Journals / Türk Geriatri Dergisi / 2019 / Cilt: 22 - Sayı: 3

EVALUATION OF TEAR FILM LAYER AND MEIBOMIAN GLAND MORPHOLOGY IN GERIATRIC PATIENTS WITH CHRONIC BLEPHARITIS

KRONIK BLEFARITLI GERIATRIK HASTALARDA MEIBOMIAN BEZ MORFOLOJISI VE GÖZ YAŞI FILM TABAKASININ DEĞERLENDIRILMESI

Pages
324–330
Publication Date
2022-11-04
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In these patients, meibomian gland atrophy score isconsidered as a valuable method consistent with clinical findings.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: To investigate the changes in meibomian gland morphology and theireffects on tear parameters in geriatric patients with chronic blepharitis.Materials and Method: The study included 70 eyes of 35 healthy subjects in the controlgroup and 60 eyes of 30 patients with chronic blepharitis.
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Key Findings & Data:Invasive tear break up time was performed 1 min after putting asingle drop of fluorescein in all patients.Results: The mean age of the patients was 74.6±7.1 and 73.9±6.3 years in the blepharitisand control groups, respectively (p = 0.669).
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Conclusion & Impact:In these patients, meibomian gland atrophy score isconsidered as a valuable method consistent with clinical findings.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: To investigate the changes in meibomian gland morphology and theireffects on tear parameters in geriatric patients with chronic blepharitis.Materials and Method: The study included 70 eyes of 35 healthy subjects in the controlgroup and 60 eyes of 30 patients with chronic blepharitis. The patients were requested tocomplete a symptom questionnaire [Ocular surface disease index] before clinical examination.Non-contact meibography and non-invasive tear break-up time tests were performed with theSirius Scheimpflug camera. Meibography scoring (Meiboscore) of the upper and lower lids wasperformed in all patients. Invasive tear break up time was performed 1 min after putting asingle drop of fluorescein in all patients.Results: The mean age of the patients was 74.6±7.1 and 73.9±6.3 years in the blepharitisand control groups, respectively (p = 0.669). The total meiboscore, non-invasive first andmean tear break up time, invasive tear break up time, and ocular surface disease index scorewere 3.6±1.7, 8.0±4.8, 9.7±4.0, 7.1±3.0, and 27.4±11.7, respectively, for the blepharitis groupand 3.0±1.4, 10.4±5.7, 11.4±5.0, 8.6±3.1, and 18.0±6.4, respectively for the control group(respectively p = 0.03, 0.01, 0.03, 0.00, 0.00).Conclusion: Chronic blepharitis in patients aged ≥65 years was associated withmorphological changes in meibomian gland, decreased tear break up time, and increasedocular surface disease index scores. In these patients, meibomian gland atrophy score isconsidered as a valuable method consistent with clinical findings.

Özet

Giriş: Bu çalışmada kronik blefariti olan geriatrik hastalarda meibomian bez morfolojisini ve bunun gözyaşı parametrelerine olan etkisini değerlendirmek amaçlanmıştır. Gereç ve Yöntem: Bu çalışmaya 30 kronik blefaritli hastanın 60 gözü ve kontrol grubuna 35 sağlıklı bireyin 70 gözü dahil edildi. Klinik muayene öncesinde tüm hastalardan semptom anketini tamamlaması istendi [Oküler yüzey hastalık indeksi]. Non-kontakt meibografi ve noninvaziv göz yaşı kırılma zamanı ölçümleri Sirius Scheimpflug Camera ile yapıldı. Tüm olgularda her iki gözde alt ve üst kapaklarda meibografi skorlaması (Meiboskor) yapıldı. Tüm olgularda invaziv gözyaşı kırılma zamanı bir damla floresein damlatıldıktan 1 dakika sonra ölçüldü. Bulgular: Çalışmaya alınan olgularda yaş ortalaması blefarit grubunda 74.6±7.1, kontrol grubunda 73.9±6.3 yıldı (p = 0.669). Sırasıyla toplam meiboskor, non-invaziv ilk ve ortalama gözyaşı kırıma zamanı, invaziv gözyaşı kırılma zamanı, oküler yüzey hastalık indeksi skoru blefarit grubunda 3.6±1.7, 8.0±4.8, 9.7±4.0, 7.1±3.0, 27.4±11.7 iken kontrol grubunda 3.0±1.4, 10.4±5.7, 11.4±5.0, 8.6±3.1, 18.0±6.4 bulundu (sırasıyla p = 0.03, 0.01, 0.03, 0.00, 0.00). Sonuç: Altmışbeş yaş ve üzerindeki kronik blefaritli hastalarda meibomian bezlerde morfolojik değişiklikler, azalmış gözyaşı kırılma zamanı ve artmış oküler yüzey hastalık indeksi skorları olduğu görülmektedir. Bu hastalarda, meibomian bez atrofi skorunun klinik bulgularla uyumlu değerli bir yöntem olduğu düşünüldü.

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Cite This Article

TABAKÇI, B. N., TANRIVERDİ, C. (2022). EVALUATION OF TEAR FILM LAYER AND MEIBOMIAN GLAND MORPHOLOGY IN GERIATRIC PATIENTS WITH CHRONIC BLEPHARITIS. Türk Geriatri Dergisi, Cilt: 22 - Sayı: 3, 324–330. https://ajindex.com/articles/623632

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