Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2014 / Cilt: 48 - Sayı: 1

Etiological evaluation ofour patients with chronic urticaria

Kronikürtikerli olgularımızınetyolojik değerlendirmesi

Pages
13–16
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This result is similar to that in previous studies done in Turkish children with CU. (Turkderm 2014; 48: 13-6)

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: The etiology of chronic urticaria (CU) in childhood remains incompletely understood because of limited data.
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Key Findings & Data:Materials and Methods: We retrospectively analyzed the medical records of 67 children who attended our clinic and were diagnosed with CU between January 2001 and July 2012.
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Conclusion & Impact:This result is similar to that in previous studies done in Turkish children with CU. (Turkderm 2014; 48: 13-6)
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Design: The etiology of chronic urticaria (CU) in childhood remains incompletely understood because of limited data. In this study, we aimed to examine possible etiologies of CU in children. Materials and Methods: We retrospectively analyzed the medical records of 67 children who attended our clinic and were diagnosed with CU between January 2001 and July 2012. We investigated the etiological factors contributing to chronic urticaria, such as autoimmune disorders, malignancies and infections. Data were presented as mean±standard deviation (SD) and percentage (%). The comparisons between two groups were conducted using the Mann-Whitney U test. A p value of less than 0.05 was considered statistically significant. Results: Sixty-seven children who met the criteria for CU were included in the study. Male/female ratio was 0.5 and the mean age at onset of symptoms was 10.2±4.6 (range: 1-17) years. In 7% of patients, ANA titers were over 1/100. None of the patients had clinical features of a rheumatic disease, 13.7% of the subjects were positive for thyroid autoantibody. All of them were diagnosed with thyroiditis and received L-thyroxine treatment. Autologous serum skin test was positive in 42.8% of the patients (n=28). Conclusion: In children, infections and foods did not appear to be important causative factors for CU. As in adults, the etiology of CU in children is mainly related to autoreactive processes. This result is similar to that in previous studies done in Turkish children with CU. (Turkderm 2014; 48: 13-6)

Özet

Amaç: Çocukluk çağında sınırlı veri nedeniyle kronik ürtiker (KÜ) etyolojisi tam olarak anlaşılamamıştır. Bu çalışmada kronik ürtiker tanılı çocuklarda muhtemel etyolojik nedenlerin değerlendirilmesini amaçladık. Gereç ve Yöntem: Ocak 2011 ile Temmuz 2012 tarihleri arasında KÜ tanısı ile kliniğimizde izlenen 18 yaş altı 67 hasta retrospektif olarak analiz edildi. Kronik ürtiker tanılı hastalarda otoimmun hastalıklar, maliniteler, infeksiyonlar gibi etyolojik faktörler araştırıldı. Veriler ortalama±standart sapma (SD) ve yüzde (%) olarak belirtildi. İki grup karşılaştırması Mann-Whitney U metodu kullanılarak yapıldı. P1/100 saptanmış olup bu hastaların hiçbirinde romatolojik hastalığa ait klinik özellik belirtilmediği öğrenildi. Hastaların %13,7sinde tiroid otoantikor pozitifliği olup, hepsine tiroidit tanısı konulduğu ve L-Tiroxin tedavisi başlandığı görüldü. Otolog serum deri testi hastaların %48,2 (n=28)sinde pozitif olarak saptandı. Sonuç: Çocuklarda infeksiyonlar ve besinler önemli birer KÜ nedeni gibi görünmemektedir. Erişkinlerde olduğu gibi çocuklarda da KÜ etyolojisinde otoreaktif süreçler önemli bir yer tutmaktadır. Bu sonuçlar daha önce KÜ tanılı Türk çocuklarda yapılan çalışmalar ile benzer özelliktedir. (Türk­derm 2014; 48: 13-6)

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Cite This Article

ÇAĞLAYAN, Ş. S., ARIKAN, Z. A., KARAMAN, Ö., UZUNER, N., FIRINCI, F., IŞIK, S., UYSAL, P. (2022). Etiological evaluation ofour patients with chronic urticaria. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 48 - Sayı: 1, 13–16. https://ajindex.com/articles/621830

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References (14)

  1. Kanwar AJ, Greaves MW: Approach to the patient with chronic urticaria. Hosp Pract ( Minneap) 1996;31:175-189. Boguniewicz M: Chronic urticaria in children. Allergy Asthma Proc 2005; 26(1):13-7. Kaplan AP: Clinical practice. chronic urticaria and angioedema. N Eng J Med 2002; 346: 175-9.
  2. Volonakis M, Katsarou-Katsari A, Stratigos J: Etiologic factors in childhood chronic urticaria. Ann Allergy 1992 jul;69:161-5.
  3. Ghosh S, Kanwar A, Kaur S: Urticaria in children. Pediatr Dermatol 1993;10: 107-10.
  4. Harris A, Twarog FJ, Geha RS: Chronic urticaria in childhood. natural course and etiology. Ann Allergy 1983; 51: 161–5. Confino- Cohen R, Chodick G, Shalev V, et al: Chronic urticaria and autoimmunity: associations found in large population study. J Allergy Clin Immunol 2012; 129:1307-13
  5. Kozel MM, Bossuyt PM, Mekkes JR, Bos JD: Laboratory tests and identified diagnoses in patients with physical and chronic urticaria and angioedema: A systematic rewiev. J Am Acad Dermatol 2003; 48:409-16.
  6. Dreskin SC, Andrews KY: The thyroid and urticaria. Curr Opin Allergy Clin Immunol 2005;5:408-12
  7. Powell RJ, Du Toit GL, Siddique N, et al: BSACI guidelines for management of chronic urticaria and angio-edema. Clin Exp Allergy 2007; 37:631-50
  8. Jacobson KW, Branch LB, Nelson HS: Laboratory tests in chronic urticaria. JAMA 1980;243:1644-6.
  9. Martini A, Ravelli A, Albani S, et al: Hypocomplementemic urticarial vasculitis syndrome with severe systemic manifestations. J Pediatr 1994; 124:742-4. Brockow K: Urticaria pigmentosa. Immunol Allergy Clin North Am 2004;24:287-316.
  10. Howard R, Frieden IJ: Papular urticaria in children. Pediatr Dermatol 1996;13:246-9. Muckle TJ: The Muckle –Wells syndrome. Br J Dermatol 1979;100:87-92.
  11. Kulthanan K, Jiamton S, Thumpimukvatana N, et al: Chronic idiopathic urticaria: prevalence and clinical course. J Dermatol 2007; 34: 294–301. Kurt E, Metintas S, Basyigit I et al: Prevalence and Risk Factors of Allergies in Turkey (PARFAIT): results of a multicentre cross-sectional study in adults. Eur Respir J 2009;33(4):724-33.
  12. Mustafayev R, Civelek E, Orhan F, et al: Similar prevalence, different spectrum: IgE-mediated food allergy among Turkish adolescents. Allergol Immunopathol (Madr) 2013; 41:387-96.
  13. Orhan F, Karakas T, Cakir M, et al: Prevalence of immunoglobulin E-mediated food allergy in 6-9-year-old urban schoolchildren in the eastern Black Sea region of Turkey. Clin Exp Allergy 2009;39 (7):1027-35.
  14. Jirapongsananuruk O, Pongpreuksa S, Sangacharoenkit P, et al: I