Journals / Türk Geriatri Dergisi / 2018 / Cilt: 21 - Sayı: 3

EARLY BLOOD TRANSFUSION MAY PREVENT POSTOPERATIVE COGNITIVE DYSFUNCTION AFTER HIP ARTHROPLASTY IN ELDERLY PATIENTS

KALÇA ARTROPLASTİSİ GEÇİREN YAŞLI HASTALARDA ERKEN KAN REPLASMANI AMELİYAT SONRASI BİLİŞSEL DİSFONKSİYONU ÖNLEYEBİLİR

Pages
402–409
Publication Date
2022-11-03
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The duration of cognitivedysfunction was significantly lower in the second group (10.8±1.2 vs. 8.9±1.5 days; p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The number of joint arthroplasties in the elderly continues to increasewith the increase in elderly population.
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Key Findings & Data:We aimedto determine whether blood loss during or after surgery and the approach for the replacementof this loss affected postoperative cognitive dysfunction frequency and duration.Materials and Method: A prospective study of elderly (>75 years) patients who underwenttotal/partial hip arthroplasty due to femoral neck or intertrochanteric fractures was conducted.Patients were randomised into two groups.
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Conclusion & Impact:The duration of cognitivedysfunction was significantly lower in the second group (10.8±1.2 vs. 8.9±1.5 days; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: The number of joint arthroplasties in the elderly continues to increasewith the increase in elderly population. Postoperative cognitive dysfunction is an importantcomplication after surgery in elderly patients. However, the exact cause of postoperativecognitive dysfunction and factors contributing to its development remain unknown. We aimedto determine whether blood loss during or after surgery and the approach for the replacementof this loss affected postoperative cognitive dysfunction frequency and duration.Materials and Method: A prospective study of elderly (>75 years) patients who underwenttotal/partial hip arthroplasty due to femoral neck or intertrochanteric fractures was conducted.Patients were randomised into two groups. The first group underwent transfusion whenhaemoglobin values reduced below 9.0 mg/dL, whereas the second group underwent earlierblood transfusion according to the volume of blood loss during and after surgery. All groupswere similar in terms of factors considered to be associated with postoperative cognitivedysfunction. An experienced neurologist assessed patients’ cognitive functions using theStandardized Mini-Mental Status Examination test and clinical examinations pre- andpostoperatively.Results: In total, 48 patients in the first group and 13 in the second group (early interventiongroup) were diagnosed with postoperative cognitive dysfunction. The duration of cognitivedysfunction was significantly lower in the second group (10.8±1.2 vs. 8.9±1.5 days; p

Özet

Giriş: Yaşlanan insanlardaki eklem artroplastilerinin sayısı yaşlı nüfus artışı ile birlikte artmaya devam etmektedir. Postoperatif bilişsel disfonksiyon, yaşlı hastalarda cerrahiden sonra önemli bir komplikasyondur. Bununla birlikte, postoperatif bilişsel disfonksiyonun kesin nedeni ve gelişimine katkıda bulunan faktörler bilinmemektedir. Ameliyat sırasında veya sonrasında kan kaybının ve bu kaybın yerine konulma yaklaşımının postoperatif bilişsel disfonksiyon sıklığını ve süresini etkileyip etkilemediğini saptamak amaçlandı. Gereç ve Yöntem: Femur boynu veya intertrokanterik kırıklara bağlı total/parsiyel kalça artroplastisi yapılan yaşlı (>75 yaş) hastalar prospektif olarak incelendi. Hastalar randomize olarak iki gruba ayrıldı. Birinci gruba hemoglobin değerleri 9.0 mg / dL’nin altına düştüğünde transfüzyon yapıldı, ikinci gruba cerrahi sırasında ve sonrasında kan kaybı hacmine göre kan transfüzyonu yapıldı. Tüm gruplar, postoperatif bilişsel disfonksiyon ile ilişkili olduğu düşünülen faktörler açısından benzerdi. Deneyimli bir nörolog, hastaların bilişsel işlevlerini, Standardize Mini-Mental Test, klinik muayene kullanarak operasyon öncesi ve sonrası değerlendirildi. Bulgular: Birinci grupta 48 ve ikinci grupta (erken müdahale grubu) 13 hasta postoperatif bilişsel disfonksiyon tanısı aldı. Bilişsel disfonksiyon süresi ikinci grupta (10.8±1.2 vs. 8.9±1.5 gün; p

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Cite This Article

DAŞAR, U., MUTLU, T. (2022). EARLY BLOOD TRANSFUSION MAY PREVENT POSTOPERATIVE COGNITIVE DYSFUNCTION AFTER HIP ARTHROPLASTY IN ELDERLY PATIENTS. Türk Geriatri Dergisi, Cilt: 21 - Sayı: 3, 402–409. https://ajindex.com/articles/623682

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