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Journals / Türk Geriatri Dergisi / 2018 / Cilt: 21 - Sayı: 1

YAŞLI BEYİNDE ANESTEZİ VE CERRAHİNİN SONUÇLARI ÜZERİNE BİR KLİNİK İNCELEME: “AYIN KARANLIK YÜZÜ”

A CLINICAL REVIEW OF THE CONSEQUENCES OF ANESTHESIA AND SURGERY IN THE ELDERLY BRAIN: “THE DARK SIDE OF THE MOON”

Gözde İNAN
Zerrin ÖZKÖSE ŞATIRLAR
Pages
87–99
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It aims to emphasize the pathophysiological processes and risk factors of aging and potential anesthesia- and surgery-related neurodegeneration, since defining high-risk patients and preventing the problem can provide benefits for patients with neurodegenerative disease

📌 3 Key Takeaways

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Objective & Hypothesis:deterioration in the elderly may lead to serious medical and social consequences and is associated with increased morbidity, mortality, and high health care costs, the issue should be precisely addressed, and preventive strategies should be developed.
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Key Findings & Data:An emerging body of evidence suggests that anesthesia and surgery have an undesirable effect on long-term cognitive function in the elderly; however, there are no convincing human data to support this correlation.
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Conclusion & Impact:It aims to emphasize the pathophysiological processes and risk factors of aging and potential anesthesia- and surgery-related neurodegeneration, since defining high-risk patients and preventing the problem can provide benefits for patients with neurodegenerative disease
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

deterioration in the elderly may lead to serious medical and social consequences and is associated with increased morbidity, mortality, and high health care costs, the issue should be precisely addressed, and preventive strategies should be developed. An emerging body of evidence suggests that anesthesia and surgery have an undesirable effect on long-term cognitive function in the elderly; however, there are no convincing human data to support this correlation. Thus, the effects of anesthesia and surgery on cognition and on the natural course of underlying neurodegenerative diseases are not clear. This review presents a systemic and comprehensive clinical view of cognitive decline following anesthesia and surgery. It aims to emphasize the pathophysiological processes and risk factors of aging and potential anesthesia- and surgery-related neurodegeneration, since defining high-risk patients and preventing the problem can provide benefits for patients with neurodegenerative disease

Özet

1950'lerden beri cerrahi ve anestezi uygulanan yaşlı hastalarda postoperatif bilişsel değişiklikler yaşanması endişe kaynağı olmuştur. Yaşlılarda postoperatif bilişsel bozulma, ciddi tıbbi ve sosyal sonuçlara neden olabilir ve morbidite, mortalite ve yüksek sağlık masrafları ile ilişkili olduğundan, konu tam olarak ele alınmalı ve önleyici stratejiler geliştirilmelidir. Ortaya konan kanıtlar, anestezinin ve ameliyatın yaşlılarda uzun süreli bilişsel işlev üzerinde istenmeyen bir etkiye sahip olduğunu göstermektedir. Bununla birlikte, bu korelasyonu desteklemek için inandırıcı insan verileri mevcut değildir. Bu nedenle, anestezi ve cerrahinin kognisyon ve nörodejeneratif hastalıkların doğal seyri üzerindeki etkileri açık değildir. Bu derlemede, anestezi ve ameliyat sonrasında bilişsel bozulmanın sistemik ve kapsamlı bir klinik görünümü sunulmaktadır. Derleme, yaşlılık, potansiyel anestezi ve cerrahi ile ilişkili nörodejenerasyonun patofizyolojik süreçlerini ve risk faktörlerini vurgulamayı amaçlıyor, çünkü yüksek riskli hastaları tanımlamak ve sorunun engellenmesi nörodejeneratif hastalığı olan hastalar için fayda sağlayabilir

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Cite This Article

İNAN, G., ŞATIRLAR, Z. Ö. (2022). YAŞLI BEYİNDE ANESTEZİ VE CERRAHİNİN SONUÇLARI ÜZERİNE BİR KLİNİK İNCELEME: “AYIN KARANLIK YÜZÜ”. Türk Geriatri Dergisi, Cilt: 21 - Sayı: 1, 87–99. https://ajindex.com/articles/623660

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