Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2013 / Cilt: 47 - Sayı: 2

Evaluationofcutaneous manifestations according to the time in renal transplant recipients

Renaltransplantasyon hastalarında gözlenen deri bulgularının süreye göre değişiminin değerlendirilmesi

Pages
88–93
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the results obtained from the patient groups, it was found that gender, length of post-transplant period, and use of immunosuppressant drugs do not influence the clinicamanifestations of patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: This study is conducted to determine the prevalence and clinical characteristics of cutaneous manifestations in renal transplant patients.
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Key Findings & Data:Materials and Methods: Hospital records of 116 renal transplant patients were retrospectively investigated.
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Conclusion & Impact:According to the results obtained from the patient groups, it was found that gender, length of post-transplant period, and use of immunosuppressant drugs do not influence the clinicamanifestations of patients.
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Design: This study is conducted to determine the prevalence and clinical characteristics of cutaneous manifestations in renal transplant patients. Materials and Methods: Hospital records of 116 renal transplant patients were retrospectively investigated. The data obtained from patients who had 6 months follow-up period were evaluated. There were 68 (58.6%) males and 48 (41.4%) females aged between 10 and 68 years (mean=36.6 years). Detailed dermatologic examination was performed. The patients were grouped according to gender (male-female), posttransplant period (1-5 years, 5-10 years, >10 years) and the drugs used (cyclosporin, tacrolimus, other than these two immunosuppressant drugs). Results: The most common cutaneous manifestations were infectious. The dermatological findings were onychomycosis (13), tinea pedis (9), acneiform disorders (15), and warts (9). The clinical evaluation after 6 months has also demonstrated the same result. Among the evaluated patients, 7% showed premalignant or malignant manifestations on clinical examination. According to the results obtained from the patient groups, it was found that gender, length of post-transplant period, and use of immunosuppressant drugs do not influence the clinicamanifestations of patients. Conclusion: Dermatologic examinations and long-term follow-up should be performed in renal transplant patients. (Turkderm 2013; 47: 88-93)

Özet

Amaç: Bu çalışmada renal transplant hastalarında görülen deri bulgularının sıklığı ve klinik özelliklerin belirlenmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmamızda renal transplantasyon yapılan 116 hastanın dosyaları retrospektif olarak incelendi. Altı aylık takip süreleri olan hastaların verileri değerlendirmeye alındı. Yaşları 10-68 arasında değişen (ortalama 36,62) 68 erkek (%58,6) ve 48 kadın (%41,4) hasta vardı. Hastaların detaylı dermatolojik muayeneleri yapıldı. Hastalar cinsiyet (erkek-kadın), transplantasyon süresi (1-5 yıl, 5-10 yıl ve 10 yıl üzeri), ve kullanılan ilaçlara (siklosporin, takrolimus, bu iki ilaç dışında immünosüpresan ilacı kullanan) göre gruplandırıldı. Bulgular: Transplant hastalarında en sık görülen deri bulguları infeksiyon hastalıklarıydı. Deri bulguları onikomikoz (13), tinea pedis (9), akneiform lezyon (15) ve verruka (9) şeklinde kaydedildi. Altı ay sonraki klinik değerlendirmede benzer sonuçlar elde edildi. Klinik muayenede hastalarda %7 premalin ve malin lezyon tespit edildi. Hasta gruplarına göre elde edilen sonuçlarda cinsiyet, transplantasyon süresi ve kullanılan ilaçların klinik bulguları etkilemediği belirlendi. Sonuç: Renal transplant hastalarında dermatolojik muayene ve takipler uzun süreli olmalıdır. (Türk­derm 2013; 47: 88-93)

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Cite This Article

SEYAHİ, N., ALAGÖZ, S., ENGİN, B., KUTLUBAAY, Z., FENJANCHİ, A. R., KOTE, E., USMONOVA, L., AYDEMİR, H. E., ÖZ, Ö. C. (2022). Evaluationofcutaneous manifestations according to the time in renal transplant recipients. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 47 - Sayı: 2, 88–93. https://ajindex.com/articles/621894

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