Lichen planus pemphigoides associated with bisoprolol

Objective & Hypothesis:Lichen planus pemphigoides (LPP) is a disease characterized by tense bullae arising on lichen planus papules and on clinically uninvolved skin, lichenoid infiltration and subepidermal bulla in histopathology, and linear deposits of IgG and C3 along basal membrane zone on direct immunofluorescence.

📊

Key Findings & Data:This rare bullous dermatosis is usually idiopathic.

💡

Conclusion & Impact:We reported a 35-year-old woman with LPP possibly induced by bisoprolol.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Lichen planus pemphigoides (LPP) is a disease characterized by tense bullae arising on lichen planus papules and on clinically uninvolved skin, lichenoid infiltration and subepidermal bulla in histopathology, and linear deposits of IgG and C3 along basal membrane zone on direct immunofluorescence. This rare bullous dermatosis is usually idiopathic. However, in a few cases in the literature, it has been reported to be induced by hepatitis B, malignancies, phototherapy and some medications such as ramipril, captopril, cinnarizine and simvastatin. We reported a 35-year-old woman with LPP possibly induced by bisoprolol.

Özet

Liken planus pemfigoides (LPP) klinik olarak gerek liken planus lezyonları üzerinde gerekse tutulmamış deri bölgelerinde yerleşimli gergin büller ile karakterize iken, histopatolojik olarak likenoid infiltrasyon ve subepidermal bül oluşumu yanında direkt immünofloresan incelemede bazal membran boyunca lineer Ig G ve C3 birikimi ile karakterize bir hastalıktır. Nadir görülen bu büllöz dermatoz genellikle idiyopatik olmakla birlikte literatürde hepatit B, maliniteler, fototerapi ve ramipril, kaptopril, sinnarizin ve simvastatin gibi bazı ilaçlar ile tetiklenen az sayıda olgu bildirilmiştir. Burada bisoprolol kullanımı ile tetiklendiği düşünülen LPP?li 35 yaşında bir kadın olgu sunulmaktadır.

🔖

Cite This Article

İLKNUR, T., AKARSU, S., FETİL, E., LEBE, B., CANBAZ, C. A., ÇARŞANBALI, S. (2022). Lichen planus pemphigoides associated with bisoprolol. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 46 - Sayı: 2, 101–103. https://ajindex.com/articles/621962

📄 Full Text PDF Viewer

Open in New Tab ↗

↗New Tab

📄

PDF görüntüleyici hazırlanıyor...

References (17)

Bouloc A, Vignon-Pennamen MD, Caux F, et al: Lichen planus pemphigoides is a heterogeneous disease: a report of five cases studied by immunoelectron microscopy. Br J Dermatol 1998;138:972-80
Swale VJ, Black MM, Bhogal BS: Lichen planus pemphigoides: two case reports. Clin Exp Dermatol 1998;23:132-5
Şentürk N, Seraslan G, Bükülmez G, et al: Liken planus pemfigoides. Turkderm 2001;35:334-6
Günaştı S, Tuncer İ, Hasbay B, Denli Y, Uzun S: Liken planus pemfigoidesin klinik, histolojik ve immünoflöresan özellikleri: iki olgu sunumu. Turk J Dermatol 2010;4:25-8
Flageul B, Hassan F, Pinquier L, Blanchet-Bardon C, Dubertret L: [Lichen pemphigoid associated with developing hepatitis B in a child]. Ann Dermatol Venereol 1999;126:604-7
Hamada T, Fujimoto W, Okazaki F, et al: Lichen planus pemphigoides and multiple keratoacanthomas associated with colon adenocarcinoma. Br J Dermatol 2004;151:252-4
Kuramoto N, Kishimoto S, Shibagaki R, Yasuno H: PUVA-induced lichen planus pemphigoides. Br J Dermatol 2000;142:509-12
Maoz KB, Brenner S: Lichen planus pemphigoides triggered by narrowband UVB, paracetamol, and ibuprofen, with autoantibodies to 130kDa antigen. Skinmed 2008;7:33-6
Miyagawa S, Ohi H, Muramatsu T, et al: Lichen planus pemphigoides-like lesions induced by cinnarizine. Br J Dermatol 1985;112:607-13
Ogg GS, Bhogal BS, Hashimoto T, Coleman R, Barker JN: Ramipril-associated lichen planus pemphigoides. Br J Dermatol 1997;136:412-4
Demirçay Z, Baykal C, Demirkesen C: Lichen planus pemphigoides: report of two cases. Int J Dermatol 2001;40:757-9
Stoebner PE, Michot C, Ligeron C: [Simvastatin-induced lichen planus pemphigoides]. Ann Dermatol Venereol 2003;130:187-90
Zhu YI, Fitzpatrick JE, Kornfeld BW: Lichen planus pemphigoides associated with ramipril. Int J Dermatol 2006;45:1453-5
Ben Salem C, Chenguel L, Ghariani N: Captopril-induced lichen planus pemphigoides. Pharmacoepidemiol Drug Saf 2008;17:722-4
Xu HH, Xiao T, He CD, et al: Lichen planus pemphigoides associated with Chinese herbs. Clin Exp Dermatol 2009;34:329-32
Flageul B, Foldes C, Wallach D, Vignon-Pennamen MD, Cottenot F: Captoprilinduced lichen planus pemphigoides with pemphigus-like features. A case report. Dermatologica 1986;173:248-55
Halevy S, Shai A: Lichenoid drug eruptions. J Am Acad Dermatol 1993;29:249-55.