AI Summary & Key Takeaways
AI InsightThe patient received chemotherapy following a below-knee amputation
📌 3 Key Takeaways
Abstract
Leiomyosarcoma (LMS) commonly arises from smooth muscles of visceral organs, such as uterus, gastrointestinal system and has a poor prognosis due to its metastatic potential. LMS derived from smooth muscles of the skin, named superficial LMS, usually indolent and has a better prognosis. Especially, LMS derived from pilar muscles is usually restricted to the dermis and rarely metastasizes. However, LMS originating from smooth muscles of subcutis behaves more aggressively and metastasizes more commonly. Here, we report a patient with giant superficial LMS on the lower extremity which invaded the underlying tissues like bone, tendons and joint and metastasized to the lung. The patient received chemotherapy following a below-knee amputation
Özet
Leiomyosarkomlar (LMS), kutanöz ya da visseral düz kas kökenli malign lezyonlardır. Uterus, gastrointestinal sistem gibi visseral düz kaslardan köken alan derin leiomyosarkomlar daha kötü prognoza sahiptir. Buna karşılık, derinin düz kaslarından köken alan yüzeyel LMS daha iyi prognoz gösterir. Dermal kökenli LMS nadiren metastaz yaparken subkutan gelişim gösteren tipi daha agresif olup daha sık metastaz yapar. Bu sunumda alt ektremitede yüzeyel yerleşim gösteren, kemik ve eklem invazyonu yanı sıra akciğer metastazı da yapan, diz altı ampütasyonu sonrasında kemoterapi uygulanan, dev bir LMS olgusunu sunacağız