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Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2019 / Cilt: 53 - Sayı: 3

Demographic findings of patients diagnosed with pernio and comparison of their vitamin B12, folate and ferritin levels with a control group

Pernio tanısı konulan hastaların demografik bulgularının incelenmesi ve B12 vitamin, folat ve ferritin düzeylerinin kontrol grubu ile karşılaştırılması

Ebru KARAGÜN
Sevim BAYSAK
Pages
88–92
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the patients with pernio, it is likely that low Vitamin B12 was involved in the pernioetiology via the mechanism of vasoconstriction/vasodilatation

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: Pernio is an inflammatory disease that occurs in the acral regions of the body after exposure to cold.
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Key Findings & Data:The studyaimed to investigate the demographic findings of patients diagnosed with pernio and to determine the role of vitamin B12, folate and ferritinvalues in the pathogenesis of pernio.Materials and Methods: This study was conducted in pernio patients diagnosed at the Ağrı State Hospital, Dermatology Outpatient Clinic(Ağrı, Turkey) between September 2015 and April 2016.
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Conclusion & Impact:In the patients with pernio, it is likely that low Vitamin B12 was involved in the pernioetiology via the mechanism of vasoconstriction/vasodilatation
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Design: Pernio is an inflammatory disease that occurs in the acral regions of the body after exposure to cold. The studyaimed to investigate the demographic findings of patients diagnosed with pernio and to determine the role of vitamin B12, folate and ferritinvalues in the pathogenesis of pernio.Materials and Methods: This study was conducted in pernio patients diagnosed at the Ağrı State Hospital, Dermatology Outpatient Clinic(Ağrı, Turkey) between September 2015 and April 2016. The healthy control group participants were of similar age and gender. Vitamin B12,folate and ferritin levels were compared between the groups.Results: The patient and control groups were similar in age and gender. Vitamin B12 and ferritin levels were significantly lower in the patientgroup (p0.05).Conclusion: According to the data obtained from our study, when the demographic findings of the pernio patients were compared with thosein the literature, the results were found to be similar. In the patients with pernio, it is likely that low Vitamin B12 was involved in the pernioetiology via the mechanism of vasoconstriction/vasodilatation

Özet

Amaç: Pernio, soğuğa maruz kalma sonrasında vücudun akral bölgelerinde oluşan enflamatuvar bir hastalıktır. Çalışmamızda pernio hastalarının demografik bulguları incelenerek B12 vitamin, folat, ferritin düzeylerinin pernio patogenezindeki yerini bulmayı amaçladık. Gereç ve Yöntem: Bu çalışma, Eylül 2015-Nisan 2016 tarihleri arasında Ağrı Devlet Hastanesi Dermatololoji Polikliniği'ne başvuran pernio tanısı alan hastalar ile benzer yaş ve cinsiyet özelliklerine sahip kontrol grubunda gerçekleştirildi. Grupların B12 vitamin, folat, ferritin düzeyleri karşılaştırıldı. Bulgular: Hasta ve kontrol grupları yaş ve cinsiyet açısından benzerdi. Hasta grubunda B12 vitamin ve ferritin düzeyi anlamlı olarak düşüktü (p0,05). Sonuç: Çalışmamızda elde ettiğimiz veriler ışığında pernio hastaların demografik bulguları literatürdeki çalışmalarla karşılaştırıldığında, benzer sonuçlar bulunmuştur. Çalışmamızda B12 vitamin düşüklüğünün homosistein mekanizması üzerinden vazospazma yol açmak suretiyle pernio patogenezinde rol alması muhtemel olabileceği düşünülmektedir.

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Cite This Article

KARAGÜN, E., BAYSAK, S. (2022). Demographic findings of patients diagnosed with pernio and comparison of their vitamin B12, folate and ferritin levels with a control group. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 53 - Sayı: 3, 88–92. https://ajindex.com/articles/621674

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