Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2004 / Cilt: 38 - Sayı: 2

Unilateral axillary acanthosis nigricans associated with acral vitiligo

Akral vitiligoya eşlik eden tek taraflı aksiller akantozis nigrikans

Pages
143–145
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the clinical and laboratory findings, nevoid acantosis nigricans was diagnosed, and we concluded that our case was another example of acantosis nigricans associated with vitiligo.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acanthosis nigricans is characterized by hyperpigmented, velvety and verrucous plaques with a predilection for flexures.
📊
Key Findings & Data:Here, we report a 21-year-old woman with unilateral axillary acanthosis nigricans associated with acral vitiligo lesions on both of her hands.
💡
Conclusion & Impact:According to the clinical and laboratory findings, nevoid acantosis nigricans was diagnosed, and we concluded that our case was another example of acantosis nigricans associated with vitiligo.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Acanthosis nigricans is characterized by hyperpigmented, velvety and verrucous plaques with a predilection for flexures. It has been associated with endocrine disturbances, malignancies, administration of certain drugs, genetic syndromes and autosomal dominant transmission. The association of acanthosis nigricans with vitiligo has rarely been described. Acanthosis nigricans is always bilateral; unilateral localisation of the lesions is considered to be a nevoid process. Here, we report a 21-year-old woman with unilateral axillary acanthosis nigricans associated with acral vitiligo lesions on both of her hands. Other intertriginous areas were intact. She was not obese and did not describe drug intake or family history of similar skin lesions. Routine hematologic, biochemical and radiologic investigations showed no evidence of endocrinologic disorder or malignancy. According to the clinical and laboratory findings, nevoid acantosis nigricans was diagnosed, and we concluded that our case was another example of acantosis nigricans associated with vitiligo.

Özet

Akantozis nigrikans kıvrım bölgelerine yerleşme eğiliminde olan hiperpigmentli, kadifemsi ve verrüköz plaklarla karakterizedir. Hastalık endokrin bozukluklar, bazı ilaçlar, genetik sendromlar ve malinitelerle ilişkili olabileceği gibi, otozomal dominant geçişli kalıtsal bir tablo olarak da görülebilir. Akantozis nigrikans ve vitiligo beraberliğini bildiren az sayıda yayın bulunmaktadır. Akantozis nigrikans lezyonları hemen her zaman çift taraflı ve simetrik yerleşimlidir. Tek taraflı yerleşim nevoid bir gelişim şeklinde değerlendirilmektedir. Burada, her iki el sırtında vitiligo lezyonları ve tek taraflı aksiller akantozis nigrikansı bulunan 21 yaşında bir kadın olgu sunuldu. Diğer kıvrım bölgelerinde benzer lezyonların olmadığı hastada obezite, ilaç alımı ve aile öyküsü yoktu. Yapılan biyokimyasal, hematolojik ve radyolojik incelemelerde endokrin bozukluk veya malinite bulgularına rastlanmadı. Klinik ve laboratuar bulguları ışığında nevoid akantozis nigrikans tanısı alan olgu, vitiligo ile akantozis nigrikans birlikteliğinin yeni bir örneği olarak değerlendirildi.

🔖

Cite This Article

GÖKTAY, F., GÜNDÜZ, S., MANSUR, A. T. (2022). Unilateral axillary acanthosis nigricans associated with acral vitiligo. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 38 - Sayı: 2, 143–145. https://ajindex.com/articles/622249

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Schwartz RA. Acanthosis nigricans. J Am Acad Dermatol 1994;31:1-19
  2. Kang S, Sober AJ. Disturbances of Melanin Pigmentation. In: Moschella SL, Hurley HJ, eds. Dermatology, 3th ed. Philadelphia:WB. Saunders Company, 1992:1442-1474
  3. Maldonado RR. Diseases of Pigment Change. In: Maldonado RR, Parish LC, Beare JM, eds. Textbook of Pediatric Dermatology, 1th ed. Philadelphia: Grune&Stratton, Inc, 1989:243-267
  4. Curth HO. Unilateral epidermal nevus resembling acanthosis nigricans. Br J Dermatol 1976; 95:433-436
  5. Blume-Peytavi U, Spieker T, Reupke H, Orfanos CE. Generalized acanthosis nigricans with vitiligo. Acta Derm Venereol (Stoch)1996; 76:377-380
  6. Harman M, Akdeniz S, Çetin H, Tuzcu A. Acanthosis nigricans with vitiligo and insulin resistance. Br J Dermatol 2000; 143:899-900
  7. Horn TD. Non-inflammatory disorders of the skin. In:Pathology of the Skin. Farmer ER, Hood AF, eds. London, Appleton&Lange, 1990, p.397-407
  8. Ackerman AB, Mendonça AMN, Guo YD. Differential Diagnosis in Dermathopathology I, 2th ed. Malvern: Lea&Febiger, 1992:94-97
  9. Scallreuter KU, Lemke R, Brandt O, Schwartz R et al. Vitiligo and other diseases: coexistence or true association? Dermatology 1994; 188:269-275.