Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2012 / Cilt: 46 - Sayı: 4

The sensitization rates of Hymenoptera venom in Mersin region

Mersin yöresinde Hymenoptera venom duyarlılık oranları

Pages
196–201
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, Hymenoptera venom allergy may contribute to health problems, significantly in this part of the country.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: Allergic reactions to Hymenoptera venoms are significant health problems because of their serious outcomes.
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Key Findings & Data:The aim of this study was to investigate the sensitization rates of Hymenoptera venoms (an indirect measure of Hymenoptera venom allergy) in Mersin region.
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Conclusion & Impact:Therefore, Hymenoptera venom allergy may contribute to health problems, significantly in this part of the country.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and Design: Allergic reactions to Hymenoptera venoms are significant health problems because of their serious outcomes. The aim of this study was to investigate the sensitization rates of Hymenoptera venoms (an indirect measure of Hymenoptera venom allergy) in Mersin region. Materials and Methods: In this study, we investigated the sensitization rates among 209 volunteers (86 males, 123 females, mean age: 38.4 years) using questionnaires, total IgE determination with nephelometric method and phadiotop determinations with fluoroimmunoassay, epidermal/intradermal testing with Apidae, Vespidae and Polistes venom extracts. Results: Sensitization rate to venoms of all three species were 21.0% among 209 subjects. Sensitization rate to more than one species simultaneously was 52.3% among Hymenoptera-sensitive subjects. With the aid of questionnaires we found that sting reactions were “normal reactions” in 80%, “large local reactions” in 11.0% and “systemic reactions” in 9% of the subjects. The rate of positive skin tests was 23.5% among the subjects who described large local reactions and 21.5% among the subjects who described systemic reactions. There were no significant difference in the sensitization rates between males and females, in subjects stratified by age, subjects with elevated and normal total IgE values, subjects with positive and negative phadiotop determinations subjects living in urban and suburban areas and between subjects with respect to sting number or time elapsed since the last sting or the varieties of sting reactions. Conclusion: Although low in titer, the sensitization rates to hymenoptera venoms were significantly high in Mersin region. Therefore, Hymenoptera venom allergy may contribute to health problems, significantly in this part of the country.

Özet

Amaç: Arı venomlarına karşı gelişen alerjik reaksiyonlar ciddi sonuçlarının olması nedeniyle önemli bir sağlık sorunu oluşturmaktadır. Bu çalışmayı, arı alerjisinin dolaylı bir ölçüsü olan duyarlılaşma oranlarının, Mersin yöresindeki durumunu belirlemek amacıyla yaptık. Gereç ve Yöntem: Yaş ortalamaları 38,4 yıl olan 86 erkek ve 123 kadın olmak üzere 209 gönüllüde, sorgulama, nefelometrik yöntemle total IgE, fluoroimmünoassay yöntemi ile fadiotop ölçümleri ile beraber, apidae, vespidae ve polistes venomlarına karşı epidermal/intradermal test uygulayarak duyarlılaşma oranlarını araştırdık. Bulgular: İki yüz dokuz olguda her üç venom türüne karşı duyarlılaşma oranını %21 bulduk. Venom duyarlılığı olan kişiler arasında birden çok venoma karşı duyarlı olanların oranı %52,3 idi. Sorgulama sonucunda, arı sokması ile oluşan reaksiyonların, %80’inin normal reaksiyon, %11’inin geniş lokal reaksiyon, %9’unun sistemik reaksiyon olduğu bulundu. Geniş lokal reaksiyon tarif eden olguların %23,5’unda, sistemik reaksiyon tarif eden olguların %21,5’inde deri testi pozitif idi. Erkeklerle kadınlar arasında; stratifiye edilen yaş grupları arasında; total IgE pozitif ve negatif olanlar arasında; Phadiotop pozitifliği olanlar ve olmayanlar arasında; kırsal ve kentsel bölgede oturanlar arasında; arı sokma sayısı bakımından; son arı sokmasından itibaren geçen zaman açısından ve reaksiyon türleri bakımından duyarlılaşma oranları arasında fark bulunmadı. Sonuç: Mersin yöresinde arı venomlarına karşı duyarlılık oranının oldukça yüksek olduğu, ama duyarlılaşma titrasyonunun düşük düzeyde olduğu; dolayısıyla arı venom alerjisinin önemli bir sağlık sorunu olabileceği görülmektedir.

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Cite This Article

ŞENEL, E., GEZER, D. (2022). The sensitization rates of Hymenoptera venom in Mersin region. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 46 - Sayı: 4, 196–201. https://ajindex.com/articles/621926

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