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Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2007 / Cilt: 41 - Sayı: 2

Tuberculin skin reactivity and T-lymphocyte subgroups in patients with chronic idiopathic urticaria

Kronik idiyopatik ürtikerli olgularda tüberkülin deri testi yanıtı ve T-lenfosit alt grupları

Burhan ENGİN
Mustafa ÖZDEMİR
İnci MEVLİTOĞLU
Pages
54–56
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: These data provided that ASST does not seem to be associated with TST reactivity and T-lymphocyte subsets.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: It has been demonstrated that the autologous serum skin test (ASST) has an important role in clinical test for detection of autoimmune-based urticaria.
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Key Findings & Data:MATERIALS-METHODS: We examined 68 patients and 37 control subjects, performed ASST and tuberculin skin reactivity (TST) and measured T-lymphocyte subsets.
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Conclusion & Impact:CONCLUSION: These data provided that ASST does not seem to be associated with TST reactivity and T-lymphocyte subsets.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and Design: It has been demonstrated that the autologous serum skin test (ASST) has an important role in clinical test for detection of autoimmune-based urticaria. The aim of this study was to evaluate the ASST and cell immunity modifiers. MATERIALS-METHODS: We examined 68 patients and 37 control subjects, performed ASST and tuberculin skin reactivity (TST) and measured T-lymphocyte subsets. RESULTS: ASST was significantly positive in urticaria patients compared to control subjects. Thirty-two patients had positive TST reactivity. T-lymphocyte subsets were as follows: CD4: %41.3±3.4, CD8: %34±6.5, CD4/CD8: %1.2, CD3: %66±8.8. ASST was not related to the TST reactivity and T-lymphocyte subsets. CONCLUSION: These data provided that ASST does not seem to be associated with TST reactivity and T-lymphocyte subsets.

Özet

AMAÇ: Otolog serum testinin (OST) otoimmün ürtiker tanısında önemli bir rol oynadığı bilinmektedir. Bu çalışmada OST ve hücresel immünite belirleyicilerinin ilişkili olup olmadıklarını araştırdık. GEREÇ-YÖNTEM: Bu amaçla 68 hasta ve 37 kontrol grubuna OST ve tüberkülin deri testi (TDT) uygulandı ve T-lenfosit alt grupları ölçüldü. BULGULAR: OST kontrol grubuna göre ürtikerli hastalarda anlamlı olarak pozitif bulundu. TDT yanıtı 32 hastada pozitifti. T-lenfosit alt grupları CD4: %41.3±3.4, CD8: %34±6.5, CD4/CD8: %1.2, CD3: %66±8.8 şeklindeydi. SONUÇ: Sonuç olarak kronik ürtiker hastalarında OST’nin, TDT yanıtı ve T-lenfosit alt grupları ile ilişkili olmadığını belirledik.

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Cite This Article

ENGİN, B., ÖZDEMİR, M., MEVLİTOĞLU, İ. (2022). Tuberculin skin reactivity and T-lymphocyte subgroups in patients with chronic idiopathic urticaria. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 41 - Sayı: 2, 54–56. https://ajindex.com/articles/622130

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