Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2013 / Cilt: 47 - Sayı: 3

Does isotretinoin cause inflammatory bowel disease?

İsotretinoininflamatuvar barsak hastalığına yol açıyor mu?

Pages
130–135
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review summarizes the recent literature data on the possible association between isotretinoin and inflammatory bowel disease. (Turkderm 2013; 47: 130-5)

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Isotretinoin is used for the treatment of severe forms of acne and those resistant to therapy with systemic antibiotics and topical treatment.
📊
Key Findings & Data:Although isotretinoin is very effective in the treatment of acne vulgaris, isotretinoin has been associated with various adverse effects.
💡
Conclusion & Impact:This review summarizes the recent literature data on the possible association between isotretinoin and inflammatory bowel disease. (Turkderm 2013; 47: 130-5)
🔬Design:Review & Systematic Survey
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Isotretinoin is used for the treatment of severe forms of acne and those resistant to therapy with systemic antibiotics and topical treatment. Although isotretinoin is very effective in the treatment of acne vulgaris, isotretinoin has been associated with various adverse effects. Since its approval and widespread use, there have been case reports and retrospective studies suggesting a possible association between isotretinoin and inflammatory bowel disease. This review summarizes the recent literature data on the possible association between isotretinoin and inflammatory bowel disease. (Turkderm 2013; 47: 130-5)

Özet

sotretinoin şiddetli akne ve sistemik antibiyotikler ile topikal tedavilere dirençli aknenin tedavisinde kullanılmaktadır. Akne tedavisinde çok etkili olmasına karşın isotretinoinin pek çok yan etkileri bulunmaktadır. İlacın akne tedavisinde onaylanması ve yaygın olarak kullanılmasını takiben isotretinoin ve inflamatuvar barsak hastalığı arasında olası bir ilişkiyi düşündüren olgu raporları ve retrospektif çalışmalar bildirilmiştir. Bu derlemede isotretinoin ve inflamatuvar barsak hastalığı arasındaki olası ilişki güncel literatür bilgileriyle sunulmaktadır. (Türk­derm 2013; 47: 130-5)

🔖

Cite This Article

ADIŞEN, E., GÜRER, M. A. (2022). Does isotretinoin cause inflammatory bowel disease?. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 47 - Sayı: 3, 130–135. https://ajindex.com/articles/621889

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. William HC, Dellavalle RP, Garner S: Acne vulgaris. Lancet 2012;379:361- 72. Katsambas A, Stefanaki C, Cunliffe WJ: Guidelines for treating acne. Clin Dermatol 2004;22:439-44. Rademaker M: Adverse effects of isotretinoin: A retrospective review of 1743 patients started on isotretinoin. Australas J Dermatol 2010;51:248- 53. Hanson N, Leachman S: Safety issues in isotretinoin therapy. Semin Cutan Med Surg 2001;20:166-83.
  2. Ellis CN, Krach KJ: Uses and complications of isotretinoin therapy. J Am Acad Dermatol 2001;45:150-7.
  3. Lowenstein EB, Lowenstein EJ: Isotretinoin systemic therapy and the shadow cast upon dermatology's downtrodden hero. Clin Dermatol 201;29:652-61.
  4. Brelsford M, Beute TC: Preventing and managing the side effects of isotretinoin. Semin Cutan Med Surg 2008;27:197-206. Chapman MS: Vitamin a: history, current uses, and controversies. Semin Cutan Med Surg 2012;31:11-6. McLane J: Analysis of common side effects of isotretinoin. J Am Acad Dermatol 2001;45:188-94. de Groot AC: Dermatological drugs, topical agents, and cosmetics. Side Effects of Drugs Annual 1998;21:158-69.
  5. Goodfield MJD, Cox NH, Browser A, et al: Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010. Br J Dermatol 2010;162:1172-9.
  6. Goldsmith LA, Bolognia JL, Callen JP, et al: Consensus conference on the safe and optimal use of isotretinoin: Summary and recommendations. J Am Acad Dermatol 2004;50:900-6. Brodin MB: Inflammatory bowel disease and isotretinoin. J Am Acad Dermatol 1986;14:843. Martin P, Manley PN, Depew WT, et al: Isotretinoin-associated proctosigmoiditis. Gastroenterology 1987;93:606-9.
  7. McGinn T, Bewira C: Isoretinoin (Accutane) associated pancolitis. Am J Gastroenterol 1997;92:1682. Reniers DE, Howard JM: Isotretinoin-induced inflammatory bowel disease in an adolescent. Ann Pharmacother 2001;35:1214-6.
  8. Passier JL, Srivastava N, van Puijenbroek EP: Isotretinoin-induced inflammatory bowel disease. Neth J Med 2006;64:52-4.
  9. Bankar RN, Dafe CO, Köhnke A, Babu PS: Ulcerative colitis probably associated with isotretinoin. Indian J Gastroenterol 2006;25:171-2.
  10. Ahmed R, Pezzone M: Isoretinoin-associated ulcerative colitis. Am J Gastroenterol 2006;101:394. Rolanda C, Macedo G: Isotretinoin and inflammatory bowel disease. Am J Gastroenterol 2007;102:1330. Spada C, Riccioni ME, Marchese M, Familiari P, Costamagna G: Isotretinoin-associated pan-enteritis. J Clin Gastroenterol 2008;42:923-5.
  11. Papageorgiou NP, Altman A, Shoenfeld Y: Inflammatory bowel