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Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2001 / Cilt: 35 - Sayı: 2

Long-term outcome of terbinafine and itraconazole in the treatment of onychomycosis

Terbinafin ve itrakonazolün onikomikoz tedavisinde uzun süreli izlem sonuçları

Zeynep DEMİRÇAY
Oya GÜRBÜZ
Raheleh KHALİLAZAR
Pages
125–128
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: At week 48, overall success rates were 95.6% for terbinafine versus 65% for itraconazole (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background and design: The aim of this study was to compare the efficacy of terbinafine and itraconazole in toenail onychomycosis after a long term follow-up of two years.
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Key Findings & Data:Materials and methods: A total of 72 patients received either terbinafine 250 mg/day for 12 weeks or itraconazole 200 mg/day for 16 weeks.
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Conclusion & Impact:Results: At week 48, overall success rates were 95.6% for terbinafine versus 65% for itraconazole (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and design: The aim of this study was to compare the efficacy of terbinafine and itraconazole in toenail onychomycosis after a long term follow-up of two years. Materials and methods: A total of 72 patients received either terbinafine 250 mg/day for 12 weeks or itraconazole 200 mg/day for 16 weeks. Clinical symptoms and mycologic outcome were assessed in weeks 4, 8,12,16, 24, 36, 48, 96. Forty three patients who completed the study were analysed. Results: At week 48, overall success rates were 95.6% for terbinafine versus 65% for itraconazole (p

Özet

Ayak tırnağı mantarı tedavisinde terbinafin ve İtrakonazolün uzun süreli İzlem sonrasındaki başarıları araştırıldı. Çalışmaya direkt mikroskopik incelemesi ve kültür sonucu pozitif olan toplam 72 hasta alındı. Bir hasta yan etki nedeniyle, 28 hasta kontrol muayenelerine gelmediği için çalışma dışı bırakıldı. Doksanaltı hafta boyunca izlenen 43 hastada, terbinafin (23 hasta), ve itrakonazol (20 hasta) tedavilerinin 48., 96. hafta sonuçları karşılaştırıldı. Tedavinin 48.haftasında terbinafin hastaların %95.6'sında, itrakonazol %65'inde başarılı bulundu (p

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Cite This Article

DEMİRÇAY, Z., GÜRBÜZ, O., KHALİLAZAR, R. (2022). Long-term outcome of terbinafine and itraconazole in the treatment of onychomycosis. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 35 - Sayı: 2, 125–128. https://ajindex.com/articles/622300

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