Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2015 / Cilt: 49 - Sayı: 2

Insulin resistance and metabolic syndrome in female androgenetic alopecia

Androgenetik alopesili kadınlarda insülin direnci ve metabolik sendrom

Pages
134–138
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The difference between the groups was not statistically significant (p>0.05).

📌 3 Key Takeaways

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Objective & Hypothesis:Background and design: In this study, we aimed to identify whether there was an association of insulin resistance and metabolic syndrome with androgenetic alopecia (AGA) in reproductive women.
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Key Findings & Data:Materials and methods: We investigated insulin resistance and metabolic syndrome, which is known to be associated with insulin-resistance, in 55 females with AGA (Ludwig I and above) who were under 45 years of age and 50 age-matched woman without AGA.
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Conclusion & Impact:The difference between the groups was not statistically significant (p>0.05).
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and design: In this study, we aimed to identify whether there was an association of insulin resistance and metabolic syndrome with androgenetic alopecia (AGA) in reproductive women. Materials and methods: We investigated insulin resistance and metabolic syndrome, which is known to be associated with insulin-resistance, in 55 females with AGA (Ludwig I and above) who were under 45 years of age and 50 age-matched woman without AGA. We used homeostasis model assessment (HOMA) index and quantitative insulin sensitivity check index (QUICKI) to identify insulin resistance. The cut-off value for HOMA was accepted as 2.7. The diagnosis of metabolic syndrome was established using the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Results: Serum fasting blood glucose levels were significantly higher in females with AGA than in controls (p0.05). The two groups were also compared for the levels of QUICKI. The mean levels of QUICKI in patient control groups were 0.36±0.04 and 0.36±0.03, respectively. The difference between the groups was not statistically significant (p>0.05).

Özet

Amaç: Bu çalışmada doğurganlık çağındaki kadınlarda androgenetik alopesi (AGA) ile insülin direnci ve metabolik sendrom arasında ilişki olup olmadığını gösterebilmeyi amaçladık. Gereç ve Yöntem: Çalışmada 45 yaş altı, Ludwig sınıflamasına göre 1. derece ve üzerinde AGAlı 55 kadın hasta ile aynı yaş aralığında AGAsı olmayan 50 kadında insülin direnci ve insülin direnci ile ilişkisi bilinen metabolik sendrom varlığını araştırdık. İnsülin direncini hesaplamada homeostasis model assessment (HOMA) indeksi ile quantitative insülin sensitivity check index (QUICKI) yöntemlerini kullandık. Metabolik sendrom tanısı National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) kriterlerine göre konuldu. Bulgular: Açlık kan şekeri düzeyleri ortalaması hasta grubunda kontrol grubuna göre istatistiksel olarak daha yüksek saptandı (p0,05). Her iki grup QUICKI değerleri açısından da karşılaştırıldı. AGAlı grupta ortalama QUICKI değeri 0,36±0,04 iken, kontrol grubunda ortalama QUICKI değeri 0,36±0,03 bulundu. Gruplar arası fark istatiksel olarak anlamlı bulunmadı (p>0,05). Son olarak iki grup NCEP ATP III kriterleri baz alınarak metabolik sendrom varlığı açısından karşılaştırıldığında, androgenetik alopesili hasta grubundaki 55 olgunun 5inde (%9,1) metabolik sendrom saptanırken, kontrol grubunda metabolik sendrom saptandı. Gruplar arası farklılık istatiksel olarak anlamlı bulunmadı (p

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Cite This Article

SALMAN, S. (2022). Insulin resistance and metabolic syndrome in female androgenetic alopecia. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 49 - Sayı: 2, 134–138. https://ajindex.com/articles/622256

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