Journals / Türk Geriatri Dergisi / 2018 / Cilt: 21 - Sayı: 3

ASSESSMENT OF P WAVE/QT INTERVAL DISPERSION, TP-E INTERVAL, TP-E/QT RATIO AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION IN GERIATRIC PATIENTS WITH AORTIC STENOSIS

AORT DARLIĞI OLAN GERİATRİK HASTALARDA TRANSKATETER AORT KAPAK İMPLANTASYONU SONRASI P DALGA/QT İNTERVAL DİSPERSİYONU, TP-E İNTERVAL VE TP-E/QT ORANININ DEĞERLENDİRİLMESİ

Pages
285–293
Publication Date
2022-11-05
DOI
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P wave/QT interval dispersion, Tp-e interval and Tp-e/QT ratio values before and 3rd months after implantation were calculated and compared.Results: There was a statistically significant decline in P wave/QT interval dispersion, Tp-e interval, Tp-e/QT ratio values between preoperative, and 3rd, months (43.72±7.78 vs. 35.15±8.92, 61.64±17.36 vs. 49.41±12.64, 84.59±7.64 vs. 73.21±6.46, 0.21±0.01 vs. 0.18±0.01, respectively, p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: One of the most important reasons for a high mortality and morbidity rate in geriatric patients with calcific aortic stenosis is arrhythmias.
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Key Findings & Data:Although hemodynamic and functional recoveries are established after transcatheter aortic valve implantation, whether it leads to a decrease in the risk of atrial fibrillation, ventricular arrhythmia and sudden cardiac death remains unclear.
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Conclusion & Impact:P wave/QT interval dispersion, Tp-e interval and Tp-e/QT ratio values before and 3rd months after implantation were calculated and compared.Results: There was a statistically significant decline in P wave/QT interval dispersion, Tp-e interval, Tp-e/QT ratio values between preoperative, and 3rd, months (43.72±7.78 vs. 35.15±8.92, 61.64±17.36 vs. 49.41±12.64, 84.59±7.64 vs. 73.21±6.46, 0.21±0.01 vs. 0.18±0.01, respectively, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: One of the most important reasons for a high mortality and morbidity rate in geriatric patients with calcific aortic stenosis is arrhythmias. Transcatheter aortic valve implantation is an alternative to conventional aortic valve surgery for high-risk patients because of its less-invasive nature. Although hemodynamic and functional recoveries are established after transcatheter aortic valve implantation, whether it leads to a decrease in the risk of atrial fibrillation, ventricular arrhythmia and sudden cardiac death remains unclear. Thus, this study aimed to evaluate the risks associated with aortic stenosis by assessing the rates of P wave dispersion for estimating the atrial fibrillation risk and QT interval dispersion, Tp-e interval, and Tp-e/QT ratio for ventricular arrhythmia and assessing sudden cardiac death risk before and after implantation.Materials and Method: In a retrospective study, a total of 39 subjects [14 males (35.89%) and 25 females (64.11%); mean age=81.51±8.79 years] were enrolled. P wave/QT interval dispersion, Tp-e interval and Tp-e/QT ratio values before and 3rd months after implantation were calculated and compared.Results: There was a statistically significant decline in P wave/QT interval dispersion, Tp-e interval, Tp-e/QT ratio values between preoperative, and 3rd, months (43.72±7.78 vs. 35.15±8.92, 61.64±17.36 vs. 49.41±12.64, 84.59±7.64 vs. 73.21±6.46, 0.21±0.01 vs. 0.18±0.01, respectively, p

Özet

Giriş:Kalsifik aort darlığı olan geriatrik hastalarda mortalite ve morbiditenin önemli birsebebi de aritmilerdir. Transkateter aort kapak implantasyonu daha az invaziv olması sebebiile yüksek riskli hastalarda konvansiyonel cerrahiye alternatifdir. Transkateter aort kapakimplantasyonu sonrası fonksiyonel ve hemodinamik düzelme olduğu iyi bilinmektedir, ancakimplantasyon sonrası atriyal fibrilasyon, ventriküler aritmi ve ani kardiyak ölüm riskinde azalma olup olmadığı net değildir. Bu çalışmanın amacı bu riskleri değerlendirmektir. Bu amaçla atriyal fibrilasyon riskini tahmin etmek için P dalga dispersiyonu, ventriküler aritmi ve ani kardiyakölüm riskini tahmin etmek için ise QT interval dispersiyonu, Tp-e interval ve Tp-e/QT oranıölçülerek transkateter aort kapak implantasyonu öncesi ve sonrası karşılaştırılmıştır. GereçveYöntem:Çalışmageriyedönükolarakyapıldı.Transkateteraortkapakimplantasyonu yapılan toplam 39 hasta çalışmaya dahil edilmiştir [14 erkek (%35.89) ve 25kadın (%64.11); ortalama yaş: 81.51±8.79 yıl]. P dalga dispersiyonu, QT interval dispersiyonu,Tp-e interval ve Tp-e/QT oranı transkateter aort kapak implantasyonu öncesi ve sonrası (3.ayda) hesaplanmış ve karşılaştırılmıştır. Bulgular: Transkateter aort kapak implantasyonu öncesi ve 3 ay sonrasında bakılan P dalga dispersiyonu, QT interval dispersiyonu, Tp-e interval ve Tp-e/QT oranı değerlerinde istatistiksel olarak anlamlı azalma olmuştur (43.72±7.78 vs. 35.15±8.92, 61.64±17.36 vs. 49.41±12.64,84.59±7.64 vs. 73.21±6.46, 0.21±0.01 vs. 0.18±0.01, sırasıyla, p

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Cite This Article

SEZGİN, A. T., DEMİRCAN, Ş., GÜLLÜ, H., BİLGEL, Z. G., MÜDERRİSOĞLU, H., YILMAZ, M. (2022). ASSESSMENT OF P WAVE/QT INTERVAL DISPERSION, TP-E INTERVAL, TP-E/QT RATIO AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION IN GERIATRIC PATIENTS WITH AORTIC STENOSIS. Türk Geriatri Dergisi, Cilt: 21 - Sayı: 3, 285–293. https://ajindex.com/articles/623665

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References (1)

  1. Carabello BA, Paulus WJ. Aortic stenosis. Lancet 2009;373(9667):956-66. (PMID:19232707) Sorgato A, Faggiano P, Aurigemma GP, Rusconi C, Gaasch WH. Ventricular arrhythmias in adult aortic stenosis: prevalence, mechanisms and clinical relevance. Chest 1998;113(2):482-91. (PMID:9498969). Chopard R, Teiger E, Meneveau N, et al. Baseline characteristics and prognostic implications of pre-existing and new-onset atrial fibrillation after transcatheter aortic valve implantation: results from the FRANCE-2 registry. JACC Cardiovasc Interv 2015;8(10):1346-55. (PMID:26315738). Kotting J, Schiller W, Beckmann A, et al. German Aortic Valve Score: a new scoring system for prediction of mortality related to aortic valve procedures in adults. Eur J Cardiothorac Surg 2013;43(5):971-7. (PMID:23477927). Zoghi M, Özyüncü N, Özal E, et al. Frequency of cardiovascular diseases and drug use in Turkish elderly population followed up at cardiology clinics: The ELDERTURK study. Turkish Journal of Geriatrics 2017;20(2):73-81. (in Turkish). Leon MB, Smith CR, Mack MJ, et al. Transcatheter aortic valve implantation for aortic stenosis in patients who can not undergo surgery. The New England Journal of Medicine 2010;363(17):1597-607. (PMID:20961243). Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aortic valve replacement in high-risk patients. The New England Journal of Medicine 2011;364(23):2187-98. (PMID:21639811). Pérez-Riera AR, de Abreu LC, Barbosa-Barros R, Grindler J, Fernandes-Cardoso A, Baranchuk A. P-wave dispersion: an update. Indian Pacing Electrophysiol J. 2016;16(4):126-33. (PMID:27924760). DE Maria E, Curnis A, Garyfallidis P, et al. QT dispersion on ECG Holter monitoring and risk of ventricular arrhythmias in patients with dilated cardiomyopathy. Heart Int 2006;2(1):33-8. (PMID:21977249). Smetana P, Schmidt A, Zabel M. Assessment of repolarization heterogeneity for prediction of mortality in cardiovascular disease: peak to the end of the T wave interval and non dipolar repolarization components. J Electrocardiol 2011;44(3):301-8. (PMID:21511064). Gupta P, Patel C, Patel H, et al. T(p-e)/QT ratio as an index of arrhythmogenesis. J Electrocardiol 2008;41(6):567-74. (PMID:18790499). Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 2015;28(1):1-39. (PMID: