Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2011 / Cilt: 45 - Sayı: 4

Genitourinary infections in female patients with psoriasis: Demographic and clinical features

Psoriyazisli kadın olgularda genitoüriner infeksiyonlar; Demografik ve klinik özellikler

Pages
174–178
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

It was found that the patients with GUI had lower mean age of psoriasis onset, shorter mean duration of the last exacerbation and higher values of mean PASI compared to those without GUI.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: It has been reported that the focal infections may trigger the formation and/or exacerbation of psoriasis lesions.
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Key Findings & Data:Materials and methods: In this retrospective study, the files of 144 female psoriasis vulgaris inpatients were evaluated for clinical type of psoriasis, demographic data, psoriasis area and severity index (PASI), and accompanying GUIs.
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Conclusion & Impact:It was found that the patients with GUI had lower mean age of psoriasis onset, shorter mean duration of the last exacerbation and higher values of mean PASI compared to those without GUI.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Design: It has been reported that the focal infections may trigger the formation and/or exacerbation of psoriasis lesions. Although it is known that the most frequent association is with throat infection, it is emphasized that urinary tract infections should be considered as a triggering factor due to improvement of psoriatic lesions after treatment of active or asymptomatic urinary tract infection in some cases. The aim of our study was to evaluate the frequency of genitourinary infection (GUI) and to compare the clinical and demographic features of cases with and without GUI. Materials and methods: In this retrospective study, the files of 144 female psoriasis vulgaris inpatients were evaluated for clinical type of psoriasis, demographic data, psoriasis area and severity index (PASI), and accompanying GUIs. Clinically, the patients with plaque psoriasis were defined as “stable” psoriasis, while those with guttate psoriasis or with flare-up of guttate psoriasis in case of plaque psoriasis were defined as “active” psoriasis. Results: Out of a total of 144 psoriasis patients, 93 (64.4%) were in the active group and 51 (35.4%) were in the stable group. Of all the patients, 48 (33.3%) had GUI. Thirty-one (21.5%) patients had urinary tract infection, 23 (16%) had vaginitis and 5 (3.5%) patients had cervicitis. It was found that the patients with GUI had lower mean age of psoriasis onset, shorter mean duration of the last exacerbation and higher values of mean PASI compared to those without GUI. In patients with active psoriasis, the frequency of GUI was higher (36.6%) than in the stable group (27.5%), but statistically significant difference between them was not determined. Conclusion: We assumed that it would be beneficial to investigate GUI in both active and stable psoriasis cases, especially in patients who had recently suffered an exacerbation or had high clinical severity scores. (Turk derm 2011; 45: 174-8)

Özet

Amaç: Fokal infeksiyonların psoriyasis lezyonlarının oluşumu ve/veya alevlenmesini tetikleyebildiği bildirilmiştir. En sık boğaz infeksiyonları ile ilişkisi bilinmekle birlikte, bazı olgularda aktif veya asemptomatik idrar yolu infeksiyonunun tedavisi ile psoriyazis lezyonlarında da düzelme gözlenmesi üzerine idrar yolu infeksiyonlarının tetikleyici faktör olarak dikkate alınması gerektiği vurgulanmıştır. Bu çalışmada psoriyazis vulgarisli kadın olgularda genitoüriner infeksiyon (GÜİ) sıklığının değerlendirilmesi ve GÜİ olan olgulardaki klinik ve demografik özelliklerin olmayan olgularla karşılaştırılması amaçlanmıştır. Gereç ve yöntemler: Retrospektif olarak planlanmış çalışmamızda kliniğimizde yatan psoriyazis vulgarisli 144 kadın olgunun dosyası psoriyazis klinik tipi, demografik veriler, psoriyazis alan şiddet indeksi ve eşlik eden GÜİ’ları açısından taranmıştır. Klinik olarak plak psoriyazisli olgular “stabil”, guttat psoriyazisli veya guttat saçılımları olan plak psoriyazisli olgular ise “aktif” psoriyazis olarak tanımlanmıştır. Bulgular: Toplam 144 psoriyazis olgusunun 93 (%64,6)’ünün aktif psoriyazis, 51 (%35,4)’inin ise stabil psoriyazis klinik özelliklerini taşıdığı saptanmıştır. Olguların 31 (%21,5)’inde idrar yolu infeksiyonu, 23 (%16)’ünde vajinit ve 5 (%3,5)’inde servisit olmak üzere toplam 48 (%33,3) olguda GÜİ varlığı belirlenmiştir. GÜİ saptanan olgularda GÜİ olmayanlara göre ortalama psoriasis başlangıç yaşının daha düşük, son alevlenme süresinin daha kısa ve psoriyazis alan şiddet indeksi değerlerinin daha yüksek olduğu gösterilmiştir. Aktif psoriyazisli olgularda %36.6 olarak saptanan GÜİ sıklığının stabil psoriyazisli olgulara (%27,5) göre daha fazla olduğu ancak istatistiksel olarak anlamlı olmadığı gösterilmiştir. Sonuç: Hem aktif hem de stabil psoriyaziste özellikle yakın zamanda alevlenme geçirmiş veya klinik şiddet skorları yüksek olan olgularda GÜİ araştırılmasının yararlı olacağı kanaatindeyiz. (Türk derm 2011; 45: 174-8)

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Cite This Article

ÖZBAĞÇIVAN, Ö., AKARSU, S., İLKNUR, T., FETİL, E., GÜNEŞ, A. T., CANBAZ, C. A., ÇARŞANBALI, S. (2022). Genitourinary infections in female patients with psoriasis: Demographic and clinical features. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 45 - Sayı: 4, 174–178. https://ajindex.com/articles/622390

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