Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2002 / Cilt: 36 - Sayı: 3

A case of malignant eccrine poroma on the leg

Bacak lokalizasyonlu bir malin ekrin poroma olgusu

Pages
218–220
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Two years of follow-up revealed no recurrence or metastasis of the tumour.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Malignant eccrine poroma is an uncommon neoplasm which shows differentiation throughout intraepidermal and dermal duct of eccrine sweat gland.
📊
Key Findings & Data:A case of malignant eccrine poroma on the left leg in a 70-year-old female is described with a review of the literature.
💡
Conclusion & Impact:Two years of follow-up revealed no recurrence or metastasis of the tumour.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Malignant eccrine poroma is an uncommon neoplasm which shows differentiation throughout intraepidermal and dermal duct of eccrine sweat gland. A case of malignant eccrine poroma on the left leg in a 70-year-old female is described with a review of the literature. Following the surgical excision, the lesion was evaluated by routine histopathology and immuno-histochemical staining. In the histopathological evaluation, the tumour cells arise from epidermis extended into the dermis forming chordons and islands. The tumour cells showed nuclear atypia, pleomorphism and abnormal mitotic figures. In addition, dyskeratotic cells and ductal differentiation areas were seen among tumour cells, immunohistochemically, carcinoembryonic antigen was positive in the areas of ductal differentiation. Two years of follow-up revealed no recurrence or metastasis of the tumour.

Özet

Malin ekrin poroma, ekrin ter bezinin intraepidermal ve dermal kanalı yönünde diferensiasyon gösteren nadir bir neoplazidir. 70 yaşında sol bacağında malin ekrin poroma saptanan kadın hasta literatür bilgileri ışığında gözden geçirilerek tanımlanmıştır. Lezyon cerrahi eksizyon sonrasında rutin histopatoloji ve immunhistokimyasal boyama ile incelendi. Histopatolojik değerlendirmede tümör hücreleri epidermisten başayan kordonlar ve adalar oluşturmak suretiyle dermise doğru uzanmaktaydı. Tümör hücreleri nükleer atipi, pleomorfizm ve anormal mitoz göstermekteydi. Ayrıca tümör hücreleri arasında duktal diferensiasyon sahaları ve diskeratotik hücreler göz/endi, immunhistokimyasal olarak ise duktal diferensiasyon alanlarında karsinoembriyonik antijen pozitif boyanma özelliği gösterdi, iki yıllık takip sonucu metastaz veya rekürrens bulgusu saptanmadı.

🔖

Cite This Article

CEYLAN, C., KANDİLOĞLU, G., KAZANDI, A., ERBOZ, S., ÖZDEMİR, F. (2022). A case of malignant eccrine poroma on the leg. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 36 - Sayı: 3, 218–220. https://ajindex.com/articles/622295

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Damato MS, Patterson RH, Guccion JG, White JC, Krasnow SH: Porocarcinoma of the heel. A case report with unusual histologic features. Cancer 1996; 78: 751-757
  2. Maeda T, Mori H, Matsuo T, Nakagawa J, Yamauchi: Malignant eccrine poroma with multipl visceral metastases: report of a case with autopsy findings. J Cutan Pathol 1996; 23: 571 -574
  3. Pinkus H, Mehregan AH, Monroe M: Epidermotropic eccrine carcinoma. A case combining features of eccrine poroma and Paget's dermatosis. Arch Dermatol 1963; 88: 597
  4. MacKie RM: Skin Cancer. Second edition, London, Toppan Com. 1996:266
  5. Odom RB, James WD, Berger TG: Diseases of the Skin. Ninth edition. Philadelphia, WB Saunders Company 2000: 849-850
  6. Galadari E, Mehregan AH, Lee KC: Malignant transformation of eccrine tumors. J Cutan Pathol 1987; 14(1): 15-22
  7. Snow SN, Reizner GT: Eccrine porocarcinoma of the face. J Am Acad Dermatol 1992; 27: 306-311
  8. Puttick L, İnce P, Comaish JS: Three cases of eccrine porocarci¬ noma. Br J Dermatol 1986; 115(1):111-6
  9. Bottles K, Sagebiel R, McNuth NS, Jensen B, Deveney K: Malign eccrine poroma: Case report and review of the literature. Cancer 1984; 53: 1579-1585
  10. Johnson RC, Rosenmeier GJ, Keeling JH: A painful step. Arch Dermatol 1992; 128: 1533-8, 11. Pernia LR, Guzman-Steih G, Miller HL: Surgical treatment of an aggressive metastasized eccrine poroma. Ann Plast Surg 1993;30(3): 257-9
  11. Dummer R, Becker JC, Boser B, Hartmann AA, Gunter G: Succesful therapy of metastatic eccrine poroma using perilesional interferon alfa and interleukin 2. Arch Dermatol 1992; 128: 1127-8
  12. Barzi AS, Ruggeri S, Recchia F, Bertoldi I: Malignant metastatic eccrine poroma. Proposal for a new therapeutic protocol. Dermatol Surg 1997;23(4): 267-72
  13. Roach M: A malignant eccrine poroma responds to isotretinoin (13-cis retinoic acid). Ann Int Med 1983;99(4): 486-8
  14. Freidland M, Bajracharya A, Arlin A: Malignant eccrine poroma and isotretinoin (letter), ann Int Med 1984; 100: 614.