Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2016 / Cilt: 50 - Sayı: 2

Evaluation of hyperandrogenemia and metabolic risk profile in women with postadolescent acne

Pages
54–58
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, postadolescent acne resistant to treatment may be considered as an early marker in the early diagnosis of PCOS in women to prevent the development of type 2 diabetes mellitus, MS and hypercholesterolemia.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: Postadolescent acne is a disease with relapses frequently seen in women.
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Key Findings & Data:In our study, we aimed to investigate the clinical and biochemical characteristics of hyperandrogenism and the prevalence of metabolic disorders, such as metabolic syndrome (MS) and dyslipidemia in women with postadolescent acne.Materials and Methods: This study was conducted on 50 women who attended our department with the complaint of postadolescent acne between July 2014 and December 2014.
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Conclusion & Impact:As a result, postadolescent acne resistant to treatment may be considered as an early marker in the early diagnosis of PCOS in women to prevent the development of type 2 diabetes mellitus, MS and hypercholesterolemia.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Design: Postadolescent acne is a disease with relapses frequently seen in women. Treatment is difficult. In our study, we aimed to investigate the clinical and biochemical characteristics of hyperandrogenism and the prevalence of metabolic disorders, such as metabolic syndrome (MS) and dyslipidemia in women with postadolescent acne.Materials and Methods: This study was conducted on 50 women who attended our department with the complaint of postadolescent acne between July 2014 and December 2014. The presence of androgenetic alopecia (AGA), hirsutism, polycystic ovary syndrome (PCOS), MS, dyslipidemia, and obesity was evaluated.Results: Seborrhea was present in 56%, hirsutism in 40%, AGA in 26%, and PCOS in 24% of women with postadolescent acne. The prevalence of MS and dyslipidemia was 24% and 44%, respectively. The prevalence of MS was significantly higher in patients with AGA and hirsutism. There was no association of MS with menstrual irregularity and PCOS. There was no significant association of dyslipidemia with AGA, hirsutism, PCOS, and menstrual irregularity. Conclusion: Clinical symptoms of hyperandrogenism, such as hirsutism, AGA, and PCOS were more common in women with postadolescent acne but androgenic hormone profile abnormalities were minimal. As a result, postadolescent acne resistant to treatment may be considered as an early marker in the early diagnosis of PCOS in women to prevent the development of type 2 diabetes mellitus, MS and hypercholesterolemia.

Özet

Amaç: Postadölesan akne, relapslarla seyreden kadınlarda sık görülen bir hastalıktır. Tedavisi zordur. Çalışmamızda postadölesan akneli kadınlarda hiperandrojeneminin klinik ve biyokimyasal özelliklerini ve metabolik sendrom (MS), dislipidemi gibi metabolik bozuklukların prevalansını değerlendirmeyi amaçladık.Gereç ve Yöntem: Çalışma Temmuz 2014 ve Aralık 2014 tarihleri arasında polikliniğimize postadölesan akne şikayeti ile başvuran 50 kadın hasta ile gerçekleştirildi. Hastalarda androgenetik alopesi (AGA), hirsutizm, polikistik over sendromu (PKOS), MS, dislipidemi ve obezite varlığı değerlendirildi.Bulgular: Postadölesan akneli kadınlarda sebore %56, hirsutizm %40, AGA %26, PKOS ise %24 oranında saptandı. Hastalarda MS prevalansı %24, dislipidemi prevalansı ise %44 idi. AGA ve hirsutismuslu olgularda MS oranı olmayanlara göre anlamlı derecede daha yüksek bulundu (p=0,001, p=0,044). Menstrüel düzensizlik ve PKOS mevcudiyeti ile MS varlığı açısından anlamlı bir ilişki kurulamadı (p=0,707, p=0,448). AGA, hirsutizm, PKOS ve menstrüel düzensizlik varlığı ile de dislipidemi açısından anlamlı ilişki bulunmadı (p=0,612, p=0,684, p=0,416, p=0,612)Sonuç: Postadölesan akneli kadınlarda hiperandrojenemi klinik bulgularından hirsutizm, AGA, PKOS yüksek oranda görüldü ancak androjenik hormon profilinde minimal anormallik saptandı. Sonuç olarak postadölesan dirençli akne; kadınlarda PKOS erken tanısında tip 2 diabetes mellitus, hiperkolesterolemi ve MS gelişimini önlemek için erken bir belirteç olarak düşünülebilir.

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Cite This Article

ARICA, D. A., YAYLI, S., BAYKAL, L. S. (2022). Evaluation of hyperandrogenemia and metabolic risk profile in women with postadolescent acne. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 50 - Sayı: 2, 54–58. https://ajindex.com/articles/621739

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