 11.3±4.7 idi. Yapılan korelasyon analizinde, serum 25(OH) D seviyesinin, komorbidite skoru ile orta-iyi derecede negatif korele olduğu tespit edildi (r=−0.503). Sonuç: Geriatrik hastalarda düşük vitamin D düzeyleri total komorbidite durumu ile ilişkili bulunmuştur. Bu nedenle, vitamin D eksikliği yaşlı hastalarda komorbidite için bir risk faktörü olarak düşünülebilir.

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Cite This Article

BAŞARAN, S., GÖKÇEN, N., BENLİDAYI, İ. C., KOCAER, A. (2022). ASSOCIATION BETWEEN VITAMIN D LEVEL AND TOTAL COMORBIDITY STATUS IN GERIATRIC PATIENTS. Türk Geriatri Dergisi, Cilt: 21 - Sayı: 4, 536–543. https://ajindex.com/articles/623716

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