Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2013 / Cilt: 47 - Sayı: 3

The clinical characteristics and thefrequency of metastatic cutaneous tumors among primary skin tumors

Derinin metastatik tümörlerininprimer deri tümörleri arasındaki sıklığı ve klinik özellikleri

Pages
166–169
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is important to recognize these tumors, because they can adress primary internal tumors. (Turkderm 2013; 47: 166-9)

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: Our aim was to investigate the clinical characteristics and the rate of metastatic skin lesions among all skin and skin appendage tumors.
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Key Findings & Data:Materials and Methods: We scanned the records of the histopathological diagnoses of all the skin tumors from the archives between 2006 to 2012 and recorded the data including age, gender, the diagnosis of internal malignancy, type of the cutaneous lesion, the location and the period between the appearance of the primary malignancies and cutaneous metastases.
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Conclusion & Impact:It is important to recognize these tumors, because they can adress primary internal tumors. (Turkderm 2013; 47: 166-9)
🔬Design:Research Article
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Design: Our aim was to investigate the clinical characteristics and the rate of metastatic skin lesions among all skin and skin appendage tumors. Materials and Methods: We scanned the records of the histopathological diagnoses of all the skin tumors from the archives between 2006 to 2012 and recorded the data including age, gender, the diagnosis of internal malignancy, type of the cutaneous lesion, the location and the period between the appearance of the primary malignancies and cutaneous metastases. Results: We found that 20 (0.48%) of 4126 skin tumors were diagnosed as metastatic skin tumors. Ten patients were men and ten were women (median age: 51.3±18.34). When considered primary internal malignancies of these patients, 6 patients were diagnosed with gastrointestinal malignancy, 4 - with lung cancer, 4 - with breast cancer, 3 - with malignant melanoma, 1 - with Ewing s sarcoma, 1 - with acute myeloblastic leukemia and 1 patient was diagnosed with prostatic cancer. The clinical appearance of the tumors was as follows: nodule (14), eczematized plaque (2), papule (2), papulonodule (1), and 1 infiltrated plaque (1). The localizations of the metastatic skin lesions were as follows: 7 lesions on the anterior trunk, 5 - in the abdominal wall, 2 - on the back, 2 - on the thigh, 2 - on the scalp, 1 - on the anterior arm, and 1 lesion on the inguinal site. We found that 3 patients (15%) were diagnosed with metastatic skin tumors before the diagnosis of internal malignancies while 17 patients (85%) were found to have metastatic skin lesions 18.97±24.76 months (1.5 -109 months) after the diagnosis of internal malignancies. Conclusion: Cutaneous metastatic skin tumors are rarely seen skin lesions. We found that cutaneous metastatic skin tumors are mostly nodular and on trunk localization. It is important to recognize these tumors, because they can adress primary internal tumors. (Turkderm 2013; 47: 166-9)

Özet

Amacımız: Derinin metastatik tümörlerinin, deri ve deri eki tümörleri arasındaki sıklığını ve klinik özelliklerini tespit etmekti. Gereç ve Yöntem: 2006-2012 yılları arasında histopatolojik inceleme sonucunda deri ve deri eki tümörü tanısı alan tüm hastalar hastanemiz arşivlerinden taranarak tespit edildi. Bu deri tümörleri içerisinden deri metastazı tanısı alan hastaların yaş ve cinsiyeti, internal malignite tanısı, deri lezyonunun tipi, lokalizasyonu ve internal malignite ile ilişkili ortaya çıkış süresi kayıt edildi. Bulgular: Histopatolojik inceleme sonucunda 4126 deri ve deri eki tümörü tanısı konan biyopsi örneği içerisinden 20sinin (%0,48) derinin metastatik tümörü tanısı aldığı tespit edildi. Bu tanıyı alan olguların 10u erkek, 10u kadın ve yaş ortalamaları 51,3±18,34dü. Altı hastada gastrointestinal sistem, 4 hastada akciğer kanseri 4 hastada meme kanseri, 3 hastada malign melanom,1 hastada Ewing sarkomu 1 hastada akut miyeloblastik lösemi (AML) ve 1 hastada da prostat kanseri derideki metastazın kaynağı olarak tespit edildi. Metastatik deri lezyonlarının 14'ü nodül, 2si ekzematize plak, 2si papül, 1i papülonodül, 1i infiltre plak şeklindeydi. Metastatik tümörlerin lokalizasyonları incelendiğinde 7 olguda göğüs ön duvarı 5 olguda abdomen, 2 olguda sırt, 2 olguda uyluk 2 olguda saçlı deri, 1 olguda ön kol ve 1 olguda ise inguinal bölge yerleşim bölgesiydi. Sadece 3 olgunun (%15) internal malignite tanısı öncesinde deri metastazı tanısı aldığı, 17 olgunun (%75) ise internal malignite tanısından ortalama 18,97±24,76 ay (1,5 -109 ay) sonra deriye metastaz tanısı aldığı tespit edildi. Sonuç: Derinin metastatik tümörleri nadir rastlanan tümörlerdir. Bu çalışmada deri metastazlarının en sık nodüler lezyonlar şeklinde ve gövde tutulumları ile başvurduğu gözlenmiştir. Bu tümörlerin kaynak aldıkları internal maligniteyi göstermeleri açısından dermatologlar tarafından tanınmaları önem taşımaktadır. (Türk­derm 2013; 47: 166-9)

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Cite This Article

SAKIZ, D., ATIŞ, G., TÜKENMEZ, G. D., KIVANÇ, İ. A. (2022). The clinical characteristics and thefrequency of metastatic cutaneous tumors among primary skin tumors. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 47 - Sayı: 3, 166–169. https://ajindex.com/articles/621893

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